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Cognitive-affective Correlates of Pediatric Food Intake: Neural Food cue Reactivity and Reward-Related Decision-Making
Cognitive-affective Correlates of Pediatric Food Intake: Neural Food cue Reactivity and Re...
Cognitive-affective Correlates of Pediatric Food Intake: Neural Food cue Reactivity and Reward-Related Decision-Making

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자료유형  
 학위논문 서양
최종처리일시  
20250211152112
ISBN  
9798384211495
DDC  
641.555
저자명  
Fuchs, Bari Allison.
서명/저자  
Cognitive-affective Correlates of Pediatric Food Intake: Neural Food cue Reactivity and Reward-Related Decision-Making
발행사항  
[Sl] : The Pennsylvania State University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
258 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-03, Section: B.
주기사항  
Advisor: Keller, Kathleen L.
학위논문주기  
Thesis (Ph.D.)--The Pennsylvania State University, 2024.
초록/해제  
요약Between 2017 and 2020, over 20% of children in the United States had obesity. As diet and behavioral interventions to treat and prevent obesity are ineffective or produce small and variable effects, a better understanding of the factors that facilitate increased energy intake is needed. Theoretical models posit that psychological, physiological, and neural responses to food cues (i.e., food cue reactivity) and reward-related decision-making (RRDM) promote overeating and susceptibility to obesity in the present-day food environment. These theories are supported by research showing behavioral and neural responses to food cues are associated with eating behaviors and weight gain, and reward learning, executive functioning, and decision-making are altered in obesity. Nevertheless, it remains unclear how food cue reactivity and RRDM relate to pediatric eating behaviors. Therefore, this dissertation examined how neural responses to food cues (chapters 2 and 3) and decision-making processes (chapter 4) relate to laboratory-assessed food intake in children.To shed light on the mechanisms that increase intake in response to large portions of food (i.e., the portion size effect; PSE), chapter 2 examined neural responses to food and non-food (office supplies) images presented in larger and smaller (i.e., age-appropriate) amounts. On average, neural responses to amount (larger vs. smaller) were stronger but less extensive in visual processing areas for foods relative to office supplies. Neural responses to food energy density (kcal/g; higher vs. lower) differed in extent between larger and smaller amounts in regions implicated in value-based decision-making (orbitofrontal cortex, ventromedial prefrontal cortex). These results highlight potentially distinct neural pathways for encoding food energy content and quantity.To build on chapter 2, chapter 3 examined how neural responses to food portion size cues relate to children's susceptibility to the PSE. To do so, neural responses to food amount (larger vs. smaller) were regressed on individual-level linear and quadratic relationships between intake and portion size, estimated from children's intake data at four meals that varied in portion size. Relationships were examined within the appetitive network and cerebellum to extend prior work examining these associations in reward- and control-related brain regions. Response to food amount in cerebellar lobules IV-VI was negatively associated with the quadratic portion size slope; greater activation to larger portions was associated with smaller increases or larger decreases in intake as portions got larger, while greater activation to smaller portions was associated with greater increases in intake as portions got larger. Neural responses within the appetitive network were not associated with linear or quadratic portion size slopes. These results suggest decreased cerebellar activation in response larger amounts of food may increase children's susceptibility to overeating when faced with "supersized" portions of food.While chapters 2 and 3 shed light on the neural correlates of the PSE, they did not elucidate specific cognitive or affective processes that drive eating behaviors. Therefore, chapter 4 examined the relationships between decision-making processes and food intake in children. Decision-making was assessed with a task where children make selections with unknown reward outcomes, and decision-making processes were quantified with a reinforcement learning model. Food intake was measured with three paradigms: (1) a standard ad libitummeal, (2) an eating in the absence of hunger (EAH) protocol, and (3) a palatable buffet meal.
일반주제명  
Meals
일반주제명  
Photographs
일반주제명  
Fruits
일반주제명  
Body mass index
일반주제명  
Eating behavior
일반주제명  
Magnetic resonance imaging
일반주제명  
Decision making
일반주제명  
Obesity
일반주제명  
Behavioral psychology
일반주제명  
Health sciences
일반주제명  
Medical imaging
일반주제명  
Pediatrics
일반주제명  
Public health
기타저자  
The Pennsylvania State University.
기본자료저록  
Dissertations Abstracts International. 86-03B.
전자적 위치 및 접속  
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■1001  ▼aFuchs,  Bari  Allison.
■24510▼aCognitive-affective  Correlates  of  Pediatric  Food  Intake:  Neural  Food  cue  Reactivity  and  Reward-Related  Decision-Making
■260    ▼a[Sl]▼bThe  Pennsylvania  State  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a258  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-03,  Section:  B.
■500    ▼aAdvisor:  Keller,  Kathleen  L.
■5021  ▼aThesis  (Ph.D.)--The  Pennsylvania  State  University,  2024.
■520    ▼aBetween  2017  and  2020,  over  20%  of  children  in  the  United  States  had  obesity.  As  diet  and  behavioral  interventions  to  treat  and  prevent  obesity  are  ineffective  or  produce  small  and  variable  effects,  a  better  understanding  of  the  factors  that  facilitate  increased  energy  intake  is  needed.  Theoretical  models  posit  that  psychological,  physiological,  and  neural  responses  to  food  cues  (i.e.,  food  cue  reactivity)  and  reward-related  decision-making  (RRDM)  promote  overeating  and  susceptibility  to  obesity  in  the  present-day  food  environment.  These  theories  are  supported  by  research  showing  behavioral  and  neural  responses  to  food  cues  are  associated  with  eating  behaviors  and  weight  gain,  and  reward  learning,  executive  functioning,  and  decision-making  are  altered  in  obesity.  Nevertheless,  it  remains  unclear  how  food  cue  reactivity  and  RRDM  relate  to  pediatric  eating  behaviors.  Therefore,  this  dissertation  examined  how  neural  responses  to  food  cues  (chapters  2  and  3)  and  decision-making  processes  (chapter  4)  relate  to  laboratory-assessed  food  intake  in  children.To  shed  light  on  the  mechanisms  that  increase  intake  in  response  to  large  portions  of  food  (i.e.,  the  portion  size  effect;  PSE),  chapter  2  examined  neural  responses  to  food  and  non-food  (office  supplies)  images  presented  in  larger  and  smaller  (i.e.,  age-appropriate)  amounts.  On  average,  neural  responses  to  amount  (larger  vs.  smaller)  were  stronger  but  less  extensive  in  visual  processing  areas  for  foods  relative  to  office  supplies.  Neural  responses  to  food  energy  density  (kcal/g;  higher  vs.  lower)  differed  in  extent  between  larger  and  smaller  amounts  in  regions  implicated  in  value-based  decision-making  (orbitofrontal  cortex,  ventromedial  prefrontal  cortex).  These  results  highlight  potentially  distinct  neural  pathways  for  encoding  food  energy  content  and  quantity.To  build  on  chapter  2,  chapter  3  examined  how  neural  responses  to  food  portion  size  cues  relate  to  children's  susceptibility  to  the  PSE.  To  do  so,  neural  responses  to  food  amount  (larger  vs.  smaller)  were  regressed  on  individual-level  linear  and  quadratic  relationships  between  intake  and  portion  size,  estimated  from  children's  intake  data  at  four  meals  that  varied  in  portion  size.  Relationships  were  examined  within  the  appetitive  network  and  cerebellum  to  extend  prior  work  examining  these  associations  in  reward-  and  control-related  brain  regions.  Response  to  food  amount  in  cerebellar  lobules  IV-VI  was  negatively  associated  with  the  quadratic  portion  size  slope;  greater  activation  to  larger  portions  was  associated  with  smaller  increases  or  larger  decreases  in  intake  as  portions  got  larger,  while  greater  activation  to  smaller  portions  was  associated  with  greater  increases  in  intake  as  portions  got  larger.  Neural  responses  within  the  appetitive  network  were  not  associated  with  linear  or  quadratic  portion  size  slopes.  These  results  suggest  decreased  cerebellar  activation  in  response  larger  amounts  of  food  may  increase  children's  susceptibility  to  overeating  when  faced  with  "supersized"  portions  of  food.While  chapters  2  and  3  shed  light  on  the  neural  correlates  of  the  PSE,  they  did  not  elucidate  specific  cognitive  or  affective  processes  that  drive  eating  behaviors.  Therefore,  chapter  4  examined  the  relationships  between  decision-making  processes  and  food  intake  in  children.  Decision-making  was  assessed  with  a  task  where  children  make  selections  with  unknown  reward  outcomes,  and  decision-making  processes  were  quantified  with  a  reinforcement  learning  model.  Food  intake  was  measured  with  three  paradigms:  (1)  a  standard    ad  libitummeal,  (2)  an  eating  in  the  absence  of  hunger  (EAH)  protocol,  and  (3)  a  palatable  buffet  meal.
■590    ▼aSchool  code:  0176.
■650  4▼aMeals
■650  4▼aPhotographs
■650  4▼aFruits
■650  4▼aBody  mass  index
■650  4▼aEating  behavior
■650  4▼aMagnetic  resonance  imaging
■650  4▼aDecision  making
■650  4▼aObesity
■650  4▼aBehavioral  psychology
■650  4▼aHealth  sciences
■650  4▼aMedical  imaging
■650  4▼aPediatrics
■650  4▼aPublic  health
■690    ▼a0384
■690    ▼a0566
■690    ▼a0574
■690    ▼a0767
■690    ▼a0573
■71020▼aThe  Pennsylvania  State  University.
■7730  ▼tDissertations  Abstracts  International▼g86-03B.
■790    ▼a0176
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17162922▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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