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Characterizing the Nonequilibrium Driving Forces Responsible for the Emergence of Life
Characterizing the Nonequilibrium Driving Forces Responsible for the Emergence of Life
Characterizing the Nonequilibrium Driving Forces Responsible for the Emergence of Life

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20250211151326
ISBN  
9798384058489
DDC  
574.191
저자명  
Kocher, Charles D.
서명/저자  
Characterizing the Nonequilibrium Driving Forces Responsible for the Emergence of Life
발행사항  
[Sl] : State University of New York at Stony Brook, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
303 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-03, Section: B.
주기사항  
Advisor: Dill, Ken A.
학위논문주기  
Thesis (Ph.D.)--State University of New York at Stony Brook, 2024.
초록/해제  
요약Uncovering the origin of life on earth remains a grand challenge problem for the natural sciences. Some headway has been made by reasoning about which biological macromolecules were the first to appear, as in the well-known "RNA world" hypothesis. However, new approaches are needed for further advances. We seek instead the physical driving forces, powered by nonequilibrium supplies of energy, that could have compelled the emergence of life from simple chemistry in the capricious environments of the early earth. This perspective leads us to examine the prebiotic origins and characteristics not of molecule types, but of the dynamical principles of self-organization, adaptation, and persistence. We find that evolutionary dynamics, biology's essential driving force, has a definitive, universal beginning. By focusing on how Darwinian evolution arises naturally in the protein folding process, we demonstrate how driving forces are the key to all coherent origin of life narratives.
일반주제명  
Biophysics
일반주제명  
Theoretical physics
일반주제명  
Evolution & development
키워드  
Cooperativity
키워드  
Evolution
키워드  
Fitness
키워드  
Origin of life
키워드  
Protein World
키워드  
Stochastic dynamics
기타저자  
State University of New York at Stony Brook Physics
기본자료저록  
Dissertations Abstracts International. 86-03B.
전자적 위치 및 접속  
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MARC

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■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a574.191
■1001  ▼aKocher,  Charles  D.
■24510▼aCharacterizing  the  Nonequilibrium  Driving  Forces  Responsible  for  the  Emergence  of  Life
■260    ▼a[Sl]▼bState  University  of  New  York  at  Stony  Brook▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a303  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-03,  Section:  B.
■500    ▼aAdvisor:  Dill,  Ken  A.
■5021  ▼aThesis  (Ph.D.)--State  University  of  New  York  at  Stony  Brook,  2024.
■520    ▼aUncovering  the  origin  of  life  on  earth  remains  a  grand  challenge  problem  for  the  natural  sciences.  Some  headway  has  been  made  by  reasoning  about  which  biological  macromolecules  were  the  first  to  appear,  as  in  the  well-known  "RNA  world"  hypothesis.  However,  new  approaches  are  needed  for  further  advances.  We  seek  instead  the  physical  driving  forces,  powered  by  nonequilibrium  supplies  of  energy,  that  could  have  compelled  the  emergence  of  life  from  simple  chemistry  in  the  capricious  environments  of  the  early  earth.  This  perspective  leads  us  to  examine  the  prebiotic  origins  and  characteristics  not  of  molecule  types,  but  of  the  dynamical  principles  of  self-organization,  adaptation,  and  persistence.  We  find  that  evolutionary  dynamics,  biology's  essential  driving  force,  has  a  definitive,  universal  beginning.  By  focusing  on  how  Darwinian  evolution  arises  naturally  in  the  protein  folding  process,  we  demonstrate  how  driving  forces  are  the  key  to  all  coherent  origin  of  life  narratives.
■590    ▼aSchool  code:  0771.
■650  4▼aBiophysics
■650  4▼aTheoretical  physics
■650  4▼aEvolution  &  development
■653    ▼aCooperativity
■653    ▼aEvolution
■653    ▼aFitness
■653    ▼aOrigin  of  life
■653    ▼aProtein  World
■653    ▼aStochastic  dynamics
■690    ▼a0786
■690    ▼a0753
■690    ▼a0412
■71020▼aState  University  of  New  York  at  Stony  Brook▼bPhysics.
■7730  ▼tDissertations  Abstracts  International▼g86-03B.
■790    ▼a0771
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17161222▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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