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A Dimensional Approach to Perinatal Mania and Psychosis
A Dimensional Approach to Perinatal Mania and Psychosis
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202104809
- ISBN
- 9798291503232
- DDC
- 157
- 서명/저자
- A Dimensional Approach to Perinatal Mania and Psychosis
- 발행사항
- [Sl] : University of Minnesota, 2025
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2025
- 형태사항
- 156 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 87-02, Section: B.
- 주기사항
- Advisor: Gunnar, Megan R.;Krueger, Robert F.
- 학위논문주기
- Thesis (Ph.D.)--University of Minnesota, 2025.
- 초록/해제
- 요약Clear and compelling evidence links childbirth with heightened risk for mania and psychosis. Research is primarily limited to perinatal women with categorical diagnoses, despite consensus that symptoms of mania and psychosis are fully continuous in the general population. As with perinatal depression and anxiety, subthreshold symptoms of perinatal mania and psychosis are likely to be empirically and clinically meaningful. Further, these symptoms are likely to be missed with current screening methods. This prospective, longitudinal study examined the prevalence, course, and correlates of dimensionally-assessed symptoms of mania and psychosis in a general sample of 168 individuals giving birth for the first time. Across four timepoints from late pregnancy through 2 months postpartum, symptoms were measured with validated questionnaires. At 2 months postpartum, mother-infant interaction and infant development were characterized with standardized observational protocols. Dried blood spot cytokine (IL-6, IL-10, TNF-α) and hair cortisol levels were determined at three timepoints. As hypothesized, mania and psychosis showed dimensionality and significant longitudinal change. Symptoms of mania symptoms peaked in the immediate postpartum, along with symptoms of depression and anxiety, while symptoms of psychosis declined from late pregnancy to 2 months postpartum. In support of the second hypothesis, higher scores on a mania and psychosis composite were uniquely associated with less optimal maternal sensitivity, after accounting for depression and anxiety composite scores and other key covariates. The mania and psychosis symptom composite also were associated with lower infant cognitive development, though not independent of the depression and anxiety symptom composite. Average levels of perinatal cortisol and cytokines were generally unrelated to symptom dimensions, though in secondary, longitudinal analyses, higher symptoms of mania were associated with higher levels of IL-6, with this finding persisting after accounting for covariates, including depressive symptoms. Findings suggest that subclinical symptoms of mania and psychosis are an important, yet currently underdetected, feature of perinatal mental health in need of further investigation.
- 일반주제명
- Clinical psychology
- 일반주제명
- Developmental psychology
- 일반주제명
- Psychology
- 키워드
- Mania
- 키워드
- Postpartum
- 키워드
- Psychosis
- 기타저자
- University of Minnesota Developmental Psychology
- 기본자료저록
- Dissertations Abstracts International. 87-02B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■00520260202104809
■006m o d
■007cr#unu||||||||
■020 ▼a9798291503232
■035 ▼a(MiAaPQ)AAI32166708
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a157
■1001 ▼aHowland, Mariann A.
■24512▼aA Dimensional Approach to Perinatal Mania and Psychosis
■260 ▼a[Sl]▼bUniversity of Minnesota▼c2025
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a156 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 87-02, Section: B.
■500 ▼aAdvisor: Gunnar, Megan R.;Krueger, Robert F.
■5021 ▼aThesis (Ph.D.)--University of Minnesota, 2025.
■520 ▼aClear and compelling evidence links childbirth with heightened risk for mania and psychosis. Research is primarily limited to perinatal women with categorical diagnoses, despite consensus that symptoms of mania and psychosis are fully continuous in the general population. As with perinatal depression and anxiety, subthreshold symptoms of perinatal mania and psychosis are likely to be empirically and clinically meaningful. Further, these symptoms are likely to be missed with current screening methods. This prospective, longitudinal study examined the prevalence, course, and correlates of dimensionally-assessed symptoms of mania and psychosis in a general sample of 168 individuals giving birth for the first time. Across four timepoints from late pregnancy through 2 months postpartum, symptoms were measured with validated questionnaires. At 2 months postpartum, mother-infant interaction and infant development were characterized with standardized observational protocols. Dried blood spot cytokine (IL-6, IL-10, TNF-α) and hair cortisol levels were determined at three timepoints. As hypothesized, mania and psychosis showed dimensionality and significant longitudinal change. Symptoms of mania symptoms peaked in the immediate postpartum, along with symptoms of depression and anxiety, while symptoms of psychosis declined from late pregnancy to 2 months postpartum. In support of the second hypothesis, higher scores on a mania and psychosis composite were uniquely associated with less optimal maternal sensitivity, after accounting for depression and anxiety composite scores and other key covariates. The mania and psychosis symptom composite also were associated with lower infant cognitive development, though not independent of the depression and anxiety symptom composite. Average levels of perinatal cortisol and cytokines were generally unrelated to symptom dimensions, though in secondary, longitudinal analyses, higher symptoms of mania were associated with higher levels of IL-6, with this finding persisting after accounting for covariates, including depressive symptoms. Findings suggest that subclinical symptoms of mania and psychosis are an important, yet currently underdetected, feature of perinatal mental health in need of further investigation.
■590 ▼aSchool code: 0130.
■650 4▼aClinical psychology
■650 4▼aDevelopmental psychology
■650 4▼aPsychology
■653 ▼aInfant development
■653 ▼aMania
■653 ▼aMaternal sensitivity
■653 ▼aPerinatal depression
■653 ▼aPostpartum
■653 ▼aPsychosis
■690 ▼a0622
■690 ▼a0620
■690 ▼a0621
■71020▼aUniversity of Minnesota▼bDevelopmental Psychology.
■7730 ▼tDissertations Abstracts International▼g87-02B.
■790 ▼a0130
■791 ▼aPh.D.
■792 ▼a2025
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17358917▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
