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The Relationship Between the Ordering of a Respiratory Viral Panel and the Presence of Acute Respiratory Illness and Influenza-Like Illness Symptoms Reported in the Electronic Medical Record- [electronic resource]
The Relationship Between the Ordering of a Respiratory Viral Panel and the Presence of Acu...
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The Relationship Between the Ordering of a Respiratory Viral Panel and the Presence of Acute Respiratory Illness and Influenza-Like Illness Symptoms Reported in the Electronic Medical Record- [electronic resource]
자료유형  
 학위논문파일 국외
최종처리일시  
20240214100350
ISBN  
9798379650759
DDC  
616.2
저자명  
Saul, Sean G.
서명/저자  
The Relationship Between the Ordering of a Respiratory Viral Panel and the Presence of Acute Respiratory Illness and Influenza-Like Illness Symptoms Reported in the Electronic Medical Record - [electronic resource]
발행사항  
[S.l.]: : University of Pittsburgh., 2020
발행사항  
Ann Arbor : : ProQuest Dissertations & Theses,, 2020
형태사항  
1 online resource(56 p.)
주기사항  
Source: Dissertations Abstracts International, Volume: 84-12, Section: B.
주기사항  
Advisor: Yassin, Mohamed H.;Nowalk, Mary Patricia;Frank, Linda R.
학위논문주기  
Thesis (M.P.H.)--University of Pittsburgh, 2020.
사용제한주기  
This item must not be sold to any third party vendors.
초록/해제  
요약Background: Influenza causes a large burden of hospitalizations in the United States (U.S.) each year. Influenza can lead to viral or bacterial pneumonia, dehydration, ear infections, and sinus infections, while serious complications can include inflammation of the heart (myocarditis), brain (encephalitis) or muscle (myositis, rhabdomyolysis) tissues, and multi-organ failure (for example, respiratory and kidney failure). Efficient mechanisms to accurately and quickly identify Influenza are needed, especially with respect to those with more severe illness.Methods: Chart reviews were conducted on a random sample of 1,029 patients appearing on a clinical informatics algorithm (CIA) generated list from 12/1/15 to 5/11/16. This list was used for recruitment in the HAIVEN study which is a Centers for Disease Control and Prevention (CDC)-funded, multicenter, test-negative, case-control study to determine the Influenza vaccine effectiveness (VE) against hospitalization. The CIA queried medical record databases of patients who were 18 years of age and older admitted to University of Pittsburgh Medical Center (UPMC) St. Margaret's Hospital in the previous 3 days using specified terms and diagnosis codes located in admission notes, emergency department notes, chief complaint upon registration, or presence of a respiratory viral panel charge (RVP). Using chart review data, each patient was deemed eligible for the study using 2 CDC descriptive eligibility boxes that aim to identify Acute Respiratory Illness (ARI) and Influenza-like Illness (ILI) using specified symptom-based and diagnosis-based terms. A Kappa test determined agreement between having a term listed on these eligibility boxes and RVP status. Binary and multivariate logistic regression tests were used to characterize the clinical features of those missed by the clinical RVP approach but found by the CDC's screening criteria and to characterize the clinical features of those missed by the CDC's screening criteria but found by the clinical RVP approach.Results: Of the 1,029 patients reviewed, 290 patients met the eligibility criteria and received an RVP ordered by a physician and 201 met the eligibility criteria but did not have an RVP ordered by a physician. A Kappa test resulted in a weak agreement between the 2 descriptive eligibly boxes and RVPs (kappa=.43). Both RVP status and the CDC's criteria were statistically significantly associated with fever, chest x-ray, and CT-scan.Conclusion: The findings of this study suggest that physicians are ordering RVPs for ILI only moderately well and improvement through standardized ordering criteria may be needed. Using a CIA for recruitment for Influenza and other respiratory diseases studies was beneficial. The regression model further confirmed these findings. A hybrid case definition for inpatient Influenza may be needed.Public Health Statement: The likelihood of being diagnosed with ARI or ILI by RVP was significantly higher if a patient had fever, chest x-ray, or CT-scan indicated. The likelihood of meeting the CDC's criteria was significantly higher if a patient had fever, chest x-ray, or lymphocyte count indicated in the EMR.
일반주제명  
Influenza.
일반주제명  
Viruses.
일반주제명  
Disease prevention.
일반주제명  
Disease control.
일반주제명  
Medicine.
일반주제명  
Health care management.
기타저자  
University of Pittsburgh.
기본자료저록  
Dissertations Abstracts International. 84-12B.
기본자료저록  
Dissertation Abstract International
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