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Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development- [electronic resource]
Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocogni...
Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development- [electronic resource]

Detailed Information

자료유형  
 학위논문파일 국외
최종처리일시  
20240214101211
ISBN  
9798380389563
DDC  
136
저자명  
Vogel, Sarah C.
서명/저자  
Gut Feelings: Examining the Role of the Gut Microbiota in Early Life Stress and Neurocognitive Development - [electronic resource]
발행사항  
[S.l.]: : New York University., 2023
발행사항  
Ann Arbor : : ProQuest Dissertations & Theses,, 2023
형태사항  
1 online resource(137 p.)
주기사항  
Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
주기사항  
Advisor: Brito, Natalie.
학위논문주기  
Thesis (Ph.D.)--New York University, 2023.
사용제한주기  
This item must not be sold to any third party vendors.
초록/해제  
요약Decades of research have demonstrated that early life stress can influence the development of multiple biological and psychological systems. Recently, the system of bacteria living in the gastrointestinal tract, known as the gut microbiome, has received increasing attention and interest as a potential mechanism by which stress influences development. The aim of this dissertation is to investigate the role of the gut microbiome as a potential mechanism linking common experiences of early life stress with differences in cognitive and emotional development in infancy. Through three studies across two samples I examined how stress is associated with the composition and diversity of the gut microbiome (paper 1), how the gut microbiome is associated with neural and behavioral markers of recognition memory (paper 2), and how associations between the gut microbiome and infant emotion regulation differ as a function of caregiver stress (paper 3). These three papers together add to a growing body of literature demonstrating the gut microbiome as an important biological system shaping cognitive development and mental health. In paper 1, we examined associations between caregiver physiological stress and family material strain and the diversity and composition of the infant gut microbiota at 12 months of age. We found a significant, positive association between caregiver physiological stress and diversity of the gut microbiota. Paper 2 extended these findings in the same sample and examined associations between the gut microbiome and neural and behavioral measures of recognition memories at 15 months. We identified abundance of several genera associated with recognition memory, including an unknown genus from the Lachnospiraceae family that was negatively associated with both neural and behavioral measures. In paper 3, we examined associations between the gut microbiome and infant emotion regulation, and how these associations differed based on caregiver stress. We identified one species of bacteria, Streptococcus salivarius, whose abundance was negatively associated with infant emotion regulation. Altogether, this dissertation presents a step forward in our scientific understanding of the role of the gut microbiome in typical development during infancy and highlights how variations in common experiences of stress may relate to population-level trends in mental and physical health.
일반주제명  
Developmental psychology.
일반주제명  
Microbiology.
일반주제명  
Neurosciences.
일반주제명  
Clinical psychology.
키워드  
Gut feelings
키워드  
Gut microbiota
키워드  
Neurocognitive development
키워드  
Behavioral markers
키워드  
Recognition memory
기타저자  
New York University Applied Psychology
기본자료저록  
Dissertations Abstracts International. 85-03B.
기본자료저록  
Dissertation Abstract International
전자적 위치 및 접속  
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■020    ▼a9798380389563
■035    ▼a(MiAaPQ)AAI30525531
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a136
■1001  ▼aVogel,  Sarah  C.
■24510▼aGut  Feelings:  Examining  the  Role  of  the  Gut  Microbiota  in  Early  Life  Stress  and  Neurocognitive  Development▼h[electronic  resource]
■260    ▼a[S.l.]:▼bNew  York  University.  ▼c2023
■260  1▼aAnn  Arbor  :▼bProQuest  Dissertations  &  Theses,  ▼c2023
■300    ▼a1  online  resource(137  p.)
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-03,  Section:  B.
■500    ▼aAdvisor:  Brito,  Natalie.
■5021  ▼aThesis  (Ph.D.)--New  York  University,  2023.
■506    ▼aThis  item  must  not  be  sold  to  any  third  party  vendors.
■520    ▼aDecades  of  research  have  demonstrated  that  early  life  stress  can  influence  the  development  of  multiple  biological  and  psychological  systems.  Recently,  the  system  of  bacteria  living  in  the  gastrointestinal  tract,  known  as  the  gut  microbiome,  has  received  increasing  attention  and  interest  as  a  potential  mechanism  by  which  stress  influences  development.  The  aim  of  this  dissertation  is  to  investigate  the  role  of  the  gut  microbiome  as  a  potential  mechanism  linking  common  experiences  of  early  life  stress  with  differences  in  cognitive  and  emotional  development  in  infancy.  Through  three  studies  across  two  samples  I  examined  how  stress  is  associated  with  the  composition  and  diversity  of  the  gut  microbiome  (paper  1),  how  the  gut  microbiome  is  associated  with  neural  and  behavioral  markers  of  recognition  memory  (paper  2),  and  how  associations  between  the  gut  microbiome  and  infant  emotion  regulation  differ  as  a  function  of  caregiver  stress  (paper  3).  These  three  papers  together  add  to  a  growing  body  of  literature  demonstrating  the  gut  microbiome  as  an  important  biological  system  shaping  cognitive  development  and  mental  health.  In  paper  1,  we  examined  associations  between  caregiver  physiological  stress  and  family  material  strain  and  the  diversity  and  composition  of  the  infant  gut  microbiota  at  12  months  of  age.  We  found  a  significant,  positive  association  between  caregiver  physiological  stress  and  diversity  of  the  gut  microbiota.  Paper  2  extended  these  findings  in  the  same  sample  and  examined  associations  between  the  gut  microbiome  and  neural  and  behavioral  measures  of  recognition  memories  at  15  months.  We  identified  abundance  of  several  genera  associated  with  recognition  memory,  including  an  unknown  genus  from  the  Lachnospiraceae  family  that  was  negatively  associated  with  both  neural  and  behavioral  measures.  In  paper  3,  we  examined  associations  between  the  gut  microbiome  and  infant  emotion  regulation,  and  how  these  associations  differed  based  on  caregiver  stress.  We  identified  one  species  of  bacteria,  Streptococcus  salivarius,  whose  abundance  was  negatively  associated  with  infant  emotion  regulation.  Altogether,  this  dissertation  presents  a  step  forward  in  our  scientific  understanding  of  the  role  of  the  gut  microbiome  in  typical  development  during  infancy  and  highlights  how  variations  in  common  experiences  of  stress  may  relate  to  population-level  trends  in  mental  and  physical  health.
■590    ▼aSchool  code:  0146.
■650  4▼aDevelopmental  psychology.
■650  4▼aMicrobiology.
■650  4▼aNeurosciences.
■650  4▼aClinical  psychology.
■653    ▼aGut  feelings
■653    ▼aGut  microbiota
■653    ▼aNeurocognitive  development
■653    ▼aBehavioral  markers
■653    ▼aRecognition  memory
■690    ▼a0620
■690    ▼a0410
■690    ▼a0317
■690    ▼a0622
■71020▼aNew  York  University▼bApplied  Psychology.
■7730  ▼tDissertations  Abstracts  International▼g85-03B.
■773    ▼tDissertation  Abstract  International
■790    ▼a0146
■791    ▼aPh.D.
■792    ▼a2023
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16933162▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.
■980    ▼a202402▼f2024

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