Characterizing Prefrontal Tertiary Sulcal Morphology in Cognition, Development, and Evolution- [electronic resource]
Characterizing Prefrontal Tertiary Sulcal Morphology in Cognition, Development, and Evolution- [electronic resource]
- 자료유형
- 학위논문파일 국외
- 최종처리일시
- 20240214100118
- ISBN
- 9798380382267
- DDC
- 150
- 서명/저자
- Characterizing Prefrontal Tertiary Sulcal Morphology in Cognition, Development, and Evolution - [electronic resource]
- 발행사항
- [S.l.]: : University of California, Berkeley., 2023
- 발행사항
- Ann Arbor : : ProQuest Dissertations & Theses,, 2023
- 형태사항
- 1 online resource(113 p.)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
- 주기사항
- Advisor: Weiner, Kevin S.
- 학위논문주기
- Thesis (Ph.D.)--University of California, Berkeley, 2023.
- 사용제한주기
- This item must not be sold to any third party vendors.
- 초록/해제
- 요약A major goal of cognitive neuroscience is to understand the link between anatomical brain structure and cognition. In the work that follows, I characterize patterns of cortical folding in the prefrontal cortex and its relation to reasoning skill. A central thread running through this work is that by exploring the relationship between variability in anatomy and cognition, we can establish a link among cortical structure, function, and behavior.In Chapter 1, I test a classic hypothesis and ask whether small, variable structures known as tertiary sulci have cognitive relevance. By combining precise neuroanatomical techniques with a modern data-driven analysis pipeline, I show that these structures can be reliably identified in individuals across childhood and adolescence and that the depth of a subset of tertiary sulci explains additional variance in reasoning not accounted for by age.In Chapter 2, I further examine variability in the presence and prominence of cognitively relevant tertiary sulci in prefrontal cortex. I show that the variability in the presence of these structures is associated with variability in behavior and that these sulcal components have discernable functional connectivity profiles that relate to reasoning skill.Finally, in Chapter 3, I take a modern comparative anatomy approach and show that while these structures exist in chimpanzees, they are notably smaller, shallower, and more variable.This work lays out a methodological approach to compare structure, function, and behavior across individuals, age groups, and species. I show that sulci, particularly tertiary sulci, can be reliably identified across individuals and that variability in the presence and morphology of these structures can be linked to variability in cognition. The goal of these studies is not to claim that a single sulcus predicts a specific cognitive process, but rather to demonstrate that sulci are useful landmarks that can provide valuable insights into the relationship among cortical structure, function, and cognition.
- 일반주제명
- Psychology.
- 일반주제명
- Neurosciences.
- 일반주제명
- Morphology.
- 키워드
- Anatomy approach
- 키워드
- Cognition
- 키워드
- Development
- 키워드
- Reasoning skill
- 기타저자
- University of California, Berkeley Psychology
- 기본자료저록
- Dissertations Abstracts International. 85-03B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.