Health-Related Quality of Life and Work in Postmenopausal Women With Breast Cancer During Aromatase Inhibitor Therapy- [electronic resource]
Health-Related Quality of Life and Work in Postmenopausal Women With Breast Cancer During Aromatase Inhibitor Therapy- [electronic resource]
상세정보
- 자료유형
- 학위논문파일 국외
- 최종처리일시
- 20240214095924
- ISBN
- 9798379963507
- DDC
- 610.73
- 저자명
- Melnyk, Halia L.
- 서명/저자
- Health-Related Quality of Life and Work in Postmenopausal Women With Breast Cancer During Aromatase Inhibitor Therapy - [electronic resource]
- 발행사항
- [S.l.]: : New York University., 2022
- 발행사항
- Ann Arbor : : ProQuest Dissertations & Theses,, 2022
- 형태사항
- 1 online resource(204 p.)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-02, Section: B.
- 주기사항
- Advisor: Dickson, Victoria Vaughan;Merriman, John D.
- 학위논문주기
- Thesis (Ph.D.)--New York University, 2022.
- 사용제한주기
- This item must not be sold to any third party vendors.
- 초록/해제
- 요약Postmenopausal women with breast cancer on aromatase inhibitor (AI) therapy are vulnerable to diminished health-related quality of life (HRQoL). The first two study aims examined the relationship between AI treatment and HRQoL over an 18-month course of therapy. The third aim explored work-related factors, including significant employment events and job characteristics, as predictors of HRQoL. Data from the "Long-Term Trajectory of Cognitive Function Related to Anastrozole Use in Women (R01CA107408)" study were used for this secondary analysis. The participant sample (n=351) consisted of two AI cohorts (chemotherapy followed by AI therapy and AI therapy only) and a control group. Study variable selection was guided by the domains of disease/treatment effects, individual/interpersonal factors, and work environment presented in the Cancer Survivorship and Work Model. A total of eight linear mixed-effects models were constructed to examine the study aims for four SF-36 HRQoL components: Role Physical and Role Emotional scales and the Physical and Mental Component Summary scores. Goodness of fit tests were significant across all of the final models however the set of significant predictors varied. Skill discretion and decision authority job characteristics were significantly associated with HRQoL in the Role Physical and Mental Component Summary models. The interaction between treatment group and time was significant in four of the eight component models. These findings suggest the need for comprehensive multidisciplinary cancer survivorship programs to address the multi-pronged nature of factors that affect different aspects of HRQoL differently in this population.
- 일반주제명
- Nursing.
- 일반주제명
- Aging.
- 일반주제명
- Womens studies.
- 일반주제명
- Oncology.
- 키워드
- Breast cancer
- 키워드
- Employment
- 키워드
- Quality of life
- 키워드
- Women's health
- 키워드
- Work
- 기타저자
- New York University College of Nursing
- 기본자료저록
- Dissertations Abstracts International. 85-02B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
008240612s2022 us |||||||||||||||c||eng d■001000016931132
■00520240214095924
■006m o d
■007cr#unu||||||||
■020 ▼a9798379963507
■035 ▼a(MiAaPQ)AAI29319837
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a610.73
■1001 ▼aMelnyk, Halia L.
■24510▼aHealth-Related Quality of Life and Work in Postmenopausal Women With Breast Cancer During Aromatase Inhibitor Therapy▼h[electronic resource]
■260 ▼a[S.l.]:▼bNew York University. ▼c2022
■260 1▼aAnn Arbor :▼bProQuest Dissertations & Theses, ▼c2022
■300 ▼a1 online resource(204 p.)
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-02, Section: B.
■500 ▼aAdvisor: Dickson, Victoria Vaughan;Merriman, John D.
■5021 ▼aThesis (Ph.D.)--New York University, 2022.
■506 ▼aThis item must not be sold to any third party vendors.
■520 ▼aPostmenopausal women with breast cancer on aromatase inhibitor (AI) therapy are vulnerable to diminished health-related quality of life (HRQoL). The first two study aims examined the relationship between AI treatment and HRQoL over an 18-month course of therapy. The third aim explored work-related factors, including significant employment events and job characteristics, as predictors of HRQoL. Data from the "Long-Term Trajectory of Cognitive Function Related to Anastrozole Use in Women (R01CA107408)" study were used for this secondary analysis. The participant sample (n=351) consisted of two AI cohorts (chemotherapy followed by AI therapy and AI therapy only) and a control group. Study variable selection was guided by the domains of disease/treatment effects, individual/interpersonal factors, and work environment presented in the Cancer Survivorship and Work Model. A total of eight linear mixed-effects models were constructed to examine the study aims for four SF-36 HRQoL components: Role Physical and Role Emotional scales and the Physical and Mental Component Summary scores. Goodness of fit tests were significant across all of the final models however the set of significant predictors varied. Skill discretion and decision authority job characteristics were significantly associated with HRQoL in the Role Physical and Mental Component Summary models. The interaction between treatment group and time was significant in four of the eight component models. These findings suggest the need for comprehensive multidisciplinary cancer survivorship programs to address the multi-pronged nature of factors that affect different aspects of HRQoL differently in this population.
■590 ▼aSchool code: 0146.
■650 4▼aNursing.
■650 4▼aAging.
■650 4▼aWomens studies.
■650 4▼aOncology.
■653 ▼aAromatase inhibitor
■653 ▼aBreast cancer
■653 ▼aEmployment
■653 ▼aQuality of life
■653 ▼aWomen's health
■653 ▼aWork
■690 ▼a0569
■690 ▼a0493
■690 ▼a0453
■690 ▼a0992
■71020▼aNew York University▼bCollege of Nursing.
■7730 ▼tDissertations Abstracts International▼g85-02B.
■773 ▼tDissertation Abstract International
■790 ▼a0146
■791 ▼aPh.D.
■792 ▼a2022
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16931132▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
■980 ▼a202402▼f2024
