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Prophylactic Ondansetron Administration to Attenuate Spinal Anesthesia-Induced Hypotension in Cesarean Section- [electronic resource]
Prophylactic Ondansetron Administration to Attenuate Spinal Anesthesia-Induced Hypotension...
Prophylactic Ondansetron Administration to Attenuate Spinal Anesthesia-Induced Hypotension in Cesarean Section- [electronic resource]

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자료유형  
 학위논문파일 국외
최종처리일시  
20240214100120
ISBN  
9798379615888
DDC  
610.73
저자명  
Tran, Lan Phuong Thuy.
서명/저자  
Prophylactic Ondansetron Administration to Attenuate Spinal Anesthesia-Induced Hypotension in Cesarean Section - [electronic resource]
발행사항  
[S.l.]: : The University of Arizona., 2023
발행사항  
Ann Arbor : : ProQuest Dissertations & Theses,, 2023
형태사항  
1 online resource(82 p.)
주기사항  
Source: Dissertations Abstracts International, Volume: 84-12, Section: B.
주기사항  
Includes supplementary digital materials.
주기사항  
Advisor: Herring, Christopher.
학위논문주기  
Thesis (D.N.P.)--The University of Arizona, 2023.
사용제한주기  
This item must not be sold to any third party vendors.
초록/해제  
요약Purpose: This quality improvement (QI) project aims to evaluate the impact of the education provided to anesthesia providers on the prophylactic use of ondansetron to attenuate spinal anesthesia-induced hypotension (SAIH) in cesarean section. Knowledge acquisition and the intent to change practice will be measured to determine the impact.Background: Spinal anesthesia is a preferred technique in managing obstetric patients having cesarean section because it allows practitioners to avoid the potential complications associated with general anesthesia. Despite several proposed therapies, SAIH remains a prevalent adverse effect that manifests shortly after spinal block. The hypotension generated by spinal anesthesia is a result of suppression of the sympathetic nervous system (sympathectomy) and activation of the Bezold-Jarisch Reflex (BJR). The BJR activation exacerbates hypotension and can lead to asystole and cardiovascular collapse. Studies have shown that 5-hydroxytryptamine subtype 3 (5- HT3) receptor antagonists can effectively reduce BJR activation. Ondansetron is a 5-HT3 receptor antagonist linked to a reduction in the frequency and severity of SAIH.Methods: A presentation of an educational session to improve anesthesia providers' knowledge to promote the timely use of prophylactic ondansetron as an adjunct therapy to attenuate SAIH incidence in cesarean section. The impact outcomes of this educational session will be the measurement of the percentage of anesthesia providers reporting an improved knowledge and favorable intention towards incorporating the usage of timely prophylactic ondansetron in cesarean section in their daily care.Results: As only 40% of participants provided timely prophylactic ondansetron, as an adjunct, five minutes before to spinal block to prevent SAIH in cesarean section, a pre-intervention survey revealed the necessity for an educational session on the matter. The percentage grew to 100% after the presentation. Participants' knowledge enhancement and retention of almost 100% of the presentation showed in the 30-day post-interventional survey are directly correlated with the participant's willingness to continue to administer prophylactic ondansetron in a timely manner to attenuate SAIH in cesarean section.Conclusions: Following the educational presentation, anesthesia providers improved their knowledge and intention to use timely ondansetron as an adjunct therapy for attenuating SAIH incidents in cesarean section.
일반주제명  
Nursing.
일반주제명  
Medicine.
일반주제명  
Surgery.
키워드  
Spinal anesthesia-induced hypotension
키워드  
Quality improvement
키워드  
Anesthesia
키워드  
Bezold-Jarisch Reflex
키워드  
Spinal block
키워드  
Prophylactic ondansetron
기타저자  
The University of Arizona Nursing
기본자료저록  
Dissertations Abstracts International. 84-12B.
기본자료저록  
Dissertation Abstract International
전자적 위치 및 접속  
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MARC

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■006m          o    d                
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■020    ▼a9798379615888
■035    ▼a(MiAaPQ)AAI30424018
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a610.73
■1001  ▼aTran,  Lan  Phuong  Thuy.
■24510▼aProphylactic  Ondansetron  Administration  to  Attenuate  Spinal  Anesthesia-Induced  Hypotension  in  Cesarean  Section▼h[electronic  resource]
■260    ▼a[S.l.]:▼bThe  University  of  Arizona.  ▼c2023
■260  1▼aAnn  Arbor  :▼bProQuest  Dissertations  &  Theses,  ▼c2023
■300    ▼a1  online  resource(82  p.)
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  84-12,  Section:  B.
■500    ▼aIncludes  supplementary  digital  materials.
■500    ▼aAdvisor:  Herring,  Christopher.
■5021  ▼aThesis  (D.N.P.)--The  University  of  Arizona,  2023.
■506    ▼aThis  item  must  not  be  sold  to  any  third  party  vendors.
■520    ▼aPurpose:  This  quality  improvement  (QI)  project  aims  to  evaluate  the  impact  of  the  education  provided  to  anesthesia  providers  on  the  prophylactic  use  of  ondansetron  to  attenuate  spinal  anesthesia-induced  hypotension  (SAIH)  in  cesarean  section.  Knowledge  acquisition  and  the  intent  to  change  practice  will  be  measured  to  determine  the  impact.Background:  Spinal  anesthesia  is  a  preferred  technique  in  managing  obstetric  patients  having  cesarean  section  because  it  allows  practitioners  to  avoid  the  potential  complications  associated  with  general  anesthesia.  Despite  several  proposed  therapies,  SAIH  remains  a  prevalent  adverse  effect  that  manifests  shortly  after  spinal  block.  The  hypotension  generated  by  spinal  anesthesia  is  a  result  of  suppression  of  the  sympathetic  nervous  system  (sympathectomy)  and  activation  of  the  Bezold-Jarisch  Reflex  (BJR).  The  BJR  activation  exacerbates  hypotension  and  can  lead  to  asystole  and  cardiovascular  collapse.  Studies  have  shown  that  5-hydroxytryptamine  subtype  3  (5-  HT3)  receptor  antagonists  can  effectively  reduce  BJR  activation.  Ondansetron  is  a  5-HT3  receptor  antagonist  linked  to  a  reduction  in  the  frequency  and  severity  of  SAIH.Methods:  A  presentation  of  an  educational  session  to  improve  anesthesia  providers'  knowledge  to  promote  the  timely  use  of  prophylactic  ondansetron  as  an  adjunct  therapy  to  attenuate  SAIH  incidence  in  cesarean  section.  The  impact  outcomes  of  this  educational  session  will  be  the  measurement  of  the  percentage  of  anesthesia  providers  reporting  an  improved  knowledge  and  favorable  intention  towards  incorporating  the  usage  of  timely  prophylactic  ondansetron  in  cesarean  section  in  their  daily  care.Results:  As  only  40%  of  participants  provided  timely  prophylactic  ondansetron,  as  an  adjunct,  five  minutes  before  to  spinal  block  to  prevent  SAIH  in  cesarean  section,  a  pre-intervention survey  revealed  the  necessity  for  an  educational  session  on  the  matter.  The  percentage  grew  to  100%  after  the  presentation.  Participants'  knowledge  enhancement  and  retention  of  almost  100%  of  the  presentation  showed  in  the  30-day  post-interventional  survey  are  directly  correlated  with  the  participant's  willingness  to  continue  to  administer  prophylactic  ondansetron  in  a  timely  manner  to  attenuate  SAIH  in  cesarean  section.Conclusions:  Following  the  educational  presentation,  anesthesia  providers  improved  their  knowledge  and  intention  to  use  timely  ondansetron  as  an  adjunct  therapy  for  attenuating  SAIH  incidents  in  cesarean  section.
■590    ▼aSchool  code:  0009.
■650  4▼aNursing.
■650  4▼aMedicine.
■650  4▼aSurgery.
■653    ▼aSpinal  anesthesia-induced  hypotension
■653    ▼aQuality  improvement
■653    ▼aAnesthesia
■653    ▼aBezold-Jarisch  Reflex
■653    ▼aSpinal  block
■653    ▼aProphylactic  ondansetron
■690    ▼a0569
■690    ▼a0576
■690    ▼a0564
■71020▼aThe  University  of  Arizona▼bNursing.
■7730  ▼tDissertations  Abstracts  International▼g84-12B.
■773    ▼tDissertation  Abstract  International
■790    ▼a0009
■791    ▼aD.N.P.
■792    ▼a2023
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16931805▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.
■980    ▼a202402▼f2024

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