본문

서브메뉴

Learning Brain Dynamics With Neural Operators
Learning Brain Dynamics With Neural Operators
Learning Brain Dynamics With Neural Operators

Detailed Information

자료유형  
 학위논문 서양
최종처리일시  
20250211150914
ISBN  
9798383565872
DDC  
616
저자명  
de Oliveira Fonseca, Antonio Henrique.
서명/저자  
Learning Brain Dynamics With Neural Operators
발행사항  
[Sl] : Yale University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
162 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-02, Section: B.
주기사항  
Advisor: van Dijk, David;Cardin, Jessica.
학위논문주기  
Thesis (Ph.D.)--Yale University, 2024.
초록/해제  
요약Understanding the intricate workings of the brain remains one of science's grand challenges. At its core, the brain operates as a dynamic system, with neural oscillations and coordinated activity patterns enabling integrated cognition. However, modeling these complex dynamics computationally has proven difficult. Traditional models often rely on restrictive assumptions about brain activity properties, limiting their utility. This thesis introduces innovative machine learning frameworks, utilizing neural operator techniques specifically designed for neural data, to model brain dynamics more effectively.Neural operators function as mappings between infinite-dimensional spaces, offering a flexible, data-driven approach to capture the complex spatiotemporal relationships in neural dynamics. This work presents four novel machine learning frameworks. The Neural Integro-Differential Equations (NIDEs) integrate instantaneous and temporal components, providing enhanced accuracy for complex systems like the brain. Attentional Neural Integral Equations ((A)NIEs) harness self-attention mechanisms to learn and compute unknown integral operators from data. The Continuous Spatiotemporal Transformers (CSTs) leverage a new Transformer architecture to model continuous systems directly from data, overcoming the limitations of traditional methods. Brain Language Models (BrainLMs) utilize extensive fMRI dataset pretraining and finetuning, offering unmatched versatility in modeling brain dynamics.Analyses of synthetic and real-world data validate these models' superior performance. NIDEs reveal the local and non-local effects of substances like ketamine on fMRI dynamics. (A)NIEs and CSTs demonstrate superior predictive capabilities in modeling fMRI and wide-field recordings, outperforming existing methods for learning dynamics. BrainLM efficiently identifies intrinsic functional networks and, through insilico perturbation analysis, showcases its ability to differentiate subject states using accumulated knowledge.Collectively, these advancements not only broaden the horizons of modeling diverse neural modalities and data types but also break free from the constraints of previous methodologies. The frameworks extend their utility to various dynamic modeling domains, enhancing flexibility. This thesis highlights the immense potential of AI in offering comprehensive insights and unraveling the organizational principles of complex systems, marking a significant stride in technology-driven neuroscience research.
일반주제명  
Neurosciences
일반주제명  
Computer science
일반주제명  
Physiology
일반주제명  
Medical imaging
키워드  
Computational neuroscience
키워드  
Data-driven algorithms
키워드  
Machine learning
키워드  
Neural dynamics
키워드  
Neural operators
키워드  
Spatiotemporal modeling
기타저자  
Yale University Neuroscience
기본자료저록  
Dissertations Abstracts International. 86-02B.
전자적 위치 및 접속  
로그인 후 원문을 볼 수 있습니다.

MARC

 008250123s2024        us                              c    eng  d
■001000017160126
■00520250211150914
■006m          o    d                
■007cr#unu||||||||
■020    ▼a9798383565872
■035    ▼a(MiAaPQ)AAI30812400
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a616
■1001  ▼ade  Oliveira  Fonseca,  Antonio  Henrique.
■24510▼aLearning  Brain  Dynamics  With  Neural  Operators
■260    ▼a[Sl]▼bYale  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a162  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-02,  Section:  B.
■500    ▼aAdvisor:  van  Dijk,  David;Cardin,  Jessica.
■5021  ▼aThesis  (Ph.D.)--Yale  University,  2024.
■520    ▼aUnderstanding  the  intricate  workings  of  the  brain  remains  one  of  science's  grand  challenges.  At  its  core,  the  brain  operates  as  a  dynamic  system,  with  neural  oscillations  and  coordinated  activity  patterns  enabling  integrated  cognition.  However,  modeling  these  complex  dynamics  computationally  has  proven  difficult.  Traditional  models  often  rely  on  restrictive  assumptions  about  brain  activity  properties,  limiting  their  utility.  This  thesis  introduces  innovative  machine  learning  frameworks,  utilizing  neural  operator  techniques  specifically  designed  for  neural  data,  to  model  brain  dynamics  more  effectively.Neural  operators  function  as  mappings  between  infinite-dimensional  spaces,  offering  a  flexible,  data-driven  approach  to  capture  the  complex  spatiotemporal  relationships  in  neural  dynamics.  This  work  presents  four  novel  machine  learning  frameworks.  The  Neural  Integro-Differential  Equations  (NIDEs)  integrate  instantaneous  and  temporal  components,  providing  enhanced  accuracy  for  complex  systems  like  the  brain.  Attentional  Neural  Integral  Equations  ((A)NIEs)  harness  self-attention  mechanisms  to  learn  and  compute  unknown  integral  operators  from  data.  The  Continuous  Spatiotemporal  Transformers  (CSTs)  leverage  a  new  Transformer  architecture  to  model  continuous  systems  directly  from  data,  overcoming  the  limitations  of  traditional  methods.  Brain  Language  Models  (BrainLMs)  utilize  extensive  fMRI  dataset  pretraining  and  finetuning,  offering  unmatched  versatility  in  modeling  brain  dynamics.Analyses  of  synthetic  and  real-world  data  validate  these  models'  superior  performance.  NIDEs  reveal  the  local  and  non-local  effects  of  substances  like  ketamine  on  fMRI  dynamics.  (A)NIEs  and  CSTs  demonstrate  superior  predictive  capabilities  in  modeling  fMRI  and  wide-field  recordings,  outperforming  existing  methods  for  learning  dynamics.  BrainLM  efficiently  identifies  intrinsic  functional  networks  and,  through  insilico  perturbation  analysis,  showcases  its  ability  to  differentiate  subject  states  using  accumulated  knowledge.Collectively,  these  advancements  not  only  broaden  the  horizons  of  modeling  diverse  neural  modalities  and  data  types  but  also  break  free  from  the  constraints  of  previous  methodologies.  The  frameworks  extend  their  utility  to  various  dynamic  modeling  domains,  enhancing  flexibility.  This  thesis  highlights  the  immense  potential  of  AI  in  offering  comprehensive  insights  and  unraveling  the  organizational  principles  of  complex  systems,  marking  a  significant  stride  in  technology-driven  neuroscience  research.
■590    ▼aSchool  code:  0265.
■650  4▼aNeurosciences
■650  4▼aComputer  science
■650  4▼aPhysiology
■650  4▼aMedical  imaging
■653    ▼aComputational  neuroscience
■653    ▼aData-driven  algorithms
■653    ▼aMachine  learning
■653    ▼aNeural  dynamics
■653    ▼aNeural  operators
■653    ▼aSpatiotemporal  modeling
■690    ▼a0317
■690    ▼a0984
■690    ▼a0719
■690    ▼a0574
■71020▼aYale  University▼bNeuroscience.
■7730  ▼tDissertations  Abstracts  International▼g86-02B.
■790    ▼a0265
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17160126▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

Preview

Export

ChatGPT Discussion

AI Recommended Related Books


    New Books MORE
    Statistics for the past 3 years. Go to brief

    Подробнее информация.

    • Бронирование
    • не существует
    • моя папка
    • Первый запрос зрения
    • Non-Book Loan Application
    • Nighttime Book Loan Application
    материал
    Reg No. Количество платежных Местоположение статус Ленд информации
    TF13054 전자도서 대출가능 My Folder 부재도서신고 비도서대출신청 야간 도서대출신청

    * Бронирование доступны в заимствований книги. Чтобы сделать предварительный заказ, пожалуйста, нажмите кнопку бронирование

    Books borrowed together with this book

    Related Popular Books

    Available after logging in.