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Problems in Variable Selection: False Discovery Rate Control and Variational Inference
Problems in Variable Selection: False Discovery Rate Control and Variational Inference
Problems in Variable Selection: False Discovery Rate Control and Variational Inference

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20250211151422
ISBN  
9798382777672
DDC  
310
저자명  
Lin, Buyu.
서명/저자  
Problems in Variable Selection: False Discovery Rate Control and Variational Inference
발행사항  
[Sl] : Harvard University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
316 p
주기사항  
Source: Dissertations Abstracts International, Volume: 85-12, Section: B.
주기사항  
Advisor: Liu, Jun.
학위논문주기  
Thesis (Ph.D.)--Harvard University, 2024.
초록/해제  
요약Variable selection plays a key role in modern high-dimensional statistics. This dissertation provides a comprehensive survey of theory and methods developed by the author and collaborators, with a specific focus on two areas: false discovery rate (FDR) control and Bayesian variable selection. In the domain of FDR control, we introduce a data-splitting method to asymptotically control the FDR while maintaining a high power. Furthermore, a Multiple Data Splitting (MDS) method is proposed to stabilize the selection result and boost the power. In Chapter 1, we apply both DS and MDS to the generalized linear models, which appear to be more robust in finite-sample cases compared to existing methods. Chapter 2 provides some following discussions regarding the proposed method and Chapter 3 compares the power of the proposed method with two existing methods: the model-X knockoff and Gaussian mirror. In terms of the Bayesian variable selection, the posterior is typically high-dimensional and analytically intractable. Exact inference methods based on sampling, such as Markov Chain Monte Carlo (MCMC), can encounter challenges related to mixing. Variational inference has emerged as an attractive alternative for approximating the posterior distribution. By recasting the sampling problem as an optimization problem, variational inference can significantly reduce computational time. In chapter 4, we apply the variational inference to group variable selection with spike-and-slab prior and propose an efficient parameter-expanded coordinate-ascent algorithm to obtain the optimal variational Bayes approximation. The proposed method has demonstrated good performance in both simulations and a real data example.
일반주제명  
Statistics
일반주제명  
Endocrinology
일반주제명  
Biostatistics
키워드  
Multiple Data Splitting
키워드  
False discovery rate
키워드  
Markov Chain Monte Carlo
키워드  
Variational inference
키워드  
FDR control
기타저자  
Harvard University Statistics
기본자료저록  
Dissertations Abstracts International. 85-12B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aLin,  Buyu.▼0(orcid)0009-0000-2569-3753
■24510▼aProblems  in  Variable  Selection:  False  Discovery  Rate  Control  and  Variational  Inference
■260    ▼a[Sl]▼bHarvard  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a316  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-12,  Section:  B.
■500    ▼aAdvisor:  Liu,  Jun.
■5021  ▼aThesis  (Ph.D.)--Harvard  University,  2024.
■520    ▼aVariable  selection  plays  a  key  role  in  modern  high-dimensional  statistics.  This  dissertation  provides  a  comprehensive  survey  of  theory  and  methods  developed  by  the  author  and  collaborators,  with  a  specific  focus  on  two  areas:  false  discovery  rate  (FDR)  control  and  Bayesian  variable  selection.  In  the  domain  of  FDR  control,  we  introduce  a  data-splitting  method  to  asymptotically  control  the  FDR  while  maintaining  a  high  power.  Furthermore,  a  Multiple  Data  Splitting  (MDS)  method  is  proposed  to  stabilize  the  selection  result  and  boost  the  power.  In  Chapter  1,  we  apply  both  DS  and  MDS  to  the  generalized  linear  models,  which  appear  to  be  more  robust  in  finite-sample  cases  compared  to  existing  methods.  Chapter  2  provides  some  following  discussions  regarding  the  proposed  method  and  Chapter  3  compares  the  power  of  the  proposed  method  with  two  existing  methods:  the  model-X  knockoff  and  Gaussian  mirror.  In  terms  of  the  Bayesian  variable  selection,  the  posterior  is  typically  high-dimensional  and  analytically  intractable.  Exact  inference  methods  based  on  sampling,  such  as  Markov  Chain  Monte  Carlo  (MCMC),  can  encounter  challenges  related  to  mixing.  Variational  inference  has  emerged  as  an  attractive  alternative  for  approximating  the  posterior  distribution.  By  recasting  the  sampling  problem  as  an  optimization  problem,  variational  inference  can  significantly  reduce  computational  time.  In  chapter  4,  we  apply  the  variational  inference  to  group  variable  selection  with  spike-and-slab  prior  and  propose  an  efficient  parameter-expanded  coordinate-ascent  algorithm  to  obtain  the  optimal  variational  Bayes  approximation.  The  proposed  method  has  demonstrated  good  performance  in  both  simulations  and  a  real  data  example.
■590    ▼aSchool  code:  0084.
■650  4▼aStatistics
■650  4▼aEndocrinology
■650  4▼aBiostatistics
■653    ▼aMultiple  Data  Splitting
■653    ▼aFalse  discovery  rate
■653    ▼aMarkov  Chain  Monte  Carlo
■653    ▼aVariational  inference
■653    ▼aFDR  control
■690    ▼a0463
■690    ▼a0409
■690    ▼a0308
■71020▼aHarvard  University▼bStatistics.
■7730  ▼tDissertations  Abstracts  International▼g85-12B.
■790    ▼a0084
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17161622▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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