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Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries
Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20250211151022
- ISBN
- 9798383165287
- DDC
- 614.4
- 저자명
- Perry, Allison.
- 서명/저자
- Navigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries
- 발행사항
- [Sl] : New York University, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 157 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-12, Section: B.
- 주기사항
- Advisor: Cerda, Magdalena;Krawczyk, Noa.
- 학위논문주기
- Thesis (Ph.D.)--New York University, 2024.
- 초록/해제
- 요약In the context of the ongoing opioid overdose crisis in the United States (US), the intersection of chronic pain, which affects one in five adults, and opioid use disorder (OUD), which directly impacts 1 in 7 US adults, poses significant clinical and public health challenges. These challenges are particularly pronounced among Medicaid beneficiaries, who face socioeconomic disparities and disproportionately high rates of both conditions. In this dissertation, we leverage administrative Medicaid claims data, which cover 40% of non-elderly individuals with OUD. We investigate the hypotheses that Medicaid patients with comorbid chronic pain and OUD face significant disparities in treatment access and health outcomes, further complicated by initial pain management practices that may inadvertently heighten the risk of developing OUD. First, we examine disparities in access to medication for opioid use disorder (MOUD) among New York State Medicaid beneficiaries with comorbid chronic pain and OUD. Using interrupted time series analyses, we examine MOUD treatment patterns among this population before and during the COVID-19 pandemic, when flexible MOUD policies were enacted. Next, as COVID-19 persists and evolves in society, we employ a propensity score matching approach within a target trial emulation framework to determine whether chronic pain and OUD increase the risk of several COVID-19 complications, and whether treating OUD alters this risk. Finally, we explore how initial pain management practices, including opioid prescribing and physical therapy, impact the risk of developing OUD. Using Poisson regression modeling techniques, we assess the incremental risk of OUD associated with varying opioid dosages and durations; we also examine the effect of incorporating physical therapy into care to treat US Medicaid beneficiaries with musculoskeletal pain. Overall, this dissertation demonstrates that patients with comorbid chronic pain and OUD face disparities in OUD care and a heightened risk of adverse health outcomes from COVID-19. We also highlight the importance of careful decisions around initial opioid prescribing practices and the need for increased access to and utilization of alternative pain management strategies, given significant downstream effects associated with characteristics of the first opioid prescription. Collectively, these studies underscore the need to identify and implement safer pain management strategies to prevent OUD from developing among patients living with pain; further, findings highlight the importance of developing more equitable, evidence-based strategies to improve OUD treatment access and to allocate resources among patients with chronic pain who have already developed OUD.
- 일반주제명
- Epidemiology
- 일반주제명
- Pharmacology
- 일반주제명
- Clinical psychology
- 키워드
- Chronic pain
- 기타저자
- New York University Basic Medical Science
- 기본자료저록
- Dissertations Abstracts International. 85-12B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■006m o d
■007cr#unu||||||||
■020 ▼a9798383165287
■035 ▼a(MiAaPQ)AAI30996630
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a614.4
■1001 ▼aPerry, Allison.
■24510▼aNavigating the Intersection of Chronic Pain and Opioid Use Disorder Among Medicaid Beneficiaries
■260 ▼a[Sl]▼bNew York University▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a157 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-12, Section: B.
■500 ▼aAdvisor: Cerda, Magdalena;Krawczyk, Noa.
■5021 ▼aThesis (Ph.D.)--New York University, 2024.
■520 ▼aIn the context of the ongoing opioid overdose crisis in the United States (US), the intersection of chronic pain, which affects one in five adults, and opioid use disorder (OUD), which directly impacts 1 in 7 US adults, poses significant clinical and public health challenges. These challenges are particularly pronounced among Medicaid beneficiaries, who face socioeconomic disparities and disproportionately high rates of both conditions. In this dissertation, we leverage administrative Medicaid claims data, which cover 40% of non-elderly individuals with OUD. We investigate the hypotheses that Medicaid patients with comorbid chronic pain and OUD face significant disparities in treatment access and health outcomes, further complicated by initial pain management practices that may inadvertently heighten the risk of developing OUD. First, we examine disparities in access to medication for opioid use disorder (MOUD) among New York State Medicaid beneficiaries with comorbid chronic pain and OUD. Using interrupted time series analyses, we examine MOUD treatment patterns among this population before and during the COVID-19 pandemic, when flexible MOUD policies were enacted. Next, as COVID-19 persists and evolves in society, we employ a propensity score matching approach within a target trial emulation framework to determine whether chronic pain and OUD increase the risk of several COVID-19 complications, and whether treating OUD alters this risk. Finally, we explore how initial pain management practices, including opioid prescribing and physical therapy, impact the risk of developing OUD. Using Poisson regression modeling techniques, we assess the incremental risk of OUD associated with varying opioid dosages and durations; we also examine the effect of incorporating physical therapy into care to treat US Medicaid beneficiaries with musculoskeletal pain. Overall, this dissertation demonstrates that patients with comorbid chronic pain and OUD face disparities in OUD care and a heightened risk of adverse health outcomes from COVID-19. We also highlight the importance of careful decisions around initial opioid prescribing practices and the need for increased access to and utilization of alternative pain management strategies, given significant downstream effects associated with characteristics of the first opioid prescription. Collectively, these studies underscore the need to identify and implement safer pain management strategies to prevent OUD from developing among patients living with pain; further, findings highlight the importance of developing more equitable, evidence-based strategies to improve OUD treatment access and to allocate resources among patients with chronic pain who have already developed OUD.
■590 ▼aSchool code: 0146.
■650 4▼aEpidemiology
■650 4▼aPharmacology
■650 4▼aClinical psychology
■653 ▼aOpioid use disorder
■653 ▼aMedication for opioid use disorder
■653 ▼aChronic pain
■653 ▼aMedicaid beneficiaries
■690 ▼a0766
■690 ▼a0622
■690 ▼a0419
■690 ▼a0769
■71020▼aNew York University▼bBasic Medical Science.
■7730 ▼tDissertations Abstracts International▼g85-12B.
■790 ▼a0146
■791 ▼aPh.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17160454▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


