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Emerging and Re-emerging Infectious Diseases and Their Social Contexts
Emerging and Re-emerging Infectious Diseases and Their Social Contexts
Emerging and Re-emerging Infectious Diseases and Their Social Contexts

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자료유형  
 학위논문 서양
최종처리일시  
20250211151450
ISBN  
9798382810690
DDC  
312
저자명  
Klein, Jordan D.
서명/저자  
Emerging and Re-emerging Infectious Diseases and Their Social Contexts
발행사항  
[Sl] : Princeton University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
422 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-04, Section: B.
주기사항  
Advisor: Goldman, Noreen.
학위논문주기  
Thesis (Ph.D.)--Princeton University, 2024.
초록/해제  
요약This dissertation explores contemporary challenges in re-/emerging infectious diseases and their social drivers and impacts, focusing on the COVID-19 pandemic and the infectious disease consequences of climate change.Chapter I presents the first multidecade climate-mortality study of a non-South African sub-Saharan African city, concentrating on enteric infectious diseases in Antananarivo, Madagascar. Utilizing vital registration data and non-parametric models, I reveal an increasing risk of mortality following heavy rainfall events over time. Given the anticipated increase in frequency and severity of such events due to climate change, these findings underscore the vulnerability of Antananarivo to mortality from re-emerging climate-sensitive diseases.In Chapter II, I analyze the impact of COVID-19-related travel restrictions on migration, focusing on migrants from North and West Africa. Employing digital trace data and dynamic linear panel models, I uncover a paradoxical increase in migrants in countries implementing these restrictions. This suggests that a commonly-used set of pandemic-response policies may be ineffective in achieving their intended goals, highlighting the need for effective policies that take the needs of migrants into account.Finally, Chapter III uses mechanistic epidemiological models to address the empirical challenge of disentangling the roles of interventions like social distancing and vaccination from pre-existing social conditions in the production of COVID-19 mortality gradients in Brazil, arising from a lack of counterfactual evidence from a scenario in which no interventions were implemented to control its spread. This is the first study to incorporate novel theoretical frameworks dissecting the pathways contributing to social gradients in emerging infectious disease mortality into mechanistic epidemiological models, and the first to model the socio-economic drivers of COVID mortality inequalities in Brazil on a national scale, with geospatial specificity, while utilizing real-world data-informed parameters. Parameterizing the model using census, survey, death registration, epidemiological surveillance, and digital trace data, I find that pre-existing social inequities were most responsible for producing COVID-19 mortality disparities, which were further exacerbated by unequally implemented interventions. However, the impacts of these pre-existing inequities could have been counteracted by intervention strategies prioritizing the most disadvantaged. These findings offer insights that could inform more equitable responses to future infectious disease epidemics.
일반주제명  
Demography
일반주제명  
Epidemiology
일반주제명  
Climate change
키워드  
Computational social science
키워드  
COVID-19
키워드  
Infectious disease
키워드  
Migration and mobility
키워드  
Mortality
기타저자  
Princeton University Population Studies
기본자료저록  
Dissertations Abstracts International. 86-04B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aKlein,  Jordan  D.▼0(orcid)0000-0001-5417-1647
■24510▼aEmerging  and  Re-emerging  Infectious  Diseases  and  Their  Social  Contexts
■260    ▼a[Sl]▼bPrinceton  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a422  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-04,  Section:  B.
■500    ▼aAdvisor:  Goldman,  Noreen.
■5021  ▼aThesis  (Ph.D.)--Princeton  University,  2024.
■520    ▼aThis  dissertation  explores  contemporary  challenges  in  re-/emerging  infectious  diseases  and  their  social  drivers  and  impacts,  focusing  on  the  COVID-19  pandemic  and  the  infectious  disease  consequences  of  climate  change.Chapter  I  presents  the  first  multidecade  climate-mortality  study  of  a  non-South  African  sub-Saharan  African  city,  concentrating  on  enteric  infectious  diseases  in  Antananarivo,  Madagascar.  Utilizing  vital  registration  data  and  non-parametric  models,  I  reveal  an  increasing  risk  of  mortality  following  heavy  rainfall  events  over  time.  Given  the  anticipated  increase  in  frequency  and  severity  of  such  events  due  to  climate  change,  these  findings  underscore  the  vulnerability  of  Antananarivo  to  mortality  from  re-emerging  climate-sensitive  diseases.In  Chapter  II,  I  analyze  the  impact  of  COVID-19-related  travel  restrictions  on  migration,  focusing  on  migrants  from  North  and  West  Africa.  Employing  digital  trace  data  and  dynamic  linear  panel  models,  I  uncover  a  paradoxical  increase  in  migrants  in  countries  implementing  these  restrictions.  This  suggests  that  a  commonly-used  set  of  pandemic-response  policies  may  be  ineffective  in  achieving  their  intended  goals,  highlighting  the  need  for  effective  policies  that  take  the  needs  of  migrants  into  account.Finally,  Chapter  III  uses  mechanistic  epidemiological  models  to  address  the  empirical  challenge  of  disentangling  the  roles  of  interventions  like  social  distancing  and  vaccination  from  pre-existing  social  conditions  in  the  production  of  COVID-19  mortality  gradients  in  Brazil,  arising  from  a  lack  of  counterfactual  evidence  from  a  scenario  in  which  no  interventions  were  implemented  to  control  its  spread.  This  is  the  first  study  to  incorporate  novel  theoretical  frameworks  dissecting  the  pathways  contributing  to  social  gradients  in  emerging  infectious  disease  mortality  into  mechanistic  epidemiological  models,  and  the  first  to  model  the  socio-economic  drivers  of  COVID  mortality  inequalities  in  Brazil  on  a  national  scale,  with  geospatial  specificity,  while  utilizing  real-world  data-informed  parameters.  Parameterizing  the  model  using  census,  survey,  death  registration,  epidemiological  surveillance,  and  digital  trace  data,  I  find  that  pre-existing  social  inequities  were  most  responsible  for  producing  COVID-19  mortality  disparities,  which  were  further  exacerbated  by  unequally  implemented  interventions.  However,  the  impacts  of  these  pre-existing  inequities  could  have  been  counteracted  by  intervention  strategies  prioritizing  the  most  disadvantaged.  These  findings  offer  insights  that  could  inform  more  equitable  responses  to  future  infectious  disease  epidemics.
■590    ▼aSchool  code:  0181.
■650  4▼aDemography
■650  4▼aEpidemiology
■650  4▼aClimate  change
■653    ▼aComputational  social  science
■653    ▼aCOVID-19
■653    ▼aInfectious  disease
■653    ▼aMigration  and  mobility
■653    ▼aMortality
■690    ▼a0938
■690    ▼a0766
■690    ▼a0404
■71020▼aPrinceton  University▼bPopulation  Studies.
■7730  ▼tDissertations  Abstracts  International▼g86-04B.
■790    ▼a0181
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17161823▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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