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Permanent Pacemaker Implantation After Tricuspid Valve Repair Surgery
Permanent Pacemaker Implantation After Tricuspid Valve Repair Surgery
Permanent Pacemaker Implantation After Tricuspid Valve Repair Surgery

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자료유형  
 학위논문 서양
최종처리일시  
20250211151108
ISBN  
9798382321240
DDC  
610
저자명  
Morrison, Alyssa Rae.
서명/저자  
Permanent Pacemaker Implantation After Tricuspid Valve Repair Surgery
발행사항  
[Sl] : Yale University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
46 p
주기사항  
Source: Dissertations Abstracts International, Volume: 85-11, Section: B.
주기사항  
Advisor: Chaudhry, Sarwat;Geirrson, Arnar.
학위논문주기  
Thesis (M.D.)--Yale University, 2024.
초록/해제  
요약Recent studies suggest that permanent pacemaker implantation after tricuspid valve repair may be more common than previously thought. Our primary aim was to assess the rates of early (within 30 days of surgery) and late (more than 30 days after surgery) permanent pacemaker implantation (PPI) after tricuspid valve repair (TVr) surgery. Our secondary aims included exploring risk factors for PPI after TVr and assessing outcomes.We performed a retrospective analysis of 231 isolated and concomitant tricuspid valve repairs for primary and secondary tricuspid valve regurgitation at a single quaternary academic center performed from 2014-2022.Early pacemaker implantation was performed in 10.0% of patients (n=23) at median 6 (interquartile range [IQR], 5-7) days after surgery, with a range of 2-14 days. In assessing differences between patients with early pacemaker implantation and those without, there were no significant differences between the groups regarding baseline demographic characteristics, comorbidities, or operative characteristics. The indications for the pacemakers were atrioventricular node block in 69.6% and sinoatrial node dysfunction in 30.4%. Median follow-up was 2.8 (IQR, 1.2-4.8) years. Late pacemaker implantation, more than 30 days after surgery, occurred in 15 patients (7.2%), median 1.2 (IQR, 0.6-4.6) years after tricuspid valve repair. Although these analyses were under-powered, we found that the patient and surgical factors we evaluated, including history of atrial fibrillation and MAZE procedure, were not significant predictors of PPI. There was no significant difference in the long-term survival based on early pacemaker implantation status (unadjusted hazard ratio 0.54, 95% CI 0.22-1.37, P=0.305) or late pacemaker implantation (unadjusted hazard ratio 0.79, 95% CI 0.19-2.18, P=0.695).The rate of permanent pacemaker implantation following tricuspid valve repair within 30 days postoperatively in our cohort was 10.0%, suggesting pacemaker implantation is not an uncommon occurrence in the perioperative period, and typically occurs within the first 10 days. Atrioventricular block accounts for the majority of early pacemakers (69.6%), followed by sinoatrial node dysfunction (30.4%).
일반주제명  
Medicine
일반주제명  
Surgery
일반주제명  
Physiology
키워드  
Pacemaker
키워드  
Tricuspid valve repair
키워드  
Permanent pacemaker implantation
키워드  
Atrioventricular node
기타저자  
Yale University Yale School of Medicine
기본자료저록  
Dissertations Abstracts International. 85-11B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aMorrison,  Alyssa  Rae.
■24510▼aPermanent  Pacemaker  Implantation  After  Tricuspid  Valve  Repair  Surgery
■260    ▼a[Sl]▼bYale  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a46  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-11,  Section:  B.
■500    ▼aAdvisor:  Chaudhry,  Sarwat;Geirrson,  Arnar.
■5021  ▼aThesis  (M.D.)--Yale  University,  2024.
■520    ▼aRecent  studies  suggest  that  permanent  pacemaker  implantation  after  tricuspid  valve  repair  may  be  more  common  than  previously  thought.  Our  primary  aim  was  to  assess  the  rates  of  early  (within  30  days  of  surgery)  and  late  (more  than  30  days  after  surgery)  permanent  pacemaker  implantation  (PPI)  after  tricuspid  valve  repair  (TVr)  surgery.  Our  secondary  aims  included  exploring  risk  factors  for  PPI  after  TVr  and  assessing  outcomes.We  performed  a  retrospective  analysis  of  231  isolated  and  concomitant  tricuspid  valve  repairs  for  primary  and  secondary  tricuspid  valve  regurgitation  at  a  single  quaternary  academic  center  performed  from  2014-2022.Early  pacemaker  implantation  was  performed  in  10.0%  of  patients  (n=23)  at  median  6  (interquartile  range  [IQR],  5-7)  days  after  surgery,  with  a  range  of  2-14  days.  In  assessing  differences  between  patients  with  early  pacemaker  implantation  and  those  without,  there  were  no  significant  differences  between  the  groups  regarding  baseline  demographic  characteristics,  comorbidities,  or  operative  characteristics.  The  indications  for  the  pacemakers  were  atrioventricular  node  block  in  69.6%  and  sinoatrial  node  dysfunction  in  30.4%.  Median  follow-up  was  2.8  (IQR,  1.2-4.8)  years.  Late  pacemaker  implantation,  more  than  30  days  after  surgery,  occurred  in  15  patients  (7.2%),  median  1.2  (IQR,  0.6-4.6)  years  after  tricuspid  valve  repair.  Although  these  analyses  were  under-powered,  we  found  that  the  patient  and  surgical  factors  we  evaluated,  including  history  of  atrial  fibrillation  and  MAZE  procedure,  were  not  significant  predictors  of  PPI.  There  was  no  significant  difference  in  the  long-term  survival  based  on  early  pacemaker  implantation  status  (unadjusted  hazard  ratio  0.54,  95%  CI  0.22-1.37,  P=0.305)  or  late  pacemaker  implantation  (unadjusted  hazard  ratio  0.79,  95%  CI  0.19-2.18,  P=0.695).The  rate  of  permanent  pacemaker  implantation  following  tricuspid  valve  repair  within  30  days  postoperatively  in  our  cohort  was  10.0%,  suggesting  pacemaker  implantation  is  not  an  uncommon  occurrence  in  the  perioperative  period,  and  typically  occurs  within  the  first  10  days.  Atrioventricular  block  accounts  for  the  majority  of  early  pacemakers  (69.6%),  followed  by  sinoatrial  node  dysfunction  (30.4%).
■590    ▼aSchool  code:  0265.
■650  4▼aMedicine
■650  4▼aSurgery
■650  4▼aPhysiology
■653    ▼aPacemaker
■653    ▼aTricuspid  valve  repair
■653    ▼aPermanent  pacemaker  implantation
■653    ▼aAtrioventricular  node
■690    ▼a0564
■690    ▼a0576
■690    ▼a0719
■71020▼aYale  University▼bYale  School  of  Medicine.
■7730  ▼tDissertations  Abstracts  International▼g85-11B.
■790    ▼a0265
■791    ▼aM.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17160729▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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