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Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries
Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Benefic...
Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries

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자료유형  
 학위논문 서양
최종처리일시  
20250211151022
ISBN  
9798383165287
DDC  
614.4
저자명  
Perry, Allison.
서명/저자  
Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries
발행사항  
[Sl] : New York University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
157 p
주기사항  
Source: Dissertations Abstracts International, Volume: 85-12, Section: B.
주기사항  
Advisor: Cerda, Magdalena;Krawczyk, Noa.
학위논문주기  
Thesis (Ph.D.)--New York University, 2024.
초록/해제  
요약In the context of the ongoing opioid overdose crisis in the United States (US), the intersection of chronic pain, which affects one in five adults, and opioid use disorder (OUD), which directly impacts 1 in 7 US adults, poses significant clinical and public health challenges. These challenges are particularly pronounced among Medicaid beneficiaries, who face socioeconomic disparities and disproportionately high rates of both conditions. In this dissertation, we leverage administrative Medicaid claims data, which cover 40% of non-elderly individuals with OUD. We investigate the hypotheses that Medicaid patients with comorbid chronic pain and OUD face significant disparities in treatment access and health outcomes, further complicated by initial pain management practices that may inadvertently heighten the risk of developing OUD. First, we examine disparities in access to medication for opioid use disorder (MOUD) among New York State Medicaid beneficiaries with comorbid chronic pain and OUD. Using interrupted time series analyses, we examine MOUD treatment patterns among this population before and during the COVID-19 pandemic, when flexible MOUD policies were enacted. Next, as COVID-19 persists and evolves in society, we employ a propensity score matching approach within a target trial emulation framework to determine whether chronic pain and OUD increase the risk of several COVID-19 complications, and whether treating OUD alters this risk. Finally, we explore how initial pain management practices, including opioid prescribing and physical therapy, impact the risk of developing OUD. Using Poisson regression modeling techniques, we assess the incremental risk of OUD associated with varying opioid dosages and durations; we also examine the effect of incorporating physical therapy into care to treat US Medicaid beneficiaries with musculoskeletal pain. Overall, this dissertation demonstrates that patients with comorbid chronic pain and OUD face disparities in OUD care and a heightened risk of adverse health outcomes from COVID-19. We also highlight the importance of careful decisions around initial opioid prescribing practices and the need for increased access to and utilization of alternative pain management strategies, given significant downstream effects associated with characteristics of the first opioid prescription. Collectively, these studies underscore the need to identify and implement safer pain management strategies to prevent OUD from developing among patients living with pain; further, findings highlight the importance of developing more equitable, evidence-based strategies to improve OUD treatment access and to allocate resources among patients with chronic pain who have already developed OUD.
일반주제명  
Epidemiology
일반주제명  
Pharmacology
일반주제명  
Clinical psychology
키워드  
Opioid use disorder
키워드  
Medication for opioid use disorder
키워드  
Chronic pain
키워드  
Medicaid beneficiaries
기타저자  
New York University Basic Medical Science
기본자료저록  
Dissertations Abstracts International. 85-12B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aPerry,  Allison.
■24510▼aNavigating  the  Intersection  of  Chronic  Pain  and  Opioid  Use  Disorder  Among  Medicaid  Beneficiaries
■260    ▼a[Sl]▼bNew  York  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a157  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-12,  Section:  B.
■500    ▼aAdvisor:  Cerda,  Magdalena;Krawczyk,  Noa.
■5021  ▼aThesis  (Ph.D.)--New  York  University,  2024.
■520    ▼aIn  the  context  of  the  ongoing  opioid  overdose  crisis  in  the  United  States  (US),  the  intersection  of  chronic  pain,  which  affects  one  in  five  adults,  and  opioid  use  disorder  (OUD),  which  directly  impacts  1  in  7  US  adults,  poses  significant  clinical  and  public  health  challenges.  These  challenges  are  particularly  pronounced  among  Medicaid  beneficiaries,  who  face  socioeconomic  disparities  and  disproportionately  high  rates  of  both  conditions.  In  this  dissertation,  we  leverage  administrative  Medicaid  claims  data,  which  cover  40%  of  non-elderly  individuals  with  OUD.  We  investigate  the  hypotheses  that  Medicaid  patients  with  comorbid  chronic  pain  and  OUD  face  significant  disparities  in  treatment  access  and  health  outcomes,  further  complicated  by  initial  pain  management  practices  that  may  inadvertently  heighten  the  risk  of  developing  OUD.  First,  we  examine  disparities  in  access  to  medication  for  opioid  use  disorder  (MOUD)  among  New  York  State  Medicaid  beneficiaries  with  comorbid  chronic  pain  and  OUD.  Using  interrupted  time  series  analyses,  we  examine  MOUD  treatment  patterns  among  this  population  before  and  during  the  COVID-19  pandemic,  when  flexible  MOUD  policies  were  enacted.  Next,  as  COVID-19  persists  and  evolves  in  society,  we  employ  a  propensity  score  matching  approach  within  a  target  trial  emulation  framework  to  determine  whether  chronic  pain  and  OUD  increase  the  risk  of  several  COVID-19  complications,  and  whether  treating  OUD  alters  this  risk.  Finally,  we  explore  how  initial  pain  management  practices,  including  opioid  prescribing  and  physical  therapy,  impact  the  risk  of  developing  OUD.  Using  Poisson  regression  modeling  techniques,  we  assess  the  incremental  risk  of  OUD  associated  with  varying  opioid  dosages  and  durations;  we  also  examine  the  effect  of  incorporating  physical  therapy  into  care  to  treat  US  Medicaid  beneficiaries  with  musculoskeletal  pain.  Overall,  this  dissertation  demonstrates  that  patients  with  comorbid  chronic  pain  and  OUD  face  disparities  in  OUD  care  and  a  heightened  risk  of  adverse  health  outcomes  from  COVID-19. We  also  highlight  the  importance  of  careful  decisions  around  initial  opioid  prescribing  practices  and  the  need  for  increased  access  to  and  utilization  of  alternative  pain  management  strategies,  given  significant  downstream  effects  associated  with  characteristics  of  the  first  opioid  prescription.  Collectively,  these  studies  underscore  the  need  to  identify  and  implement  safer  pain  management  strategies  to  prevent  OUD  from  developing  among  patients  living  with  pain;  further,  findings  highlight  the  importance  of  developing  more  equitable,  evidence-based  strategies  to  improve  OUD  treatment  access  and  to  allocate  resources  among  patients  with  chronic  pain  who  have  already  developed  OUD.
■590    ▼aSchool  code:  0146.
■650  4▼aEpidemiology
■650  4▼aPharmacology
■650  4▼aClinical  psychology
■653    ▼aOpioid  use  disorder
■653    ▼aMedication  for  opioid  use  disorder
■653    ▼aChronic  pain
■653    ▼aMedicaid  beneficiaries
■690    ▼a0766
■690    ▼a0622
■690    ▼a0419
■690    ▼a0769
■71020▼aNew  York  University▼bBasic  Medical  Science.
■7730  ▼tDissertations  Abstracts  International▼g85-12B.
■790    ▼a0146
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17160454▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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