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Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity- [electronic resource]
Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity- [electronic resource]
상세정보
- 자료유형
- 학위논문파일 국외
- 최종처리일시
- 20240214095923
- ISBN
- 9798380605922
- DDC
- 636
- 저자명
- Wells, Teri L.
- 서명/저자
- Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity - [electronic resource]
- 발행사항
- [S.l.]: : University of Florida., 2022
- 발행사항
- Ann Arbor : : ProQuest Dissertations & Theses,, 2022
- 형태사항
- 1 online resource(130 p.)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-04, Section: B.
- 주기사항
- Advisor: Nelson, Corwin D.
- 학위논문주기
- Thesis (Ph.D.)--University of Florida, 2022.
- 사용제한주기
- This item must not be sold to any third party vendors.
- 초록/해제
- 요약The overall objectives of this dissertation were to study how nutrients, specifically vitamin D, and social grouping contributes to the immune function, health, growth and development of dairy cattle. Chapter 1 reviews the literature on the mastitis and heifer development and roles of vitamin D and calf housing on dairy calf development and immunity. Chapters 2 and 3 pertain to the effects of intramammary vitamin D treatments. Chapter 2 reports the results of testing the effect of dose and source of intramammary vitamin D treatments on gene expression and serum calcium. The work from Chapter 2 shows that 500 ug intramammary calcidiol (25-hydroxyvitamin D3) influenced milk cell gene expression without affecting serum Ca; whereas 50 ug calcitriol (1,25-dihydroxyvitamin D3) influenced milk cell gene expression but also increased serum Ca.Chapter 3 reports the effectiveness of intramammary vitamin D as a treatment for mastitis in dairy cattle. Calcitriol treatment administered at the onset of mastitis symptoms decreased the percentages of CD11b+CD14-(neutrophils) and concentrations of 8-iso-15R isoprostane in milk of infected quarters compared with placebo. Calcitriol did not affect bacteria or somatic cell 13counts in milk. The intramammary calcitriol treatment was not able to remove the S. uberis infection. Chapters 4 and 5 focus on heifer calf growth and immunity. Chapter 4 presents the effects of dietary calcidiol (1.7 ug/kg BW) on growth, health, and performance of dairy heifers until 3 months of age. Supplementing dietary calcidiol increased average body weight by 4 kg at weaning compared to control heifers possibly due to increased milk intake. Calcidiol decreased the concentration of monocytes in blood. Chapter 5 reports the effect of dairy calf housing on calf performance and immune competence. Housing treatments had no effect on calf body weights or average daily gain at weaning. Granulocyte percentage was decreased in GH calves indicating lower presence of infection. The concentration of CD T cells in blood was influenced by the interaction of social housing by age. Cell-mediated ex vivo recall responses to C. Albicans were influenced by social housing. Likewise, antibody-mediated responses to Keyhole limpet hemocyanin were influenced by the interaction of social hosing and age. Altogether, vitamin D nutrition and social housing are factors in immune development of dairy calves.
- 일반주제명
- Animal sciences.
- 일반주제명
- Genetics.
- 일반주제명
- Immunology.
- 일반주제명
- Nutrition.
- 키워드
- Animal welfare
- 키워드
- Dairy cattle
- 키워드
- Social housing
- 기타저자
- University of Florida Animal Sciences
- 기본자료저록
- Dissertations Abstracts International. 85-04B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
008240612s2022 us |||||||||||||||c||eng d■001000016931130
■00520240214095923
■006m o d
■007cr#unu||||||||
■020 ▼a9798380605922
■035 ▼a(MiAaPQ)AAI29319492
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a636
■1001 ▼aWells, Teri L.
■24510▼aManipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity▼h[electronic resource]
■260 ▼a[S.l.]:▼bUniversity of Florida. ▼c2022
■260 1▼aAnn Arbor :▼bProQuest Dissertations & Theses, ▼c2022
■300 ▼a1 online resource(130 p.)
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-04, Section: B.
■500 ▼aAdvisor: Nelson, Corwin D.
■5021 ▼aThesis (Ph.D.)--University of Florida, 2022.
■506 ▼aThis item must not be sold to any third party vendors.
■520 ▼aThe overall objectives of this dissertation were to study how nutrients, specifically vitamin D, and social grouping contributes to the immune function, health, growth and development of dairy cattle. Chapter 1 reviews the literature on the mastitis and heifer development and roles of vitamin D and calf housing on dairy calf development and immunity. Chapters 2 and 3 pertain to the effects of intramammary vitamin D treatments. Chapter 2 reports the results of testing the effect of dose and source of intramammary vitamin D treatments on gene expression and serum calcium. The work from Chapter 2 shows that 500 ug intramammary calcidiol (25-hydroxyvitamin D3) influenced milk cell gene expression without affecting serum Ca; whereas 50 ug calcitriol (1,25-dihydroxyvitamin D3) influenced milk cell gene expression but also increased serum Ca.Chapter 3 reports the effectiveness of intramammary vitamin D as a treatment for mastitis in dairy cattle. Calcitriol treatment administered at the onset of mastitis symptoms decreased the percentages of CD11b+CD14-(neutrophils) and concentrations of 8-iso-15R isoprostane in milk of infected quarters compared with placebo. Calcitriol did not affect bacteria or somatic cell 13counts in milk. The intramammary calcitriol treatment was not able to remove the S. uberis infection. Chapters 4 and 5 focus on heifer calf growth and immunity. Chapter 4 presents the effects of dietary calcidiol (1.7 ug/kg BW) on growth, health, and performance of dairy heifers until 3 months of age. Supplementing dietary calcidiol increased average body weight by 4 kg at weaning compared to control heifers possibly due to increased milk intake. Calcidiol decreased the concentration of monocytes in blood. Chapter 5 reports the effect of dairy calf housing on calf performance and immune competence. Housing treatments had no effect on calf body weights or average daily gain at weaning. Granulocyte percentage was decreased in GH calves indicating lower presence of infection. The concentration of CD T cells in blood was influenced by the interaction of social housing by age. Cell-mediated ex vivo recall responses to C. Albicans were influenced by social housing. Likewise, antibody-mediated responses to Keyhole limpet hemocyanin were influenced by the interaction of social hosing and age. Altogether, vitamin D nutrition and social housing are factors in immune development of dairy calves.
■590 ▼aSchool code: 0070.
■650 4▼aAnimal sciences.
■650 4▼aGenetics.
■650 4▼aImmunology.
■650 4▼aNutrition.
■653 ▼aAnimal welfare
■653 ▼aDairy cattle
■653 ▼aMammary gland immunity
■653 ▼aSocial housing
■653 ▼aVitamin D treatments
■690 ▼a0475
■690 ▼a0982
■690 ▼a0369
■690 ▼a0570
■71020▼aUniversity of Florida▼bAnimal Sciences.
■7730 ▼tDissertations Abstracts International▼g85-04B.
■773 ▼tDissertation Abstract International
■790 ▼a0070
■791 ▼aPh.D.
■792 ▼a2022
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16931130▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
■980 ▼a202402▼f2024
