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The Relationship Between Subjective Cognitive Decline and Objective Cognitive Performance Within Three Different Older Adult Samples
The Relationship Between Subjective Cognitive Decline and Objective Cognitive Performance ...
The Relationship Between Subjective Cognitive Decline and Objective Cognitive Performance Within Three Different Older Adult Samples

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자료유형  
 학위논문 서양
최종처리일시  
20250211150906
ISBN  
9798384102465
DDC  
157
저자명  
Nakhla, Marina Zaher.
서명/저자  
The Relationship Between Subjective Cognitive Decline and Objective Cognitive Performance Within Three Different Older Adult Samples
발행사항  
[Sl] : University of California, San Diego, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
141 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-03, Section: B.
주기사항  
Advisor: Zlatar, Zvinka Z.;Schiehser, Dawn M.
학위논문주기  
Thesis (Ph.D.)--University of California, San Diego, 2024.
초록/해제  
요약Older adults, including Non-Hispanic Whites (NHWs), Hispanics/Latinos, and those with neurodegenerative diseases (e.g., Parkinson's Disease: PD), are at risk for dementia. Subjective cognitive decline (SCD; perceived cognitive difficulties) may be an early risk marker of dementia. However, its neural correlates and utility to predict concurrent objective cognition across these different risk groups remain understudied. This 3-paper dissertation investigated associations of SCD with concurrent objective cognition across older adults at risk for dementia: 1) mostly NHWs (87% Caucasian) (age= 72.90), 2) Hispanics/Latinos (age= 73.97) versus NHWs (age= 71.81), and 3) PD (age= 67.56). Study 2 augmented Study 1 by examining ethnic differences in SCD reporting between NHWs and Hispanics/Latinos, while Study 3 expanded findings to neurodegenerative disease. Archival data was used from the UCSD WISE Lab, Shiley Marcos Alzheimer's Disease Research Center, and VA San Diego Healthcare System.Study 1 (Nakhla et al., 2024) investigated the relationship of self-reported SCD with objective cognition and cerebral blood flow (CBF) in a cognitively normal sample (N=52) with varying stroke risk status. Greater SCD severity was significantly associated with lower memory and entorhinal CBF in the total sample and in those with higher stroke risk (n=31). Study 2 (Nakhla et al., 2021) investigated if the relationship between self-reported SCD and objective cognition varies as a function of ethnicity [Hispanics/Latinos (N= 35) vs NHWs (N= 48)]. Higher self-reported SCD was associated with lower global cognition in Hispanics/Latinos, but not in NHWs. Study 3 (Nakhla et al., 2021) investigated the relationship between informant-reported SCD and objective cognition in a confirmed neurodegenerative disease sample, i.e., PD, (N= 139). Higher informant-reported SCD was significantly associated with poorer objective cognition (attention, learning, delayed recall, executive function).Collectively, these studies contributed to the literature by further characterizing SCD in three different and understudied older adult samples at risk for dementia: mostly NHWs, Hispanics/Latinos, and neurodegenerative disease (i.e., PD). Findings inform clinical practice by advancing our understanding of how SCD relates to objective cognition in different samples and provide evidence that SCD is related to early risk markers of dementia.
일반주제명  
Clinical psychology
일반주제명  
Neurosciences
일반주제명  
Psychobiology
일반주제명  
Aging
일반주제명  
Cognitive psychology
키워드  
Alzheimer's disease
키워드  
Memory
키워드  
Neuropsychology
키워드  
Objective cognition
키워드  
Subjective cognitive decline
기타저자  
University of California, San Diego Clinical Psychology (Joint Doctoral with SDSU)
기본자료저록  
Dissertations Abstracts International. 86-03B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aNakhla,  Marina  Zaher.
■24510▼aThe  Relationship  Between  Subjective  Cognitive  Decline  and  Objective  Cognitive  Performance  Within  Three  Different  Older  Adult  Samples
■260    ▼a[Sl]▼bUniversity  of  California,  San  Diego▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a141  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-03,  Section:  B.
■500    ▼aAdvisor:  Zlatar,  Zvinka  Z.;Schiehser,  Dawn  M.
■5021  ▼aThesis  (Ph.D.)--University  of  California,  San  Diego,  2024.
■520    ▼aOlder  adults,  including  Non-Hispanic  Whites  (NHWs),  Hispanics/Latinos,  and  those  with  neurodegenerative  diseases  (e.g.,  Parkinson's  Disease:  PD),  are  at  risk  for  dementia.  Subjective  cognitive  decline  (SCD;  perceived  cognitive  difficulties)  may  be  an  early  risk  marker  of  dementia.  However,  its  neural  correlates  and  utility  to  predict  concurrent  objective  cognition  across  these  different  risk  groups  remain  understudied.  This  3-paper  dissertation  investigated  associations  of  SCD  with  concurrent  objective  cognition  across  older  adults  at  risk  for  dementia:  1)  mostly  NHWs  (87%  Caucasian)  (age=  72.90),  2)  Hispanics/Latinos  (age=  73.97)  versus  NHWs  (age=  71.81),  and  3)  PD  (age=  67.56).  Study  2  augmented  Study  1  by  examining  ethnic  differences  in  SCD  reporting  between  NHWs  and  Hispanics/Latinos,  while  Study  3  expanded  findings  to  neurodegenerative  disease.  Archival  data  was  used  from  the  UCSD  WISE  Lab,  Shiley  Marcos  Alzheimer's  Disease  Research  Center,  and  VA  San  Diego  Healthcare  System.Study  1  (Nakhla  et  al.,  2024)  investigated  the  relationship  of  self-reported  SCD  with  objective  cognition  and  cerebral  blood  flow  (CBF)  in  a  cognitively  normal  sample  (N=52)  with  varying  stroke  risk  status.  Greater  SCD  severity  was  significantly  associated  with  lower  memory  and  entorhinal  CBF  in  the  total  sample  and  in  those  with  higher  stroke  risk  (n=31).  Study  2  (Nakhla  et  al.,  2021)  investigated  if  the  relationship  between  self-reported  SCD  and  objective  cognition  varies  as  a  function  of  ethnicity  [Hispanics/Latinos  (N=  35)  vs  NHWs  (N=  48)].  Higher  self-reported  SCD  was  associated  with  lower  global  cognition  in  Hispanics/Latinos,  but  not  in  NHWs.  Study  3  (Nakhla  et  al.,  2021)  investigated  the  relationship  between  informant-reported  SCD  and  objective  cognition  in  a  confirmed  neurodegenerative  disease  sample,  i.e.,  PD,  (N=  139).  Higher  informant-reported  SCD  was  significantly  associated  with  poorer  objective  cognition  (attention,  learning,  delayed  recall,  executive  function).Collectively,  these  studies  contributed  to  the  literature  by  further  characterizing  SCD  in  three  different  and  understudied  older  adult  samples  at  risk  for  dementia:  mostly  NHWs,  Hispanics/Latinos,  and  neurodegenerative  disease  (i.e.,  PD).  Findings  inform  clinical  practice  by  advancing  our  understanding  of  how  SCD  relates  to  objective  cognition  in  different  samples  and  provide  evidence  that  SCD  is  related  to  early  risk  markers  of  dementia.
■590    ▼aSchool  code:  0033.
■650  4▼aClinical  psychology
■650  4▼aNeurosciences
■650  4▼aPsychobiology
■650  4▼aAging
■650  4▼aCognitive  psychology
■653    ▼aAlzheimer's  disease
■653    ▼aMemory
■653    ▼aNeuropsychology
■653    ▼aObjective  cognition
■653    ▼aSubjective  cognitive  decline
■690    ▼a0622
■690    ▼a0349
■690    ▼a0317
■690    ▼a0633
■690    ▼a0493
■71020▼aUniversity  of  California,  San  Diego▼bClinical  Psychology  (Joint  Doctoral  with  SDSU).
■7730  ▼tDissertations  Abstracts  International▼g86-03B.
■790    ▼a0033
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17160103▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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