서브메뉴
검색
Effects of Thoracic Endovascular Aortic Repair on Cardiac Function at Rest
Effects of Thoracic Endovascular Aortic Repair on Cardiac Function at Rest
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20250211151150
- ISBN
- 9798382321752
- DDC
- 610
- 저자명
- Kassam, Nabeel.
- 서명/저자
- Effects of Thoracic Endovascular Aortic Repair on Cardiac Function at Rest
- 발행사항
- [Sl] : Yale University, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 39 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 85-11, Section: B.
- 주기사항
- Advisor: Assi, Roland.
- 학위논문주기
- Thesis (M.D.)--Yale University, 2024.
- 초록/해제
- 요약a. Hypothesis: We hypothesize that Thoracic Endovascular Aortic Repair (TEVAR) leads to a decline in cardiac function among post-operative patients. Our primary objective is to identify the changes of cardiac function to post-TEVAR patients at rest using echocardiography studies. With this knowledge, we aim to gain valuable insight into the post-op management of patients with the goal of strategizing post-op care to reduce complications and exacerbation to heart failure.b. Methods: Chart review of the electronic medical record (EMR) was used to collect patient data, patient history, procedural information, outcomes, and echocardiogram parameters. To assess the impact of TEVAR, the echo parameters were then analyzed using a paired sample t-test, comparing pre-TEVAR and post-TEVAR echocardiograms. The alpha level for determining statistical significance was set at p=0.05 for two-sided comparisons.c. Results: Between the pre-TEVAR echo and first post-op echo, average indexed left atrial volume for all patients (n=30) was 35.68 pre-TEVAR and increased to 35.75 post-TEVAR with a p-value of 0.97. Mitral E/A ratio decreased from 1.09 pre-operatively to 1.04 post-operatively. E/A ratio (n=29) with a p-value of 0.92. Average E/e' ratio increased from 10.59 pre-TEVAR to 10.69 post-TEVAR (n=32) with a p-value of 0.91. Tricuspid regurgitation pressure gradient (TRPG) increased from 24.02 pre-operatively to 26.96 post-operatively (n=22) with a p-value of 0.33. Between the pre-TEVAR echo and second post-op echo, the indexed left atrial volume increased on average by 3.62 after TEVAR (p=0.66). E/A ratio decreased by 0.03 across all patients on average (p=0.66), while E/e' ratio decreased by 0.25 post-operatively (p=0.31). TRPG increased by 0.92 after TEVAR (p=0.84).d. Conclusions: The data showed a slight upwards trend in TRPG after the first post-op echo. However, no statistically significant changes to diastolic function were seen in patients after TEVAR.
- 일반주제명
- Medicine
- 일반주제명
- Physiology
- 일반주제명
- Surgery
- 키워드
- Aortic repair
- 키워드
- Cardiac function
- 기타저자
- Yale University Yale School of Medicine
- 기본자료저록
- Dissertations Abstracts International. 85-11B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
008250123s2024 us c eng d■001000017161016
■00520250211151150
■006m o d
■007cr#unu||||||||
■020 ▼a9798382321752
■035 ▼a(MiAaPQ)AAI31235402
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a610
■1001 ▼aKassam, Nabeel.
■24510▼aEffects of Thoracic Endovascular Aortic Repair on Cardiac Function at Rest
■260 ▼a[Sl]▼bYale University▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a39 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 85-11, Section: B.
■500 ▼aAdvisor: Assi, Roland.
■5021 ▼aThesis (M.D.)--Yale University, 2024.
■520 ▼aa. Hypothesis: We hypothesize that Thoracic Endovascular Aortic Repair (TEVAR) leads to a decline in cardiac function among post-operative patients. Our primary objective is to identify the changes of cardiac function to post-TEVAR patients at rest using echocardiography studies. With this knowledge, we aim to gain valuable insight into the post-op management of patients with the goal of strategizing post-op care to reduce complications and exacerbation to heart failure.b. Methods: Chart review of the electronic medical record (EMR) was used to collect patient data, patient history, procedural information, outcomes, and echocardiogram parameters. To assess the impact of TEVAR, the echo parameters were then analyzed using a paired sample t-test, comparing pre-TEVAR and post-TEVAR echocardiograms. The alpha level for determining statistical significance was set at p=0.05 for two-sided comparisons.c. Results: Between the pre-TEVAR echo and first post-op echo, average indexed left atrial volume for all patients (n=30) was 35.68 pre-TEVAR and increased to 35.75 post-TEVAR with a p-value of 0.97. Mitral E/A ratio decreased from 1.09 pre-operatively to 1.04 post-operatively. E/A ratio (n=29) with a p-value of 0.92. Average E/e' ratio increased from 10.59 pre-TEVAR to 10.69 post-TEVAR (n=32) with a p-value of 0.91. Tricuspid regurgitation pressure gradient (TRPG) increased from 24.02 pre-operatively to 26.96 post-operatively (n=22) with a p-value of 0.33. Between the pre-TEVAR echo and second post-op echo, the indexed left atrial volume increased on average by 3.62 after TEVAR (p=0.66). E/A ratio decreased by 0.03 across all patients on average (p=0.66), while E/e' ratio decreased by 0.25 post-operatively (p=0.31). TRPG increased by 0.92 after TEVAR (p=0.84).d. Conclusions: The data showed a slight upwards trend in TRPG after the first post-op echo. However, no statistically significant changes to diastolic function were seen in patients after TEVAR.
■590 ▼aSchool code: 0265.
■650 4▼aMedicine
■650 4▼aPhysiology
■650 4▼aSurgery
■653 ▼aAortic repair
■653 ▼aPost-operative patients
■653 ▼aCardiac function
■653 ▼aEndovascular repair
■653 ▼aThoracic Endovascular Aortic Repair
■690 ▼a0564
■690 ▼a0576
■690 ▼a0719
■71020▼aYale University▼bYale School of Medicine.
■7730 ▼tDissertations Abstracts International▼g85-11B.
■790 ▼a0265
■791 ▼aM.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17161016▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
