본문

서브메뉴

Meditations on Molecular Motors
Meditations on Molecular Motors
Meditations on Molecular Motors

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20250211151313
ISBN  
9798384472742
DDC  
501
저자명  
Bollhagen, Andrew.
서명/저자  
Meditations on Molecular Motors
발행사항  
[Sl] : University of California, San Diego, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
235 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-04, Section: B.
주기사항  
Advisor: Bechtel, William.
학위논문주기  
Thesis (Ph.D.)--University of California, San Diego, 2024.
초록/해제  
요약My dissertation represents the first sustained philosophical treatment of the science of molecular motor proteins-proteins that transform the chemical energy stored in ATP into mechanical motion. The analysis proceeds from a broadly mechanistic philosophical perspective, albeit one that has witnessed two recent developments. First, philosophers both within and in the orbit of mechanist philosophy of science have recently turned philosophical attention to how scientists characterize phenomena, as opposed to explain them, the latter being New Mechanism's traditional focus. The first section, Characterization (Chapters 1 & 2), contributes to this still nascent philosophical discussion. I draw case studies from the history of cell biological research on motor proteins to analyze key experimental practices by which scientists succeeded in characterizing (as opposed to explaining) the activity of molecule motor proteins both quantitatively (Chapter 1) and qualitatively (Chapter 2). Second, the perspective on biological mechanisms that I adopt is a "revisionist" one initially formulated by my supervisor, William Bechtel, and his former graduate student Jason Winning that construes biological mechanisms as sets of constraints on the flow of free energy. Each chapter of the second section, Explanation (Chapters 3, 4, &5) extends this philosophical view in connection with analyses of the explanatory practices of molecular motors researchers.
일반주제명  
Philosophy of science
일반주제명  
Cellular biology
일반주제명  
Biochemistry
키워드  
Mechanistic explanation
키워드  
Molecular motors
키워드  
Molecular motor proteins
기타저자  
University of California, San Diego Philosophy
기본자료저록  
Dissertations Abstracts International. 86-04B.
전자적 위치 및 접속  
로그인 후 원문을 볼 수 있습니다.

MARC

 008250123s2024        us                              c    eng  d
■001000017161124
■00520250211151313
■006m          o    d                
■007cr#unu||||||||
■020    ▼a9798384472742
■035    ▼a(MiAaPQ)AAI31237561
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a501
■1001  ▼aBollhagen,  Andrew.
■24510▼aMeditations  on  Molecular  Motors
■260    ▼a[Sl]▼bUniversity  of  California,  San  Diego▼c2024
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2024
■300    ▼a235  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-04,  Section:  B.
■500    ▼aAdvisor:  Bechtel,  William.
■5021  ▼aThesis  (Ph.D.)--University  of  California,  San  Diego,  2024.
■520    ▼aMy  dissertation  represents  the  first  sustained  philosophical  treatment  of  the  science  of  molecular  motor  proteins-proteins  that  transform  the  chemical  energy  stored  in  ATP  into  mechanical  motion.  The  analysis  proceeds  from  a  broadly  mechanistic  philosophical  perspective,  albeit  one  that  has  witnessed  two  recent  developments.  First,  philosophers  both  within  and  in  the  orbit  of  mechanist  philosophy  of  science  have  recently  turned  philosophical  attention  to  how  scientists  characterize  phenomena,  as  opposed  to  explain  them,  the  latter  being  New  Mechanism's  traditional  focus.  The  first  section,  Characterization  (Chapters  1  &  2),  contributes  to  this  still  nascent  philosophical  discussion.  I  draw  case  studies  from  the  history  of  cell  biological  research  on  motor  proteins  to  analyze  key  experimental  practices  by  which  scientists  succeeded  in  characterizing  (as  opposed  to  explaining)  the  activity  of  molecule  motor  proteins  both  quantitatively  (Chapter  1)  and  qualitatively  (Chapter  2).  Second,  the  perspective  on  biological  mechanisms  that  I  adopt  is  a  "revisionist"  one  initially  formulated  by  my  supervisor,  William  Bechtel,  and  his  former  graduate  student  Jason  Winning  that  construes  biological  mechanisms  as  sets  of  constraints  on  the  flow  of  free  energy.  Each  chapter  of  the  second  section,  Explanation  (Chapters  3,  4,  &5)  extends  this  philosophical  view  in  connection  with  analyses  of  the  explanatory  practices  of  molecular  motors  researchers.
■590    ▼aSchool  code:  0033.
■650  4▼aPhilosophy  of  science
■650  4▼aCellular  biology
■650  4▼aBiochemistry
■653    ▼aMechanistic  explanation
■653    ▼aMolecular  motors
■653    ▼aMolecular  motor  proteins
■690    ▼a0402
■690    ▼a0379
■690    ▼a0487
■71020▼aUniversity  of  California,  San  Diego▼bPhilosophy.
■7730  ▼tDissertations  Abstracts  International▼g86-04B.
■790    ▼a0033
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17161124▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

미리보기

내보내기

chatGPT토론

Ai 추천 관련 도서


    신착도서 더보기
    최근 3년간 통계입니다.

    소장정보

    • 예약
    • 소재불명신고
    • 나의폴더
    • 우선정리요청
    • 비도서대출신청
    • 야간 도서대출신청
    소장자료
    등록번호 청구기호 소장처 대출가능여부 대출정보
    TF14043 전자도서 대출가능 마이폴더 부재도서신고 비도서대출신청 야간 도서대출신청

    * 대출중인 자료에 한하여 예약이 가능합니다. 예약을 원하시면 예약버튼을 클릭하십시오.

    해당 도서를 다른 이용자가 함께 대출한 도서

    관련 인기도서

    로그인 후 이용 가능합니다.