본문

서브메뉴

Decision Sciences, Health, and Equity: Applications and Methods for Kidney Allocation and Infectious Diseases
Decision Sciences, Health, and Equity: Applications and Methods for Kidney Allocation and ...
Decision Sciences, Health, and Equity: Applications and Methods for Kidney Allocation and Infectious Diseases

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20250211152121
ISBN  
9798384336143
DDC  
616
저자명  
Kaufmann, Matthew Brandon.
서명/저자  
Decision Sciences, Health, and Equity: Applications and Methods for Kidney Allocation and Infectious Diseases
발행사항  
[Sl] : Stanford University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
147 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-03, Section: B.
주기사항  
Advisor: Goldhaber-Fiebert, Jeremy.
학위논문주기  
Thesis (Ph.D.)--Stanford University, 2024.
초록/해제  
요약The field of decision sciences has the potential to make lasting impacts on health and equity. In kidney transplantation, older candidates are harmed by our current kidney allocation system because the system incentivizes transplanting healthier candidates with higher-quality kidneys. Helicobacter pylori (H. pylori) is the strongest known risk factor for gastric cancer, and there are large racial and ethnic disparities in prevalence in the United States. My dissertation focuses on decision science methods and applications that address these inequalities. In my first chapter, I developed and calibrated a microsimulation model of the kidney transplant process for older adults in the United States. After calibration, the model was able to accurately replicate the transplant process. I found that receiving an imperfect but transplant-quality deceased donor kidney results in longer life expectancy than remaining on dialysis. The second chapter uses the calibrated model from my first chapter to simulate policy options that make use of imperfect but transplant-quality donor kidneys that would otherwise go unused. Allowing older candidates access to any available and usable kidneys is estimated to be cost-effective from the healthcare sector perspective and cost-saving from the societal perspective. For my third chapter, I proposed a new method for estimating Who-Acquired-Infection-From-Whom (WAIFW) matrix parameters with multiple levels of stratification. The method allows modelers to capture heterogeneous mixing patterns. We demonstrate that in the context of H. pylori, an assortative mixing assumption will underestimate the impact of policies compared to a proportional mixing assumption. My research develops and applies decision sciences methods to the fields of kidney transplantation and H. pylorifocusing on heterogeneities in these populations. This work has implications for health outcomes and equity in both the general population as well as underserved populations.
일반주제명  
Hemodialysis
일반주제명  
Infectious diseases
일반주제명  
Patients
일반주제명  
Quality of life
일반주제명  
Diabetes
일반주제명  
Life expectancy
일반주제명  
Mortality
일반주제명  
Kidney diseases
일반주제명  
Decision making
일반주제명  
Kidney transplants
일반주제명  
Ethnicity
일반주제명  
Disease transmission
일반주제명  
Ethnic studies
일반주제명  
Health sciences
일반주제명  
Medical ethics
일반주제명  
Medicine
일반주제명  
Public health
일반주제명  
Statistics
일반주제명  
Surgery
기타저자  
Stanford University.
기본자료저록  
Dissertations Abstracts International. 86-03B.
전자적 위치 및 접속  
로그인 후 원문을 볼 수 있습니다.

MARC

 008250123s2024        us                              c    eng  d
■001000017162993
■00520250211152121
■006m          o    d                
■007cr#unu||||||||
■020    ▼a9798384336143
■035    ▼a(MiAaPQ)AAI31460393
■035    ▼a(MiAaPQ)Stanfordzx681xd2068
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a616
■1001  ▼aKaufmann,  Matthew  Brandon.
■24510▼aDecision  Sciences,  Health,  and  Equity:  Applications  and  Methods  for  Kidney  Allocation  and  Infectious  Diseases
■260    ▼a[Sl]▼bStanford  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a147  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-03,  Section:  B.
■500    ▼aAdvisor:  Goldhaber-Fiebert,  Jeremy.
■5021  ▼aThesis  (Ph.D.)--Stanford  University,  2024.
■520    ▼aThe  field  of  decision  sciences  has  the  potential  to  make  lasting  impacts  on  health  and  equity.  In  kidney  transplantation,  older  candidates  are  harmed  by  our  current  kidney  allocation  system  because  the  system  incentivizes  transplanting  healthier  candidates  with  higher-quality  kidneys.  Helicobacter  pylori  (H.  pylori)  is  the  strongest  known  risk  factor  for  gastric  cancer,  and  there  are  large  racial  and  ethnic  disparities  in  prevalence  in  the  United  States.  My  dissertation  focuses  on  decision  science  methods  and  applications  that  address  these  inequalities.  In  my  first  chapter,  I  developed  and  calibrated  a  microsimulation  model  of  the  kidney  transplant  process  for  older  adults  in  the  United  States.  After  calibration,  the  model  was  able  to  accurately  replicate  the  transplant  process.  I  found  that  receiving  an  imperfect  but  transplant-quality  deceased  donor  kidney  results  in  longer  life  expectancy  than  remaining  on  dialysis.  The  second  chapter  uses  the  calibrated  model  from  my  first  chapter  to  simulate  policy  options  that  make  use  of  imperfect  but  transplant-quality  donor  kidneys  that  would  otherwise  go  unused.  Allowing  older  candidates  access  to  any  available  and  usable  kidneys  is  estimated  to  be  cost-effective  from  the  healthcare  sector  perspective  and  cost-saving  from  the  societal  perspective.  For  my  third  chapter,  I  proposed  a  new  method  for  estimating  Who-Acquired-Infection-From-Whom  (WAIFW)  matrix  parameters  with  multiple  levels  of  stratification.  The  method  allows  modelers  to  capture  heterogeneous  mixing  patterns.  We  demonstrate  that  in  the  context  of  H.  pylori,  an  assortative  mixing  assumption  will  underestimate  the  impact  of  policies  compared  to  a  proportional  mixing  assumption.  My  research  develops  and  applies  decision  sciences  methods  to  the  fields  of  kidney  transplantation  and  H.  pylorifocusing  on  heterogeneities  in  these  populations.  This  work  has  implications  for  health  outcomes  and  equity  in  both  the  general  population  as  well  as  underserved  populations.
■590    ▼aSchool  code:  0212.
■650  4▼aHemodialysis
■650  4▼aInfectious  diseases
■650  4▼aPatients
■650  4▼aQuality  of  life
■650  4▼aDiabetes
■650  4▼aLife  expectancy
■650  4▼aMortality
■650  4▼aKidney  diseases
■650  4▼aDecision  making
■650  4▼aKidney  transplants
■650  4▼aEthnicity
■650  4▼aDisease  transmission
■650  4▼aEthnic  studies
■650  4▼aHealth  sciences
■650  4▼aMedical  ethics
■650  4▼aMedicine
■650  4▼aPublic  health
■650  4▼aStatistics
■650  4▼aSurgery
■690    ▼a0631
■690    ▼a0769
■690    ▼a0566
■690    ▼a0497
■690    ▼a0564
■690    ▼a0573
■690    ▼a0463
■690    ▼a0576
■71020▼aStanford  University.
■7730  ▼tDissertations  Abstracts  International▼g86-03B.
■790    ▼a0212
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17162993▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

미리보기

내보내기

chatGPT토론

Ai 추천 관련 도서


    신착도서 더보기
    최근 3년간 통계입니다.

    소장정보

    • 예약
    • 소재불명신고
    • 나의폴더
    • 우선정리요청
    • 비도서대출신청
    • 야간 도서대출신청
    소장자료
    등록번호 청구기호 소장처 대출가능여부 대출정보
    TF10542 전자도서 대출가능 마이폴더 부재도서신고 비도서대출신청 야간 도서대출신청

    * 대출중인 자료에 한하여 예약이 가능합니다. 예약을 원하시면 예약버튼을 클릭하십시오.

    해당 도서를 다른 이용자가 함께 대출한 도서

    관련 인기도서

    로그인 후 이용 가능합니다.