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Anhedonia as a Transdiagnostic Symptom: Implications for Cognition and White Matter Development
Anhedonia as a Transdiagnostic Symptom: Implications for Cognition and White Matter Development
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20250211152037
- ISBN
- 9798383202074
- DDC
- 150
- 서명/저자
- Anhedonia as a Transdiagnostic Symptom: Implications for Cognition and White Matter Development
- 발행사항
- [Sl] : University of California, Los Angeles, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 93 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 86-01, Section: B.
- 주기사항
- Advisor: Karlsgodt, Katherine H.
- 학위논문주기
- Thesis (Ph.D.)--University of California, Los Angeles, 2024.
- 초록/해제
- 요약Anhedonia is a transdiagnostic symptom characterized by the loss of the experience of pleasure from typically enjoyable activities. An established body of research has explored the impact of anhedonia on functioning and long-term outcomes in psychiatric populations, and emerging research has examined the role of anhedonia in adolescents with no psychiatric diagnosis. Anhedonia has been found to impact goal-directed behavior, reward processing, and future-oriented thinking. These behaviors are associated with cognitive abilities, which include both "hot" and "cold" cognition. These two cognitive systems develop throughout adolescence and are impacted in numerous psychiatric disorders. However, existing work has not provided a clear picture of how these pieces - anhedonia, adolescent development, and cognitive systems - fit together across diagnostic categories.The goal of this dissertation, which comprises three studies, was to bridge this gap by providing an in-depth look at anhedonia across adolescence and early adulthood using a dimensional lens and multiple modalities, including self-report, task performance, and brain imaging. In Study 1, I investigated associations between subcategories of anhedonia and aspects of risk-taking behavior in university students using hierarchical linear regression. Individuals who experienced less anticipatory pleasure (i.e., looking forward to an activity) engaged in more risk-taking behavior. In Study 2, I expanded these findings by investigating relationships among anhedonia, risk-taking behavior, risk perception, and working memory in adolescents across a wider age range using linear regression and a moderation analysis. I replicated the positive association between anhedonia and risk-taking behavior and found a positive relationship between age and working memory performance. The hypothesized moderation model was not significant. In Study 3, I examined the associations among psychosis diagnosis, anhedonia, and white matter integrity in adolescents using linear regression and a linear mixed model. I found a significant group difference in a frontrostriatal tract associated with "hot" cognition, and a significant negative relationship between anhedonia and integrity in a white matter bundle associated with "cold" cognition. I highlight the need to continue exploring relationships among anhedonia, cognition, and white matter in adolescence. The implications of this work, including further illumination of the impact of anhedonia on functioning across diagnoses, are also discussed.
- 일반주제명
- Psychology
- 일반주제명
- Mental health
- 일반주제명
- Cognitive psychology
- 일반주제명
- Clinical psychology
- 키워드
- Anhedonia
- 키워드
- Cognition
- 기타저자
- University of California, Los Angeles Psychology 0780
- 기본자료저록
- Dissertations Abstracts International. 86-01B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a150
■1001 ▼aCurrin, Danielle Leigh.
■24510▼aAnhedonia as a Transdiagnostic Symptom: Implications for Cognition and White Matter Development
■260 ▼a[Sl]▼bUniversity of California, Los Angeles▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a93 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 86-01, Section: B.
■500 ▼aAdvisor: Karlsgodt, Katherine H.
■5021 ▼aThesis (Ph.D.)--University of California, Los Angeles, 2024.
■520 ▼aAnhedonia is a transdiagnostic symptom characterized by the loss of the experience of pleasure from typically enjoyable activities. An established body of research has explored the impact of anhedonia on functioning and long-term outcomes in psychiatric populations, and emerging research has examined the role of anhedonia in adolescents with no psychiatric diagnosis. Anhedonia has been found to impact goal-directed behavior, reward processing, and future-oriented thinking. These behaviors are associated with cognitive abilities, which include both "hot" and "cold" cognition. These two cognitive systems develop throughout adolescence and are impacted in numerous psychiatric disorders. However, existing work has not provided a clear picture of how these pieces - anhedonia, adolescent development, and cognitive systems - fit together across diagnostic categories.The goal of this dissertation, which comprises three studies, was to bridge this gap by providing an in-depth look at anhedonia across adolescence and early adulthood using a dimensional lens and multiple modalities, including self-report, task performance, and brain imaging. In Study 1, I investigated associations between subcategories of anhedonia and aspects of risk-taking behavior in university students using hierarchical linear regression. Individuals who experienced less anticipatory pleasure (i.e., looking forward to an activity) engaged in more risk-taking behavior. In Study 2, I expanded these findings by investigating relationships among anhedonia, risk-taking behavior, risk perception, and working memory in adolescents across a wider age range using linear regression and a moderation analysis. I replicated the positive association between anhedonia and risk-taking behavior and found a positive relationship between age and working memory performance. The hypothesized moderation model was not significant. In Study 3, I examined the associations among psychosis diagnosis, anhedonia, and white matter integrity in adolescents using linear regression and a linear mixed model. I found a significant group difference in a frontrostriatal tract associated with "hot" cognition, and a significant negative relationship between anhedonia and integrity in a white matter bundle associated with "cold" cognition. I highlight the need to continue exploring relationships among anhedonia, cognition, and white matter in adolescence. The implications of this work, including further illumination of the impact of anhedonia on functioning across diagnoses, are also discussed.
■590 ▼aSchool code: 0031.
■650 4▼aPsychology
■650 4▼aMental health
■650 4▼aCognitive psychology
■650 4▼aClinical psychology
■653 ▼aAnhedonia
■653 ▼aTransdiagnostic symptom
■653 ▼aCognition
■653 ▼aWhite matter development
■653 ▼aPsychiatric disorders
■690 ▼a0621
■690 ▼a0347
■690 ▼a0622
■690 ▼a0633
■71020▼aUniversity of California, Los Angeles▼bPsychology 0780.
■7730 ▼tDissertations Abstracts International▼g86-01B.
■790 ▼a0031
■791 ▼aPh.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17162652▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
