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Statistical Methods for the Study of Effect Modification and Spatial Causal Inference: Theory and Applications
Statistical Methods for the Study of Effect Modification and Spatial Causal Inference: The...
Statistical Methods for the Study of Effect Modification and Spatial Causal Inference: Theory and Applications

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20250211151448
ISBN  
9798382776811
DDC  
310
저자명  
Cohn, Eric R.
서명/저자  
Statistical Methods for the Study of Effect Modification and Spatial Causal Inference: Theory and Applications
발행사항  
[Sl] : Harvard University, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
198 p
주기사항  
Source: Dissertations Abstracts International, Volume: 85-12, Section: B.
주기사항  
Advisor: Zubizarreta, Jose R.
학위논문주기  
Thesis (Ph.D.)--Harvard University, 2024.
초록/해제  
요약More and more, scientists and policymakers are interested in using quantitative methods to answer complex causal questions across diverse contexts. This thesis proposes and implements statistical methods for inferring causation beyond simple average effects, for example, how causal effects vary across populations or by individual characteristics. It also proposes and develops theory for estimators of causal effects in the kinds of complex spatial settings encountered in practice, where data may not obey classical statistical assumptions like independence.Chapter 1 introduces profile matching, a multivariate matching method for randomized experiments and observational studies that finds the largest possible unweighted samples across multiple treatment groups that are balanced relative to a covariate profile. By selecting the profile appropriately, profile matching can be a flexible tool for investigators to generalize or transport effect estimates across populations while retaining the simple structure of unweighted data.Chapter 2 presents a framework for the study of heterogeneous treatment effects in difference-in-differences designs in a study of the effects of firearm injuries on survivors and their family members. This framework encompasses a novel set of identification assumptions and sensitivity analysis for difference-in-differences with staggered treatment adoption. The method for covariate adjustment combines risk set matching with profile matching, which respects the time alignment of variable measurements while also controlling bias due to observed covariate imbalances in subgroups discovered from the data. Inference on main effects and treatment effect heterogeneity entails randomization-based techniques.Chapter 3 presents and analyzes semiparametric estimators of causal effects in settings where the data exhibit spatial dependence, where the dependence assumptions are considerably weaker than those in the existing causal inference literature. We prove that the treatment effect estimator is asymptotically normal and that the proposed block bootstrap sampling variance estimator is consistent. The proofs of these results rely on novel extensions of central limit and empirical process theory for dependent data.
일반주제명  
Statistics
일반주제명  
Public policy
일반주제명  
Public health
일반주제명  
Biostatistics
키워드  
Causal inferences
키워드  
Effect modification
키워드  
Health policy
키워드  
Observational studies
키워드  
Spatial statistics
기타저자  
Harvard University Biostatistics
기본자료저록  
Dissertations Abstracts International. 85-12B.
전자적 위치 및 접속  
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MARC

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■035    ▼a(MiAaPQ)AAI31296589
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a310
■1001  ▼aCohn,  Eric  R.▼0(orcid)0000-0001-7264-0566
■24510▼aStatistical  Methods  for  the  Study  of  Effect  Modification  and  Spatial  Causal  Inference:  Theory  and  Applications
■260    ▼a[Sl]▼bHarvard  University▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a198  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  85-12,  Section:  B.
■500    ▼aAdvisor:  Zubizarreta,  Jose  R.
■5021  ▼aThesis  (Ph.D.)--Harvard  University,  2024.
■520    ▼aMore  and  more,  scientists  and  policymakers  are  interested  in  using  quantitative  methods  to  answer  complex  causal  questions  across  diverse  contexts.  This  thesis  proposes  and  implements  statistical  methods  for  inferring  causation  beyond  simple  average  effects,  for  example,  how  causal  effects  vary  across  populations  or  by  individual  characteristics.  It  also  proposes  and  develops  theory  for  estimators  of  causal  effects  in  the  kinds  of  complex  spatial  settings  encountered  in  practice,  where  data  may  not  obey  classical  statistical  assumptions  like  independence.Chapter  1  introduces  profile  matching,  a  multivariate  matching  method  for  randomized  experiments  and  observational  studies  that  finds  the  largest  possible  unweighted  samples  across  multiple  treatment  groups  that  are  balanced  relative  to  a  covariate  profile.  By  selecting  the  profile  appropriately,  profile  matching  can  be  a  flexible  tool  for  investigators  to  generalize  or  transport  effect  estimates  across  populations  while  retaining  the  simple  structure  of  unweighted  data.Chapter  2  presents  a  framework  for  the  study  of  heterogeneous  treatment  effects  in  difference-in-differences  designs  in  a  study  of  the  effects  of  firearm  injuries  on  survivors  and  their  family  members.  This  framework  encompasses  a  novel  set  of  identification  assumptions  and  sensitivity  analysis  for  difference-in-differences  with  staggered  treatment  adoption.  The  method  for  covariate  adjustment  combines  risk  set  matching  with  profile  matching,  which  respects  the  time  alignment  of  variable  measurements  while  also  controlling  bias  due  to  observed  covariate  imbalances  in  subgroups  discovered  from  the  data.  Inference  on  main  effects  and  treatment  effect  heterogeneity  entails  randomization-based  techniques.Chapter  3  presents  and  analyzes  semiparametric  estimators  of  causal  effects  in  settings  where  the  data  exhibit  spatial  dependence,  where  the  dependence  assumptions  are  considerably  weaker  than  those  in  the  existing  causal  inference  literature.  We  prove  that  the  treatment  effect  estimator  is  asymptotically  normal  and  that  the  proposed  block  bootstrap  sampling  variance  estimator  is  consistent.  The  proofs  of  these  results  rely  on  novel  extensions  of  central  limit  and  empirical  process  theory  for  dependent  data.
■590    ▼aSchool  code:  0084.
■650  4▼aStatistics
■650  4▼aPublic  policy
■650  4▼aPublic  health
■650  4▼aBiostatistics
■653    ▼aCausal  inferences
■653    ▼aEffect  modification
■653    ▼aHealth  policy
■653    ▼aObservational  studies
■653    ▼aSpatial  statistics
■690    ▼a0463
■690    ▼a0630
■690    ▼a0573
■690    ▼a0501
■690    ▼a0308
■71020▼aHarvard  University▼bBiostatistics.
■7730  ▼tDissertations  Abstracts  International▼g85-12B.
■790    ▼a0084
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17161809▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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