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Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity- [electronic resource]
Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on H...
Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity- [electronic resource]

Detailed Information

자료유형  
 학위논문파일 국외
최종처리일시  
20240214095923
ISBN  
9798380605922
DDC  
636
저자명  
Wells, Teri L.
서명/저자  
Manipulation of Mammary Immunity in Dairy Cattle and Nutrition and Management Effects on Heifer Development and Immunity - [electronic resource]
발행사항  
[S.l.]: : University of Florida., 2022
발행사항  
Ann Arbor : : ProQuest Dissertations & Theses,, 2022
형태사항  
1 online resource(130 p.)
주기사항  
Source: Dissertations Abstracts International, Volume: 85-04, Section: B.
주기사항  
Advisor: Nelson, Corwin D.
학위논문주기  
Thesis (Ph.D.)--University of Florida, 2022.
사용제한주기  
This item must not be sold to any third party vendors.
초록/해제  
요약The overall objectives of this dissertation were to study how nutrients, specifically vitamin D, and social grouping contributes to the immune function, health, growth and development of dairy cattle. Chapter 1 reviews the literature on the mastitis and heifer development and roles of vitamin D and calf housing on dairy calf development and immunity. Chapters 2 and 3 pertain to the effects of intramammary vitamin D treatments. Chapter 2 reports the results of testing the effect of dose and source of intramammary vitamin D treatments on gene expression and serum calcium. The work from Chapter 2 shows that 500 ug intramammary calcidiol (25-hydroxyvitamin D3) influenced milk cell gene expression without affecting serum Ca; whereas 50 ug calcitriol (1,25-dihydroxyvitamin D3) influenced milk cell gene expression but also increased serum Ca.Chapter 3 reports the effectiveness of intramammary vitamin D as a treatment for mastitis in dairy cattle. Calcitriol treatment administered at the onset of mastitis symptoms decreased the percentages of CD11b+CD14-(neutrophils) and concentrations of 8-iso-15R isoprostane in milk of infected quarters compared with placebo. Calcitriol did not affect bacteria or somatic cell 13counts in milk. The intramammary calcitriol treatment was not able to remove the S. uberis infection. Chapters 4 and 5 focus on heifer calf growth and immunity. Chapter 4 presents the effects of dietary calcidiol (1.7 ug/kg BW) on growth, health, and performance of dairy heifers until 3 months of age. Supplementing dietary calcidiol increased average body weight by 4 kg at weaning compared to control heifers possibly due to increased milk intake. Calcidiol decreased the concentration of monocytes in blood. Chapter 5 reports the effect of dairy calf housing on calf performance and immune competence. Housing treatments had no effect on calf body weights or average daily gain at weaning. Granulocyte percentage was decreased in GH calves indicating lower presence of infection. The concentration of CD T cells in blood was influenced by the interaction of social housing by age. Cell-mediated ex vivo recall responses to C. Albicans were influenced by social housing. Likewise, antibody-mediated responses to Keyhole limpet hemocyanin were influenced by the interaction of social hosing and age. Altogether, vitamin D nutrition and social housing are factors in immune development of dairy calves.
일반주제명  
Animal sciences.
일반주제명  
Genetics.
일반주제명  
Immunology.
일반주제명  
Nutrition.
키워드  
Animal welfare
키워드  
Dairy cattle
키워드  
Mammary gland immunity
키워드  
Social housing
키워드  
Vitamin D treatments
기타저자  
University of Florida Animal Sciences
기본자료저록  
Dissertations Abstracts International. 85-04B.
기본자료저록  
Dissertation Abstract International
전자적 위치 및 접속  
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MARC

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■035    ▼a(MiAaPQ)AAI29319492
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a636
■1001  ▼aWells,  Teri  L.
■24510▼aManipulation  of  Mammary  Immunity  in  Dairy  Cattle  and  Nutrition  and  Management  Effects  on  Heifer  Development  and  Immunity▼h[electronic  resource]
■260    ▼a[S.l.]:▼bUniversity  of  Florida.  ▼c2022
■260  1▼aAnn  Arbor  :▼bProQuest  Dissertations  &  Theses,  ▼c2022
■300    ▼a1  online  resource(130  p.)
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-04,  Section:  B.
■500    ▼aAdvisor:  Nelson,  Corwin  D.
■5021  ▼aThesis  (Ph.D.)--University  of  Florida,  2022.
■506    ▼aThis  item  must  not  be  sold  to  any  third  party  vendors.
■520    ▼aThe  overall  objectives  of  this  dissertation  were  to  study  how  nutrients,  specifically  vitamin  D,  and  social  grouping  contributes  to  the  immune  function,  health,  growth  and  development  of  dairy  cattle.  Chapter  1  reviews  the  literature  on  the  mastitis  and  heifer  development  and  roles  of  vitamin  D  and  calf  housing  on  dairy  calf  development  and  immunity.  Chapters  2  and  3  pertain  to  the  effects  of  intramammary  vitamin  D  treatments.  Chapter  2  reports  the  results  of  testing  the  effect  of  dose  and  source  of  intramammary  vitamin  D  treatments  on  gene  expression  and  serum  calcium.  The  work  from  Chapter  2  shows  that  500  ug  intramammary  calcidiol  (25-hydroxyvitamin  D3)  influenced  milk  cell  gene  expression  without  affecting  serum  Ca;  whereas  50  ug  calcitriol  (1,25-dihydroxyvitamin  D3)  influenced  milk  cell  gene  expression  but  also  increased  serum  Ca.Chapter  3  reports  the  effectiveness  of  intramammary  vitamin  D  as  a  treatment  for  mastitis  in  dairy  cattle.  Calcitriol  treatment  administered  at  the  onset  of  mastitis  symptoms  decreased  the  percentages  of  CD11b+CD14-(neutrophils)  and  concentrations  of  8-iso-15R  isoprostane  in  milk  of  infected  quarters  compared  with  placebo.  Calcitriol  did  not  affect  bacteria  or  somatic  cell  13counts  in  milk.  The  intramammary  calcitriol  treatment  was  not  able  to  remove  the  S.  uberis  infection.  Chapters  4  and  5  focus  on  heifer  calf  growth  and  immunity.  Chapter  4  presents  the  effects  of  dietary  calcidiol  (1.7  ug/kg  BW)  on  growth,  health,  and  performance  of  dairy  heifers  until  3  months  of  age.  Supplementing  dietary  calcidiol  increased  average  body  weight  by  4  kg  at  weaning  compared  to  control  heifers  possibly  due  to  increased  milk  intake.  Calcidiol  decreased  the  concentration  of  monocytes  in  blood.  Chapter  5  reports  the  effect  of  dairy  calf  housing  on  calf  performance  and  immune  competence.  Housing  treatments  had  no  effect  on  calf  body  weights  or  average  daily  gain  at  weaning.  Granulocyte  percentage  was  decreased  in  GH  calves  indicating  lower  presence  of  infection.  The  concentration  of  CD  T  cells  in  blood  was  influenced  by  the  interaction  of  social  housing  by  age.  Cell-mediated  ex  vivo  recall  responses  to  C.  Albicans  were  influenced  by  social  housing.  Likewise,  antibody-mediated  responses  to  Keyhole  limpet  hemocyanin  were  influenced  by  the  interaction  of  social  hosing  and  age.  Altogether,  vitamin  D  nutrition  and  social  housing  are  factors  in  immune  development  of  dairy  calves.
■590    ▼aSchool  code:  0070.
■650  4▼aAnimal  sciences.
■650  4▼aGenetics.
■650  4▼aImmunology.
■650  4▼aNutrition.
■653    ▼aAnimal  welfare
■653    ▼aDairy  cattle
■653    ▼aMammary  gland  immunity
■653    ▼aSocial  housing
■653    ▼aVitamin  D  treatments
■690    ▼a0475
■690    ▼a0982
■690    ▼a0369
■690    ▼a0570
■71020▼aUniversity  of  Florida▼bAnimal  Sciences.
■7730  ▼tDissertations  Abstracts  International▼g85-04B.
■773    ▼tDissertation  Abstract  International
■790    ▼a0070
■791    ▼aPh.D.
■792    ▼a2022
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16931130▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.
■980    ▼a202402▼f2024

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