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A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants- [electronic resource]
A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants- [electronic resource]
상세정보
- 자료유형
- 학위논문파일 국외
- 최종처리일시
- 20240214100045
- ISBN
- 9798380313056
- DDC
- 580
- 서명/저자
- A Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants - [electronic resource]
- 발행사항
- [S.l.]: : Cornell University., 2023
- 발행사항
- Ann Arbor : : ProQuest Dissertations & Theses,, 2023
- 형태사항
- 1 online resource(367 p.)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
- 주기사항
- Advisor: Li, Fay-Wei.
- 학위논문주기
- Thesis (Ph.D.)--Cornell University, 2023.
- 사용제한주기
- This item must not be sold to any third party vendors.
- 초록/해제
- 요약In the modern era of plant biology, high-quality reference genome assemblies represent a foundational first step to many studies. They allow chromosome level structural analysis, characterization of various types of repetitive sequence, and identification of cis regulatory elements. Additionally, they improve many other types of research including functional annotation of genes and gene family analysis. The proliferation of relatively cheap high throughput sequencing and powerful computational resources has resulted in a surge of such assemblies being produced across the tree of life. However, the majority of this effort has been restricted to a relatively narrow range of phylogenetic diversity, focusing on a handful of agriculturally important groups. This has resulted in a significant bias in our understanding of many fundamental concepts and processes such as plant genome structure and organization, regulation of gene expression, and whole genome duplication, to name a few. My doctoral research seeks to expand our understanding of plant biology using a combination of genomic and transcriptomic data from ferns and lycophytes. I have utilized high quality genome assemblies from multiple species of ferns and lycophytes to gain unprecedented insight into processes and downstream effects of whole genome duplication and subsequent diploidization in seed-free plants. In addition, I have studied the convergent evolution of aquatic CAM in the lycophyte genus Isoetes using a combination of genomic and transcriptomic data. Lastly, I conducted species and population level phylogenetic analysis of Isoetes appalachiana, a widespread allopolyploid, to investigate the establishment of polyploid lineages and quantify subsequent gene flow between them. My research is diverse, spanning multiple disciplines as well as multiple phylogenetic lineages and ultimately represents a valuable resource for future forays into comparative genomics and transcriptomics of vascular plants.
- 일반주제명
- Plant sciences.
- 일반주제명
- Bioinformatics.
- 일반주제명
- Genetics.
- 키워드
- Genomics
- 키워드
- Pteridophytes
- 키워드
- Vascular plants
- 키워드
- Plant biology
- 키워드
- Seed-free plants
- 기타저자
- Cornell University Plant Biology
- 기본자료저록
- Dissertations Abstracts International. 85-03B.
- 기본자료저록
- Dissertation Abstract International
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■00520240214100045
■006m o d
■007cr#unu||||||||
■020 ▼a9798380313056
■035 ▼a(MiAaPQ)AAI30314528
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a580
■1001 ▼aWickell, David Allen.▼0(orcid)0000-0002-1389-6681
■24512▼aA Fistful of Genomes: Adventures in Comparative Genomics of Seed-Free Plants▼h[electronic resource]
■260 ▼a[S.l.]:▼bCornell University. ▼c2023
■260 1▼aAnn Arbor :▼bProQuest Dissertations & Theses, ▼c2023
■300 ▼a1 online resource(367 p.)
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-03, Section: B.
■500 ▼aAdvisor: Li, Fay-Wei.
■5021 ▼aThesis (Ph.D.)--Cornell University, 2023.
■506 ▼aThis item must not be sold to any third party vendors.
■520 ▼aIn the modern era of plant biology, high-quality reference genome assemblies represent a foundational first step to many studies. They allow chromosome level structural analysis, characterization of various types of repetitive sequence, and identification of cis regulatory elements. Additionally, they improve many other types of research including functional annotation of genes and gene family analysis. The proliferation of relatively cheap high throughput sequencing and powerful computational resources has resulted in a surge of such assemblies being produced across the tree of life. However, the majority of this effort has been restricted to a relatively narrow range of phylogenetic diversity, focusing on a handful of agriculturally important groups. This has resulted in a significant bias in our understanding of many fundamental concepts and processes such as plant genome structure and organization, regulation of gene expression, and whole genome duplication, to name a few. My doctoral research seeks to expand our understanding of plant biology using a combination of genomic and transcriptomic data from ferns and lycophytes. I have utilized high quality genome assemblies from multiple species of ferns and lycophytes to gain unprecedented insight into processes and downstream effects of whole genome duplication and subsequent diploidization in seed-free plants. In addition, I have studied the convergent evolution of aquatic CAM in the lycophyte genus Isoetes using a combination of genomic and transcriptomic data. Lastly, I conducted species and population level phylogenetic analysis of Isoetes appalachiana, a widespread allopolyploid, to investigate the establishment of polyploid lineages and quantify subsequent gene flow between them. My research is diverse, spanning multiple disciplines as well as multiple phylogenetic lineages and ultimately represents a valuable resource for future forays into comparative genomics and transcriptomics of vascular plants.
■590 ▼aSchool code: 0058.
■650 4▼aPlant sciences.
■650 4▼aBioinformatics.
■650 4▼aGenetics.
■653 ▼aGenomics
■653 ▼aPteridophytes
■653 ▼aVascular plants
■653 ▼aPlant biology
■653 ▼aSeed-free plants
■690 ▼a0479
■690 ▼a0369
■690 ▼a0715
■71020▼aCornell University▼bPlant Biology.
■7730 ▼tDissertations Abstracts International▼g85-03B.
■773 ▼tDissertation Abstract International
■790 ▼a0058
■791 ▼aPh.D.
■792 ▼a2023
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16931567▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
■980 ▼a202402▼f2024
