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From Beats to Biomarkers: Unlocking the Power of Cardiac Diagnostic Tools with Artificial Intelligence
From Beats to Biomarkers: Unlocking the Power of Cardiac Diagnostic Tools with Artificial ...
From Beats to Biomarkers: Unlocking the Power of Cardiac Diagnostic Tools with Artificial Intelligence

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20250211152750
ISBN  
9798342108911
DDC  
616
저자명  
Hughes, John Weston.
서명/저자  
From Beats to Biomarkers: Unlocking the Power of Cardiac Diagnostic Tools with Artificial Intelligence
발행사항  
[Sl] : Stanford University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
152 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-04, Section: B.
주기사항  
Advisor: Guestrin, Carlos;Zou, James;Kundaje, Anshul.
학위논문주기  
Thesis (Ph.D.)--Stanford University, 2024.
초록/해제  
요약Heart disease is the number one cause of mortality in the US and globally even as preventative and interventional care have improved significantly in the past decades, in part because treatment isn't getting to the right people at the right time. Hospitals collect huge amounts of cardiovascular data, in the form of imaging, biosignals, text, and structured data. Could artificial intelligence (AI) help use this data to improve outcomes? This thesis builds on work applying AI to echocardiogram and electrocardiogram data with the goal of improving the set of tasks AI used for, how models are evaluated and interpreted, and our understanding of what diagnostic modalities are capable of. We start by describing a new computer vision tool for detecting abnormal laboratory values from the echocardiogram. Next, we present a novel AI risk score for cardiovascular mortality and disease from the ECG, which in combination with current standard-of-care cardiovascular risk scores can improve risk stratification for decisions like statin prescription. Third, we demonstrate via case study a new way of thinking about deep learning for electrocardiography by exploring a range of risk scores for left ventricular systolic dysfunction (LVSD) ranging from single measurements taken from the ECG to deep learning models with hundreds of thousands of parameters. Finally, we present a novel deep learning phenome-wide association study, analyzing the connection between the ECG and over 500 different diseases.
일반주제명  
Cardiovascular disease
일반주제명  
Biomarkers
일반주제명  
Electrocardiography
일반주제명  
Medicine
일반주제명  
Public health
기타저자  
Stanford University.
기본자료저록  
Dissertations Abstracts International. 86-04B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aHughes,  John  Weston.
■24510▼aFrom  Beats  to  Biomarkers:  Unlocking  the  Power  of  Cardiac  Diagnostic  Tools  with  Artificial  Intelligence
■260    ▼a[Sl]▼bStanford  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a152  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-04,  Section:  B.
■500    ▼aAdvisor:  Guestrin,  Carlos;Zou,  James;Kundaje,  Anshul.
■5021  ▼aThesis  (Ph.D.)--Stanford  University,  2024.
■520    ▼aHeart  disease  is  the  number  one  cause  of  mortality  in  the  US  and  globally  even  as  preventative  and  interventional  care  have  improved  significantly  in  the  past  decades,  in  part  because  treatment  isn't  getting  to  the  right  people  at  the  right  time.  Hospitals  collect  huge  amounts  of  cardiovascular  data,  in  the  form  of  imaging,  biosignals,  text,  and  structured  data.  Could  artificial  intelligence  (AI)  help  use  this  data  to  improve  outcomes?  This  thesis  builds  on  work  applying  AI  to  echocardiogram  and  electrocardiogram  data  with  the  goal  of  improving  the  set  of  tasks  AI  used  for,  how  models  are  evaluated  and  interpreted,  and  our  understanding  of  what  diagnostic  modalities  are  capable  of.  We  start  by  describing  a  new  computer  vision  tool  for  detecting  abnormal  laboratory  values  from  the  echocardiogram.  Next,  we  present  a  novel  AI  risk  score  for  cardiovascular  mortality  and  disease  from  the  ECG,  which  in  combination  with  current  standard-of-care  cardiovascular  risk  scores  can  improve  risk  stratification  for  decisions  like  statin  prescription.  Third,  we  demonstrate  via  case  study  a  new  way  of  thinking  about  deep  learning  for  electrocardiography  by  exploring  a  range  of  risk  scores  for  left  ventricular  systolic  dysfunction  (LVSD)  ranging  from  single  measurements  taken  from  the  ECG  to  deep  learning  models  with  hundreds  of  thousands  of  parameters.  Finally,  we  present  a  novel  deep  learning  phenome-wide  association  study,  analyzing  the  connection  between  the  ECG  and  over  500  different  diseases.
■590    ▼aSchool  code:  0212.
■650  4▼aCardiovascular  disease
■650  4▼aBiomarkers
■650  4▼aElectrocardiography
■650  4▼aMedicine
■650  4▼aPublic  health
■690    ▼a0800
■690    ▼a0564
■690    ▼a0573
■71020▼aStanford  University.
■7730  ▼tDissertations  Abstracts  International▼g86-04B.
■790    ▼a0212
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17163763▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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