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5-MeO-DMT as a Mental Health Tool: Exploring Possible Mechanisms of Action, the Reactivation Phenomenon, and Historical-Cultural Perspectives on Its Use
5-MeO-DMT as a Mental Health Tool: Exploring Possible Mechanisms of Action, the Reactivation Phenomenon, and Historical-Cultural Perspectives on Its Use
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20250211152800
- ISBN
- 9798383684801
- DDC
- 150
- 서명/저자
- 5-MeO-DMT as a Mental Health Tool: Exploring Possible Mechanisms of Action, the Reactivation Phenomenon, and Historical-Cultural Perspectives on Its Use
- 발행사항
- [Sl] : The University of Wisconsin - Madison, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 229 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 86-02, Section: B.
- 주기사항
- Advisor: Raison, Charles.
- 학위논문주기
- Thesis (Ph.D.)--The University of Wisconsin - Madison, 2024.
- 초록/해제
- 요약The short-acting psychedelic 5-MeO-DMT is gaining attention as a novel treatment for psychiatric disorders. Given the current interest in this substance, this dissertation investigated three different relevant aspects related to 5-MeO-DMT. Manuscript 1 examined potential psychological mechanisms underlying 5-MeO-DMT's therapeutic effects. A cross-sectional survey of participants (n = 90, Mean age = 38.8) assessed changes in the psychological constructs of cognitive fusion, nature relatedness, and prosocial behavioral intentions before and after 5-MeO-DMT use. Significant decreases in cognitive fusion and increases in nature relatedness and prosocial intentions were noted, particularly associated with challenging and insightful experiences.Manuscript 2 explored the prevalence, predictors, and emotional valence of a complex and poorly understood phenomenon known as "reactivations" following 5-MeO-DMT use (n = 90, Mean age = 38.8). Reactivations were found to be common and predominantly experienced as positive or neutral events. Predictors of reactivation experiences were the amount of time planned ahead for a 5-MeO-DMT dose, and decreases in cognitive fusion from before-to-after 5-MeO-DMT use. Psychological insight effects were associated with greater likelihood of reactivations being perceived positively, while challenging effects were associated with lower likelihood of positive/neutral emotional valence.Manuscript 3 provided a comprehensive historical and cultural analysis of 5-MeO-DMT use, tracing its origins to ancient South American Indigenous practices. It also examined the symbolic significance of a toad motif among Mesoamerican cultures, and discussed modern applications of toad-derived 5-MeO-DMT in North America and globally. This historical-cultural perspective provides crucial context for understanding the current therapeutic interest in 5-MeO-DMT and the ethical considerations surrounding its use and sourcing.Taken together, this dissertation's findings contribute to the scientific literature on 5- MeO-DMT's potential psychological mechanisms of action, and provide helpful data regarding the reactivation phenomenon. Additionally, it provides a comprehensive historical-cultural perspective on 5-MeO-DMT use from ancient practices to modern applications, offering insights into the evolving cultural and societal perceptions of this compound and its potential role as a mental health tool.
- 일반주제명
- Psychology
- 일반주제명
- Mental health
- 일반주제명
- Clinical psychology
- 키워드
- Cognitive fusion
- 키워드
- Ego dissolution
- 키워드
- Well-being
- 기타저자
- The University of Wisconsin - Madison Human Ecology
- 기본자료저록
- Dissertations Abstracts International. 86-02B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a150
■1001 ▼aOrtiz Bernal, Ana Maria.
■24510▼a5-MeO-DMT as a Mental Health Tool: Exploring Possible Mechanisms of Action, the Reactivation Phenomenon, and Historical-Cultural Perspectives on Its Use
■260 ▼a[Sl]▼bThe University of Wisconsin - Madison▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a229 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 86-02, Section: B.
■500 ▼aAdvisor: Raison, Charles.
■5021 ▼aThesis (Ph.D.)--The University of Wisconsin - Madison, 2024.
■520 ▼aThe short-acting psychedelic 5-MeO-DMT is gaining attention as a novel treatment for psychiatric disorders. Given the current interest in this substance, this dissertation investigated three different relevant aspects related to 5-MeO-DMT. Manuscript 1 examined potential psychological mechanisms underlying 5-MeO-DMT's therapeutic effects. A cross-sectional survey of participants (n = 90, Mean age = 38.8) assessed changes in the psychological constructs of cognitive fusion, nature relatedness, and prosocial behavioral intentions before and after 5-MeO-DMT use. Significant decreases in cognitive fusion and increases in nature relatedness and prosocial intentions were noted, particularly associated with challenging and insightful experiences.Manuscript 2 explored the prevalence, predictors, and emotional valence of a complex and poorly understood phenomenon known as "reactivations" following 5-MeO-DMT use (n = 90, Mean age = 38.8). Reactivations were found to be common and predominantly experienced as positive or neutral events. Predictors of reactivation experiences were the amount of time planned ahead for a 5-MeO-DMT dose, and decreases in cognitive fusion from before-to-after 5-MeO-DMT use. Psychological insight effects were associated with greater likelihood of reactivations being perceived positively, while challenging effects were associated with lower likelihood of positive/neutral emotional valence.Manuscript 3 provided a comprehensive historical and cultural analysis of 5-MeO-DMT use, tracing its origins to ancient South American Indigenous practices. It also examined the symbolic significance of a toad motif among Mesoamerican cultures, and discussed modern applications of toad-derived 5-MeO-DMT in North America and globally. This historical-cultural perspective provides crucial context for understanding the current therapeutic interest in 5-MeO-DMT and the ethical considerations surrounding its use and sourcing.Taken together, this dissertation's findings contribute to the scientific literature on 5- MeO-DMT's potential psychological mechanisms of action, and provide helpful data regarding the reactivation phenomenon. Additionally, it provides a comprehensive historical-cultural perspective on 5-MeO-DMT use from ancient practices to modern applications, offering insights into the evolving cultural and societal perceptions of this compound and its potential role as a mental health tool.
■590 ▼aSchool code: 0262.
■650 4▼aPsychology
■650 4▼aLatin American literature
■650 4▼aMental health
■650 4▼aClinical psychology
■653 ▼a5-Methoxy-N,N-dimethyltryptamine
■653 ▼aCognitive fusion
■653 ▼aEgo dissolution
■653 ▼aNature relatedness
■653 ▼aProsocial behaviors
■653 ▼aWell-being
■690 ▼a0621
■690 ▼a0312
■690 ▼a0622
■690 ▼a0347
■71020▼aThe University of Wisconsin - Madison▼bHuman Ecology.
■7730 ▼tDissertations Abstracts International▼g86-02B.
■790 ▼a0262
■791 ▼aPh.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17163841▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


