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Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship- [electronic resource]
Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship - [electroni...
Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship- [electronic resource]

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자료유형  
 학위논문파일 국외
최종처리일시  
20240214101938
ISBN  
9798380198905
DDC  
610.73
저자명  
Hamidi, Maryam.
서명/저자  
Microbiome of Preterm Infant from Skin-to-Skin Care to Antibiotic Stewardship - [electronic resource]
발행사항  
[S.l.]: : Case Western Reserve University., 2021
발행사항  
Ann Arbor : : ProQuest Dissertations & Theses,, 2021
형태사항  
1 online resource(118 p.)
주기사항  
Source: Dissertations Abstracts International, Volume: 85-03, Section: B.
주기사항  
Advisor: Darrah, Rebecca; Levine, Alan.
학위논문주기  
Thesis (Ph.D.)--Case Western Reserve University, 2021.
사용제한주기  
This item must not be sold to any third party vendors.
초록/해제  
요약The primary intestinal microbial colonization in preterm infants (PIs) is influenced by gestational age (GA), delivery mode, and antibiotics exposure. There are few effective interventions designed to improve microbial colonization among PIs, and therefore this is a critical issue for nurses in the neonatal intensive care unit (NICU). This work introduces three independent studies that have direct or indirect impact on improving the gut microbial colonization among PIs. Study number one was a descriptive observational study to explore the impact of skin -to-skin care on intestinal microbial diversity and composition of PIs. The participants of the study were 25 mother-infant dyads (infants 'GA: 31-34 weeks). Mothers recorded the duration of skin-to-skin care in a diary and infants were subsequently divided in low and high groups of skin-to-skin care. The microbial DNA from mother's chest skin swab and infants' oral swabs and stool samples were analyzed using 16s rRNA gene sequencing. Our results showed differences in intestinal microbial composition and diversity between low and high groups of skin-to-skin care. That suggests that STS care may affect the microbial composition and diversity in the gut of preterm infants. Antibiotics are a major risk factor which disturbs gut microbial colonization. Antibiotics are the most prescribed medications in the NICUs. Antibiotic stewardship programs have reduced the unnecessary antibiotic therapy. The second study is a review of literature about the concept of antimicrobial stewardship. It also identifies the obstacles which prevent nursing teams from implementing the principles of antimicrobial stewardship in the NICUs. The third study is a descriptive survey study that identifies nurses' attitudes toward antibiotic stewardship programs in the NICUs. The survey questionnaire was posted on the National Association of Neonatal Network (NANN). The results of this study identified that although the majority of nurses were very familiar with the term "antibiotic stewardship", their responses to the questions related to the component of antibiotic stewardship program were inconsistent. In summary these studies are important to help identify solutions to enhance the primary seeding of microbial communities among the vulnerable population of preterm infants.
일반주제명  
Nursing.
일반주제명  
Microbiology.
일반주제명  
Obstetrics.
일반주제명  
Immunology.
키워드  
Preterm infant
키워드  
Antibiotic stewardship
키워드  
Microbiome
키워드  
Mother-infant dyads
키워드  
Skin-to-skin care
기타저자  
Case Western Reserve University Nursing
기본자료저록  
Dissertations Abstracts International. 85-03B.
기본자료저록  
Dissertation Abstract International
전자적 위치 및 접속  
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MARC

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■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a610.73
■1001  ▼aHamidi,  Maryam.
■24510▼aMicrobiome  of  Preterm  Infant  from  Skin-to-Skin  Care  to  Antibiotic  Stewardship▼h[electronic  resource]
■260    ▼a[S.l.]:▼bCase  Western  Reserve  University.  ▼c2021
■260  1▼aAnn  Arbor  :▼bProQuest  Dissertations  &  Theses,  ▼c2021
■300    ▼a1  online  resource(118  p.)
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-03,  Section:  B.
■500    ▼aAdvisor:  Darrah,  Rebecca;  Levine,  Alan.
■5021  ▼aThesis  (Ph.D.)--Case  Western  Reserve  University,  2021.
■506    ▼aThis  item  must  not  be  sold  to  any  third  party  vendors.
■520    ▼aThe  primary  intestinal  microbial  colonization  in  preterm  infants  (PIs)  is  influenced  by  gestational  age  (GA),  delivery  mode,  and  antibiotics  exposure.  There  are  few  effective  interventions  designed  to  improve  microbial  colonization  among  PIs,  and  therefore  this  is  a  critical  issue  for  nurses  in  the  neonatal  intensive  care  unit  (NICU).    This  work  introduces  three  independent  studies  that  have  direct  or  indirect  impact  on  improving  the  gut  microbial  colonization  among  PIs.    Study  number  one  was  a  descriptive  observational  study  to  explore  the  impact  of  skin  -to-skin    care  on  intestinal  microbial  diversity  and  composition  of  PIs.  The  participants  of  the  study  were  25  mother-infant  dyads  (infants  'GA:  31-34  weeks).  Mothers  recorded  the  duration  of  skin-to-skin  care  in  a  diary  and  infants  were  subsequently  divided  in  low  and  high  groups  of  skin-to-skin  care.  The  microbial  DNA  from  mother's  chest  skin  swab  and  infants'  oral  swabs  and  stool  samples  were  analyzed  using  16s  rRNA  gene  sequencing.  Our  results  showed  differences  in  intestinal  microbial  composition  and  diversity  between  low  and  high  groups  of  skin-to-skin  care.  That  suggests  that  STS  care  may  affect  the  microbial  composition  and  diversity  in  the  gut  of  preterm  infants.      Antibiotics  are  a  major  risk  factor  which  disturbs  gut  microbial  colonization.  Antibiotics  are  the  most  prescribed  medications  in  the  NICUs.  Antibiotic  stewardship  programs  have  reduced  the  unnecessary  antibiotic  therapy.  The  second  study  is  a  review  of  literature  about  the  concept  of  antimicrobial  stewardship.  It  also  identifies  the  obstacles  which  prevent  nursing  teams  from  implementing  the  principles  of  antimicrobial  stewardship  in  the  NICUs.  The  third  study  is  a  descriptive  survey  study  that  identifies  nurses'  attitudes  toward  antibiotic  stewardship  programs  in  the  NICUs.    The  survey  questionnaire  was  posted  on  the  National  Association  of  Neonatal  Network  (NANN).  The  results  of  this  study  identified  that  although  the  majority  of  nurses  were  very  familiar  with  the  term  "antibiotic  stewardship",  their  responses  to  the  questions  related  to  the  component  of  antibiotic  stewardship  program  were  inconsistent.      In  summary  these  studies  are  important  to  help  identify  solutions  to  enhance  the  primary  seeding  of  microbial  communities  among  the  vulnerable  population  of  preterm  infants.
■590    ▼aSchool  code:  0042.
■650  4▼aNursing.
■650  4▼aMicrobiology.
■650  4▼aObstetrics.
■650  4▼aImmunology.
■653    ▼aPreterm  infant
■653    ▼aAntibiotic  stewardship
■653    ▼aMicrobiome
■653    ▼aMother-infant  dyads
■653    ▼aSkin-to-skin  care
■690    ▼a0569
■690    ▼a0982
■690    ▼a0410
■690    ▼a0380
■71020▼aCase  Western  Reserve  University▼bNursing.
■7730  ▼tDissertations  Abstracts  International▼g85-03B.
■773    ▼tDissertation  Abstract  International
■790    ▼a0042
■791    ▼aPh.D.
■792    ▼a2021
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T16935485▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.
■980    ▼a202402▼f2024

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