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Predicting Depression in Black Women: A Machine Learning Epigenetic Approach
Predicting Depression in Black Women: A Machine Learning Epigenetic Approach
Predicting Depression in Black Women: A Machine Learning Epigenetic Approach

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자료유형  
 학위논문 서양
최종처리일시  
20250211152802
ISBN  
9798383701737
DDC  
610.73
저자명  
Taylor, Brittany N.
서명/저자  
Predicting Depression in Black Women: A Machine Learning Epigenetic Approach
발행사항  
[Sl] : Columbia University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
213 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-02, Section: A.
주기사항  
Advisor: Masterson Creber, Ruth.
학위논문주기  
Thesis (Ph.D.)--Columbia University, 2024.
초록/해제  
요약Depression is one of the most widespread and disabling mental health disorders affecting adults worldwide, and Black women bear a disproportionate burden of this disorder. With its varied symptom presentation, depression can be difficult to diagnose. In addition, Black women may be less likely to report symptoms due to cultural stigma. The purpose of this dissertation is to examine the associations between social determinants of health and depressive symptoms using DNA methylation data and machine learning to predict depressive symptoms in Black women. Chapter 2 contains two comprehensive literature reviews: a scoping review of machine learning methods used to analyze omics data to classify depressed cases and healthy controls and a concept analysis of depression in Black mothers. Chapter 3 examines associations between social determinants of health, depressive symptoms, and DNA methylation. Chapter 3A focuses on socioeconomic deprivation; Chapter 3B focuses on perceived income inadequacy; and Chapter 3C identifies differential methylation associated with depressive symptoms. Chapter 4 utilizes supervised machine learning algorithms to predict depressive symptoms and perform feature selection. These chapters show the harmful effects that perceived discrimination can have on the mental health of Black women. Additionally, the results indicate that DNA methylation is associated with depressive symptoms, an area which requires further research.
일반주제명  
Nursing
일반주제명  
Bioinformatics
일반주제명  
Mental health
일반주제명  
Womens studies
일반주제명  
Clinical psychology
키워드  
Black women
키워드  
Depression
키워드  
Epigenetics
키워드  
Machine learning
키워드  
Social determinants of health
기타저자  
Columbia University Nursing
기본자료저록  
Dissertations Abstracts International. 86-02A.
전자적 위치 및 접속  
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■1001  ▼aTaylor,  Brittany  N.
■24510▼aPredicting  Depression  in  Black  Women:  A  Machine  Learning  Epigenetic  Approach
■260    ▼a[Sl]▼bColumbia  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a213  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-02,  Section:  A.
■500    ▼aAdvisor:  Masterson  Creber,  Ruth.
■5021  ▼aThesis  (Ph.D.)--Columbia  University,  2024.
■520    ▼aDepression  is  one  of  the  most  widespread  and  disabling  mental  health  disorders  affecting  adults  worldwide,  and  Black  women  bear  a  disproportionate  burden  of  this  disorder.  With  its  varied  symptom  presentation,  depression  can  be  difficult  to  diagnose.  In  addition,  Black  women  may  be  less  likely  to  report  symptoms  due  to  cultural  stigma.    The  purpose  of  this  dissertation  is  to  examine  the  associations  between  social  determinants  of  health  and  depressive  symptoms  using  DNA  methylation  data  and  machine  learning  to  predict  depressive  symptoms  in  Black  women.  Chapter  2  contains  two  comprehensive  literature  reviews:  a  scoping  review  of  machine  learning  methods  used  to  analyze  omics  data  to  classify  depressed  cases  and  healthy  controls  and  a  concept  analysis  of  depression  in  Black  mothers.  Chapter  3  examines  associations  between  social  determinants  of  health,  depressive  symptoms,  and  DNA  methylation.  Chapter  3A  focuses  on  socioeconomic  deprivation;  Chapter  3B  focuses  on  perceived  income  inadequacy;  and  Chapter  3C  identifies  differential  methylation  associated  with  depressive  symptoms.  Chapter  4  utilizes  supervised  machine  learning  algorithms  to  predict  depressive  symptoms  and  perform  feature  selection.  These  chapters  show  the  harmful  effects  that  perceived  discrimination  can  have  on  the  mental  health  of  Black  women.  Additionally,  the  results  indicate  that  DNA  methylation  is  associated  with  depressive  symptoms,  an  area  which  requires  further  research.
■590    ▼aSchool  code:  0054.
■650  4▼aNursing
■650  4▼aBioinformatics
■650  4▼aMental  health
■650  4▼aWomens  studies
■650  4▼aClinical  psychology
■653    ▼aBlack  women
■653    ▼aDepression
■653    ▼aEpigenetics
■653    ▼aMachine  learning
■653    ▼aSocial  determinants  of  health
■690    ▼a0569
■690    ▼a0715
■690    ▼a0453
■690    ▼a0622
■690    ▼a0347
■71020▼aColumbia  University▼bNursing.
■7730  ▼tDissertations  Abstracts  International▼g86-02A.
■790    ▼a0054
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17163864▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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