Cognitive Changes After High Volume Lumbar Puncture Versus 72-Hour External Lumbar Drain in Idiopathic Normal Pressure Hydrocephalus- [electronic resource]
Cognitive Changes After High Volume Lumbar Puncture Versus 72-Hour External Lumbar Drain in Idiopathic Normal Pressure Hydrocephalus- [electronic resource]
- 자료유형
- 학위논문파일 국외
- 최종처리일시
- 20240214101921
- ISBN
- 9798380614061
- DDC
- 157
- 저자명
- Herzog, Musya.
- 서명/저자
- Cognitive Changes After High Volume Lumbar Puncture Versus 72-Hour External Lumbar Drain in Idiopathic Normal Pressure Hydrocephalus - [electronic resource]
- 발행사항
- [S.l.]: : Columbia University., 2023
- 발행사항
- Ann Arbor : : ProQuest Dissertations & Theses,, 2023
- 형태사항
- 1 online resource(98 p.)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-04, Section: B.
- 주기사항
- Advisor: Verdeli, Lena.
- 학위논문주기
- Thesis (Ph.D.)--Columbia University, 2023.
- 사용제한주기
- This item must not be sold to any third party vendors.
- 초록/해제
- 요약A neuropsychological examination is often used in tandem with other measures to confirm the diagnosis of idiopathic Normal Pressure Hydrocephalus (iNPH) and to assess improvement in cognitive functioning after a lumbar puncture test. Improvement in symptoms is thought to predict benefit from installation of a ventriculoperitoneal shunt that redirects CSF from the brain. Although the 72-hour external lumbar drain (ELD) has long been the gold-standard drainage procedure, hospitals are increasingly opting for the high-volume lumbar puncture, during which 50ml of CSF is released over an hour before the patient is tested for improvement in symptoms. The primary aims of this study were to evaluate the changes in cognitive performance produced by the two LP procedures and to compare the results produced by each procedure. In a review of medical records, 40 patients met criteria for inclusion. Cognitive functioning in the 72-hour ELD (n = 10) group was compared to changes in patients in the HVLP group, in terms of baseline level of functioning and post-drain changes. Statistical methods used to determine change included ANOVA and Reliable Change Indices. Dominant-hand Grooved Pegboard Test showed significant change after lumbar puncture, with higher mean change in the 72-hour ELD group. 72-hour ELD patients had a slightly higher rate of Reliable Change than HVLP patients. Cognitive changes were bi-directional in both groups. Results suggest that changes in cognitive functioning after lumbar puncture occur in a minority of patients, regardless of procedure type, and may have low predictive value for VPS benefit.
- 일반주제명
- Clinical psychology.
- 일반주제명
- Cognitive psychology.
- 일반주제명
- Neurosciences.
- 키워드
- Neuropsychology
- 키워드
- Lumbar puncture
- 기타저자
- Columbia University Psychology
- 기본자료저록
- Dissertations Abstracts International. 85-04B.
- 기본자료저록
- Dissertation Abstract International
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