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Epidemiological Surveys in India and Marine Natural Product Drug Discovery for Malaria
Epidemiological Surveys in India and Marine Natural Product Drug Discovery for Malaria
Epidemiological Surveys in India and Marine Natural Product Drug Discovery for Malaria

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자료유형  
 학위논문 서양
최종처리일시  
20250211151947
ISBN  
9798383222119
DDC  
540
저자명  
Karschney, Laura Jacquelyn.
서명/저자  
Epidemiological Surveys in India and Marine Natural Product Drug Discovery for Malaria
발행사항  
[Sl] : University of Washington, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
89 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-01, Section: B.
주기사항  
Advisor: Rathod, Pradipsinh K.;Theberge, Ashleigh B.
학위논문주기  
Thesis (Ph.D.)--University of Washington, 2024.
초록/해제  
요약This dissertation discusses malaria epidemiology, pathogenesis, and drug discovery projects. Chapter 1 presents background on malaria, its lifecycle, the history of antimalarials and development of resistance, and the Malaria Evolution in South Asia International Center of Excellence for Malaria Research. Chapter 2 details demographic and clinical profiles of Plasmodium falciparum and Plasmodium vivax patients at a tertiary hospital in the southwestern state of Goa, India. Chapter 3 presents a dynamic cohort study conducted in seven remote villages of the northeastern state of Assam, India and the impact of longitudinal malaria diagnosis and treatment on the remote tribal population. Chapter 4 details the bioactivity of a secondary metabolite of a marine symbiotic bacterium against sexual and asexual Plasmodium falciparum. The work presented in this dissertation demonstrates how aspects of different scientific disciplines may be utilized in combination to better understand the biology and community impacts of a major infectious disease and to respond to the urgent need for new antimicrobials.
일반주제명  
Chemistry
일반주제명  
Biology
일반주제명  
Epidemiology
일반주제명  
Microbiology
키워드  
Assam
키워드  
Goa
키워드  
MESA-ICEMR
키워드  
Pathogenesis
키워드  
Plasmodium falciparum
키워드  
Tartrolon E
기타저자  
University of Washington Chemistry
기본자료저록  
Dissertations Abstracts International. 86-01B.
전자적 위치 및 접속  
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MARC

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■00520250211151947
■006m          o    d                
■007cr#unu||||||||
■020    ▼a9798383222119
■035    ▼a(MiAaPQ)AAI31327919
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a540
■1001  ▼aKarschney,  Laura  Jacquelyn.
■24510▼aEpidemiological  Surveys  in  India  and  Marine  Natural  Product  Drug  Discovery  for  Malaria
■260    ▼a[Sl]▼bUniversity  of  Washington▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a89  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-01,  Section:  B.
■500    ▼aAdvisor:  Rathod,  Pradipsinh  K.;Theberge,  Ashleigh  B.
■5021  ▼aThesis  (Ph.D.)--University  of  Washington,  2024.
■520    ▼aThis  dissertation  discusses  malaria  epidemiology,  pathogenesis,  and  drug  discovery  projects.  Chapter  1  presents  background  on  malaria,  its  lifecycle,  the  history  of  antimalarials  and  development  of  resistance,  and  the  Malaria  Evolution  in  South  Asia  International  Center  of  Excellence  for  Malaria  Research.  Chapter  2  details  demographic  and  clinical  profiles  of  Plasmodium  falciparum  and  Plasmodium  vivax  patients  at  a  tertiary  hospital  in  the  southwestern  state  of  Goa,  India.  Chapter  3  presents  a  dynamic  cohort  study  conducted  in  seven  remote  villages  of  the  northeastern  state  of  Assam,  India  and  the  impact  of  longitudinal  malaria  diagnosis  and  treatment  on  the  remote  tribal  population.  Chapter  4  details  the  bioactivity  of  a  secondary  metabolite  of  a  marine  symbiotic  bacterium  against  sexual  and  asexual  Plasmodium  falciparum.  The  work  presented  in  this  dissertation  demonstrates  how  aspects  of  different  scientific  disciplines  may  be  utilized  in  combination  to  better  understand  the  biology  and  community  impacts  of  a  major  infectious  disease  and  to  respond  to  the  urgent  need  for  new  antimicrobials.
■590    ▼aSchool  code:  0250.
■650  4▼aChemistry
■650  4▼aBiology
■650  4▼aEpidemiology
■650  4▼aMicrobiology
■653    ▼aAssam
■653    ▼aGoa
■653    ▼aMESA-ICEMR
■653    ▼aPathogenesis
■653    ▼aPlasmodium  falciparum
■653    ▼aTartrolon  E
■690    ▼a0485
■690    ▼a0306
■690    ▼a0766
■690    ▼a0410
■71020▼aUniversity  of  Washington▼bChemistry.
■7730  ▼tDissertations  Abstracts  International▼g86-01B.
■790    ▼a0250
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17162224▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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