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Understanding the Nucleation and Growth of ZIF-8 Polymorphs
Understanding the Nucleation and Growth of ZIF-8 Polymorphs
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20250211151950
- ISBN
- 9798383596005
- DDC
- 540
- 서명/저자
- Understanding the Nucleation and Growth of ZIF-8 Polymorphs
- 발행사항
- [Sl] : University of California, Irvine, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 144 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 86-02, Section: B.
- 주기사항
- Advisor: Patterson, Joseph.
- 학위논문주기
- Thesis (Ph.D.)--University of California, Irvine, 2024.
- 초록/해제
- 요약Metal-organic frameworks (MOFs) present a diverse platform for designing high-performance materials with applications spanning drug delivery, catalysis, sensing, and separation. MOF polymorphism has been widely studied from the perspective of which synthetic factors, such as ligand-to-metal ratio, solvent, and temperature, can be used to control the final polymorph formation. However, limited studies on the nucleation mechanism of multi-polymorph MOFs have been performed. This dissertation aims to highlight the study and understanding of metal-organic framework polymorphs and how to observe and control polymorph formation. Advanced microscopy, scattering and spectroscopy techniques such as cryogenic transmission electron microscopy (cryoTEM), scanning electron microscopy (SEM), powder x-ray diffraction (PXRD), and electrospray ionization mass spectrometry (ESI-MS) are employed to conduct these studies. Here we study the formation of a model zeolitic imidazole framework-8 (ZIF-8) and the mechanism that drives the formation of the two most observed polymorphs, sodalite (SOD) and diamondoid (dia). To understand the mechanism and factors that affect polymorph formation, the prenucleation clusters were studied mainly through in-situ WAXS and ESI-MS, uncovering the role of prenucleation cluster size on the polymorph formation. In a follow up study, we investigate the effect of confinement through reaction vessel size on the nucleation and growth of ZIF-8. This study is of importance for studies involving analytical techniques where the experimental reaction volume varies from the bulk reaction. In addition, we study the encapsulation of bovine serum albumin (BSA) in ZIF-8 frameworks and the effect of supramolecular modification with cyclodextrin on the encapsulation efficiency. To further the studies with cyclodextrin, cyclodextrin-based MOFs are studied to understand their encapsulation efficiency and structure. In summary, this work provides insights into the field of MOF nucleation and growth through a lens of polymorph control and lays the foundation for the development of new MOFs.
- 일반주제명
- Chemistry
- 일반주제명
- Inorganic chemistry
- 일반주제명
- Materials science
- 기타저자
- University of California, Irvine Chemistry
- 기본자료저록
- Dissertations Abstracts International. 86-02B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■00520250211151950
■006m o d
■007cr#unu||||||||
■020 ▼a9798383596005
■035 ▼a(MiAaPQ)AAI31328306
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a540
■1001 ▼aTalosig, A. Rain.
■24510▼aUnderstanding the Nucleation and Growth of ZIF-8 Polymorphs
■260 ▼a[Sl]▼bUniversity of California, Irvine▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a144 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 86-02, Section: B.
■500 ▼aAdvisor: Patterson, Joseph.
■5021 ▼aThesis (Ph.D.)--University of California, Irvine, 2024.
■520 ▼aMetal-organic frameworks (MOFs) present a diverse platform for designing high-performance materials with applications spanning drug delivery, catalysis, sensing, and separation. MOF polymorphism has been widely studied from the perspective of which synthetic factors, such as ligand-to-metal ratio, solvent, and temperature, can be used to control the final polymorph formation. However, limited studies on the nucleation mechanism of multi-polymorph MOFs have been performed. This dissertation aims to highlight the study and understanding of metal-organic framework polymorphs and how to observe and control polymorph formation. Advanced microscopy, scattering and spectroscopy techniques such as cryogenic transmission electron microscopy (cryoTEM), scanning electron microscopy (SEM), powder x-ray diffraction (PXRD), and electrospray ionization mass spectrometry (ESI-MS) are employed to conduct these studies. Here we study the formation of a model zeolitic imidazole framework-8 (ZIF-8) and the mechanism that drives the formation of the two most observed polymorphs, sodalite (SOD) and diamondoid (dia). To understand the mechanism and factors that affect polymorph formation, the prenucleation clusters were studied mainly through in-situ WAXS and ESI-MS, uncovering the role of prenucleation cluster size on the polymorph formation. In a follow up study, we investigate the effect of confinement through reaction vessel size on the nucleation and growth of ZIF-8. This study is of importance for studies involving analytical techniques where the experimental reaction volume varies from the bulk reaction. In addition, we study the encapsulation of bovine serum albumin (BSA) in ZIF-8 frameworks and the effect of supramolecular modification with cyclodextrin on the encapsulation efficiency. To further the studies with cyclodextrin, cyclodextrin-based MOFs are studied to understand their encapsulation efficiency and structure. In summary, this work provides insights into the field of MOF nucleation and growth through a lens of polymorph control and lays the foundation for the development of new MOFs.
■590 ▼aSchool code: 0030.
■650 4▼aChemistry
■650 4▼aInorganic chemistry
■650 4▼aMaterials science
■653 ▼aMetal organic frameworks
■653 ▼aNucleation mechanism
■653 ▼aScanning electron microscopy
■653 ▼aCryogenic transmission electron microscopy
■653 ▼aPowder x-ray diffraction
■690 ▼a0485
■690 ▼a0488
■690 ▼a0794
■71020▼aUniversity of California, Irvine▼bChemistry.
■7730 ▼tDissertations Abstracts International▼g86-02B.
■790 ▼a0030
■791 ▼aPh.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17162249▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
