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A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants- [electronic resource]
A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants - [electronic...
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A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants- [electronic resource]
자료유형  
 학위논문파일 국외
최종처리일시  
20240214100045
ISBN  
9798380313056
DDC  
580
저자명  
Wickell, David Allen.
서명/저자  
A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants - [electronic resource]
발행사항  
[S.l.]: : Cornell University., 2023
발행사항  
Ann Arbor : : ProQuest Dissertations & Theses,, 2023
형태사항  
1 online resource(367 p.)
주기사항  
Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
주기사항  
Advisor: Li, Fay-Wei.
학위논문주기  
Thesis (Ph.D.)--Cornell University, 2023.
사용제한주기  
This item must not be sold to any third party vendors.
초록/해제  
요약In the modern era of plant biology, high-quality reference genome assemblies represent a foundational first step to many studies. They allow chromosome level structural analysis, characterization of various types of repetitive sequence, and identification of cis regulatory elements. Additionally, they improve many other types of research including functional annotation of genes and gene family analysis. The proliferation of relatively cheap high throughput sequencing and powerful computational resources has resulted in a surge of such assemblies being produced across the tree of life. However, the majority of this effort has been restricted to a relatively narrow range of phylogenetic diversity, focusing on a handful of agriculturally important groups. This has resulted in a significant bias in our understanding of many fundamental concepts and processes such as plant genome structure and organization, regulation of gene expression, and whole genome duplication, to name a few. My doctoral research seeks to expand our understanding of plant biology using a combination of genomic and transcriptomic data from ferns and lycophytes. I have utilized high quality genome assemblies from multiple species of ferns and lycophytes to gain unprecedented insight into processes and downstream effects of whole genome duplication and subsequent diploidization in seed-free plants. In addition, I have studied the convergent evolution of aquatic CAM in the lycophyte genus Isoetes using a combination of genomic and transcriptomic data. Lastly, I conducted species and population level phylogenetic analysis of Isoetes appalachiana, a widespread allopolyploid, to investigate the establishment of polyploid lineages and quantify subsequent gene flow between them. My research is diverse, spanning multiple disciplines as well as multiple phylogenetic lineages and ultimately represents a valuable resource for future forays into comparative genomics and transcriptomics of vascular plants.
일반주제명  
Plant sciences.
일반주제명  
Bioinformatics.
일반주제명  
Genetics.
키워드  
Genomics
키워드  
Pteridophytes
키워드  
Vascular plants
키워드  
Plant biology
키워드  
Seed-free plants
기타저자  
Cornell University Plant Biology
기본자료저록  
Dissertations Abstracts International. 85-03B.
기본자료저록  
Dissertation Abstract International
전자적 위치 및 접속  
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