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Fabrication and Packaging of Three-Dimensional Parylene C Neural Interfaces
Fabrication and Packaging of Three-Dimensional Parylene C Neural Interfaces
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20250211152734
- ISBN
- 9798383693490
- DDC
- 610
- 서명/저자
- Fabrication and Packaging of Three-Dimensional Parylene C Neural Interfaces
- 발행사항
- [Sl] : University of Southern California, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 257 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 86-02, Section: B.
- 주기사항
- Advisor: Meng, Ellis.
- 학위논문주기
- Thesis (Ph.D.)--University of Southern California, 2024.
- 초록/해제
- 요약The field of microelectromechanical systems (MEMS) has enabled the creation of microscale systems which have impacted a number of fields. In the field of neural interfaces, MEMS has enabled significant miniaturization of electrodes from the millimeter scale to the micron scale. This reduction in size allows neural interfaces to be less invasive, reducing the body's immune response and improving patient outcomes, and to interface with the tissue on a smaller size scale, increasing spatial resolution of neural recording or stimulation. MEMS devices, however, are built in a planar configuration, limiting their ability to interface with complex 3D geometry in the body. To overcome this challenge, Parylene-based planar MEMS devices can be permanently transformed into 3D shapes via post-processing, enabling countless more applications of such devices to interface with non-planar anatomy.This work first discusses the post-processing of Parylene-based MEMS devices to produce 3D structures via the modulation of film stress and thermoforming, described in chapter 2. Chapters 3 and 4 apply that process to develop two novel devices to interface with complex anatomy in the body. The first (chapter 3) is an endovascular electrode array for neural recording from within the blood vessels, aimed at minimally invasive seizure monitoring. The second (chapter 4) is a peripheral nerve cuff electrode for chronic stimulation of small diameter branched nerves, designed to produce more targeted neuromodulation for a variety of different applications.
- 일반주제명
- Biomedical engineering
- 일반주제명
- Packaging
- 일반주제명
- Bioengineering
- 키워드
- 3D geometry
- 키워드
- 3D shapes
- 키워드
- MEMS devices
- 키워드
- Fabrication
- 기타저자
- University of Southern California Biomedical Engineering
- 기본자료저록
- Dissertations Abstracts International. 86-02B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■00520250211152734
■006m o d
■007cr#unu||||||||
■020 ▼a9798383693490
■035 ▼a(MiAaPQ)AAI31491155
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a610
■1001 ▼aThielen, Brianna.
■24510▼aFabrication and Packaging of Three-Dimensional Parylene C Neural Interfaces
■260 ▼a[Sl]▼bUniversity of Southern California▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a257 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 86-02, Section: B.
■500 ▼aAdvisor: Meng, Ellis.
■5021 ▼aThesis (Ph.D.)--University of Southern California, 2024.
■520 ▼aThe field of microelectromechanical systems (MEMS) has enabled the creation of microscale systems which have impacted a number of fields. In the field of neural interfaces, MEMS has enabled significant miniaturization of electrodes from the millimeter scale to the micron scale. This reduction in size allows neural interfaces to be less invasive, reducing the body's immune response and improving patient outcomes, and to interface with the tissue on a smaller size scale, increasing spatial resolution of neural recording or stimulation. MEMS devices, however, are built in a planar configuration, limiting their ability to interface with complex 3D geometry in the body. To overcome this challenge, Parylene-based planar MEMS devices can be permanently transformed into 3D shapes via post-processing, enabling countless more applications of such devices to interface with non-planar anatomy.This work first discusses the post-processing of Parylene-based MEMS devices to produce 3D structures via the modulation of film stress and thermoforming, described in chapter 2. Chapters 3 and 4 apply that process to develop two novel devices to interface with complex anatomy in the body. The first (chapter 3) is an endovascular electrode array for neural recording from within the blood vessels, aimed at minimally invasive seizure monitoring. The second (chapter 4) is a peripheral nerve cuff electrode for chronic stimulation of small diameter branched nerves, designed to produce more targeted neuromodulation for a variety of different applications.
■590 ▼aSchool code: 0208.
■650 4▼aBiomedical engineering
■650 4▼aPackaging
■650 4▼aBioengineering
■653 ▼aMicroelectromechanical systems
■653 ▼a3D geometry
■653 ▼a3D shapes
■653 ▼aMEMS devices
■653 ▼aFabrication
■690 ▼a0541
■690 ▼a0202
■690 ▼a0549
■71020▼aUniversity of Southern California▼bBiomedical Engineering.
■7730 ▼tDissertations Abstracts International▼g86-02B.
■790 ▼a0208
■791 ▼aPh.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17163634▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
