Microbiotic and Genetic Variation in a Ubiquitous African Rodent, Mastomys natalensis- [electronic resource]
Microbiotic and Genetic Variation in a Ubiquitous African Rodent, Mastomys natalensis- [electronic resource]
- 자료유형
- 학위논문파일 국외
- 최종처리일시
- 20240214095924
- ISBN
- 9798380604284
- DDC
- 574.5
- 서명/저자
- Microbiotic and Genetic Variation in a Ubiquitous African Rodent, Mastomys natalensis - [electronic resource]
- 발행사항
- [S.l.]: : University of Florida., 2022
- 발행사항
- Ann Arbor : : ProQuest Dissertations & Theses,, 2022
- 형태사항
- 1 online resource(163 p.)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-04, Section: B.
- 주기사항
- Advisor: Austin, James.
- 학위논문주기
- Thesis (Ph.D.)--University of Florida, 2022.
- 사용제한주기
- This item must not be sold to any third party vendors.
- 초록/해제
- 요약As a result of human population growth, there has been an increase in urbanization and monoculture resulting in drastic changes in environmental conditions. Generalist species thrive in human-dominated ecosystems, and they do this by adapting to a novel set of conditions unavailable in their natural habitats.To examine the genomic signal of adaptive variation, I performed a comparative genomic analysis between two African rodents, M. natalensis and M. coucha. I generated Single Nucleotide Polymorphism (SNPs) dataset from M. natalensis populations from urban areas, commercial sugarcane fields, and rural areas under subsistence agriculture to examine molecular evidence of local adaptation. Finally, I generated a metagenomic dataset to characterize the variation in the gut microbiome of M. natalensis from the three land-use types.I found 90% similarity between the genomes of M. natalensis and M. coucha with significant enrichment of genes associated with reproduction. These findings may explain the high fecundity and generalist behavior observed in the Mastomys species, especially in M. natalensis.In addition, I found that the microbiome communities of rodents captured in sugarcane fields were more even and had higher species diversity than rodents from urban or rural areas. Likewise, the microbiome community of rodents trapped in the wet-warm season was more diverse than those captured in the cold-dry season. These findings may reflect the omnivorous dietary behavior and affinity for human-food resources observed in this species. I observed a positive correlation between microbial diversity and body mass index. Individuals from sugarcane and wet-warm season had the largest body mass index.Based on the analyses of 19,357 SNP loci, I found evidence of limited genetic structure, reflecting high gene flow, and limited genetic drift. In addition, I found 49 SNP loci under selection, with the main driver of putatively adaptive divergence between urban habitats and the other two land-use types.Efforts to understand the adaptation of generalist species need to involve a holistic approach to studying ecology and evolution. This study has provided some essential genomic resources that can be utilized to augment our knowledge of Mastomys ecology and evolution and help improve Ecologically Based Rodent Management.
- 일반주제명
- Ecology.
- 일반주제명
- Genetics.
- 일반주제명
- Environmental science.
- 키워드
- Adaptation
- 키워드
- Agro-ecosytem
- 키워드
- Genomics
- 키워드
- Gut microbiota
- 키워드
- Mastomys
- 키워드
- Urbanization
- 기타저자
- University of Florida Wildlife Ecology and Conservation
- 기본자료저록
- Dissertations Abstracts International. 85-04B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.