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Scalable Computational Frameworks for Next-Generation Sequencing Analysis and Gene Set Integration
Scalable Computational Frameworks for Next-Generation Sequencing Analysis and Gene Set Int...
Scalable Computational Frameworks for Next-Generation Sequencing Analysis and Gene Set Integration

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자료유형  
 학위논문 서양
최종처리일시  
20250211151515
ISBN  
9798383607848
DDC  
574
저자명  
Abuelanin, Mohamed.
서명/저자  
Scalable Computational Frameworks for Next-Generation Sequencing Analysis and Gene Set Integration
발행사항  
[Sl] : University of California, Davis, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
85 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-02, Section: B.
주기사항  
Advisor: Brown, C. Titus.
학위논문주기  
Thesis (Ph.D.)--University of California, Davis, 2024.
초록/해제  
요약The rapid growth in biomedical research has generated vast amounts of data, including genomic, molecular, imaging, and clinical information from humans and other species. Leveraging this data is essential for groundbreaking scientific discoveries and a deeper understanding of health and disease across different species. However, the complexity and volume of these datasets present significant computational challenges, limiting their potential.This dissertation addresses two key challenges in biomedical data analysis: the efficient evaluation of sequencing data and the effective management and analysis of gene sets. By focusing on these areas, we develop innovative computational methods that enable the rapid, scalable, and accurate processing of large-scale biomedical data. For sequencing data, we create algorithms that enhance the speed and precision of data evaluation, making it feasible to manage the increasing volume of sequences generated by modern technologies. For gene sets, we devise tools for their efficient management and analysis, allowing researchers to draw meaningful insights from complex genetic information.Through this research, we aim to contribute to the development of new analytical tools and methods, ultimately supporting the advancement of precision medicine and personalized healthcare for both human and veterinary applications.
일반주제명  
Bioinformatics
일반주제명  
Computer science
일반주제명  
Biostatistics
일반주제명  
Molecular biology
키워드  
Alignment-free
키워드  
Coverage
키워드  
Gene sets
키워드  
K-mer-based
키워드  
Sequencing data
기타저자  
University of California, Davis Computer Science
기본자료저록  
Dissertations Abstracts International. 86-02B.
전자적 위치 및 접속  
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MARC

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■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a574
■1001  ▼aAbuelanin,  Mohamed.
■24510▼aScalable  Computational  Frameworks  for  Next-Generation  Sequencing  Analysis  and  Gene  Set  Integration
■260    ▼a[Sl]▼bUniversity  of  California,  Davis▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a85  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-02,  Section:  B.
■500    ▼aAdvisor:  Brown,  C.  Titus.
■5021  ▼aThesis  (Ph.D.)--University  of  California,  Davis,  2024.
■520    ▼aThe  rapid  growth  in  biomedical  research  has  generated  vast  amounts  of  data,  including  genomic,  molecular,  imaging,  and  clinical  information  from  humans  and  other  species.  Leveraging  this  data  is  essential  for  groundbreaking  scientific  discoveries  and  a  deeper  understanding  of  health  and  disease  across  different  species.  However,  the  complexity  and  volume  of  these  datasets  present  significant  computational  challenges,  limiting  their  potential.This  dissertation  addresses  two  key  challenges  in  biomedical  data  analysis:  the  efficient  evaluation  of  sequencing  data  and  the  effective  management  and  analysis  of  gene  sets.  By  focusing  on  these  areas,  we  develop  innovative  computational  methods  that  enable  the  rapid,  scalable,  and  accurate  processing  of  large-scale  biomedical  data.  For  sequencing  data,  we  create  algorithms  that  enhance  the  speed  and  precision  of  data  evaluation,  making  it  feasible  to  manage  the  increasing  volume  of  sequences  generated  by  modern  technologies.  For  gene  sets,  we  devise  tools  for  their  efficient  management  and  analysis,  allowing  researchers  to  draw  meaningful  insights  from  complex  genetic  information.Through  this  research,  we  aim  to  contribute  to  the  development  of  new  analytical  tools  and  methods,  ultimately  supporting  the  advancement  of  precision  medicine  and  personalized  healthcare  for  both  human  and  veterinary  applications.
■590    ▼aSchool  code:  0029.
■650  4▼aBioinformatics
■650  4▼aComputer  science
■650  4▼aBiostatistics
■650  4▼aMolecular  biology
■653    ▼aAlignment-free
■653    ▼aCoverage
■653    ▼aGene  sets
■653    ▼aK-mer-based
■653    ▼aSequencing  data
■690    ▼a0715
■690    ▼a0984
■690    ▼a0307
■690    ▼a0308
■71020▼aUniversity  of  California,  Davis▼bComputer  Science.
■7730  ▼tDissertations  Abstracts  International▼g86-02B.
■790    ▼a0029
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17162022▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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