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In the Shadow of Postpartum Depression: An Investigation of the Heterogeneity of Perinatal Psychopathology During the COVID-19 Pandemic
In the Shadow of Postpartum Depression: An Investigation of the Heterogeneity of Perinatal...
In the Shadow of Postpartum Depression: An Investigation of the Heterogeneity of Perinatal Psychopathology During the COVID-19 Pandemic

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20260202105157
ISBN  
9798297615434
DDC  
157
저자명  
Alhomaizi, Alaa.
서명/저자  
In the Shadow of Postpartum Depression: An Investigation of the Heterogeneity of Perinatal Psychopathology During the COVID-19 Pandemic
발행사항  
[Sl] : Columbia University, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
507 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-04, Section: B.
주기사항  
Advisor: Verdeli, Helen.
학위논문주기  
Thesis (Ph.D.)--Columbia University, 2025.
초록/해제  
요약Background: Beginning in March 2020, pregnant, laboring, and postpartum women were dealing with the challenges inherent to the perinatal period against the backdrop of a global pandemic. By the beginning of 2022, as the risk of the Omicron wave loomed and the pandemic had closed on its second year, there was a cohort of women who had their entire pregnancy and some, if not almost all, of their postpartum period during the pandemic. When the crisis changed from acute to chronic, it became imperative to investigate how the prolonged nature of the pandemic affected perinatal women, and importantly, understand the nature and manifestation of perinatal symptomatology experienced by these women. Prior to the pandemic, there was growing scientific evidence of the heterogeneous nature of maternal psychopathology during the perinatal period. Therefore, it was important to investigate whether the same pattern of heterogeneity will underlie the perinatal mental health outcomes during the COVID-19 pandemic, and to see whether this heterogeneity can be organized into phenotypic patterns of symptom expression. The overall aim of our study was to investigate the heterogeneity of perinatal psychopathology during the COVID-19 pandemic by identifying and describing symptom profiles, and to identify the correlates of symptom profile membership. Additionally, a secondary aim of our study was an in-depth investigation of the role and manifestation of irritability, an understudied and overlooked area in perinatal research, as it related to perinatal psychopathology during the COVID-19 pandemic.Method: This study utilized cross-sectional data (N = 630) from the Pregnancy, Postpartum, and Parenting During a Pandemic Study (P-4) online survey, which included scales measuring demographic information, psychosocial risk factors, maternal emotional well-being and functioning, and COVID-19-related life events. First, we used confirmatory factor analysis and exploratory factor analysis to determine the factor structures of the Center for Epidemiologic Studies Depression Scale (CES-D) and Perinatal Anxiety Screening Scale (PASS) to create factor-based subscales. We then used these factor-based subscales as indicators for a latent class analysis (LCA) to identify symptom profiles (i.e., classes) of perinatal psychopathology during the COVID-19 pandemic. Afterwards, we investigated correlates that were associated with class membership, including demographic variables, psychosocial predictors, onset of symptoms, COVID-19-related life events, and COVID-19 changes to the perinatal period. We utilized analysis of variance (ANOVA) with the continuous variables and multinomial logistic regression with the categorical variables. Then, we characterized irritability in our sample and established its clinical relevance. We examined irritability's relationship with depression, anxiety, maternal functioning, and suicidality via Spearman correlations and linear regressions. We also examined psychosocial predictors of irritability via stepwise regression. Finally, we used ANOVA to examine the differences in the levels of irritability symptoms, including state and trait irritability, as well as irritability's impact on various domains (e.g., family relationships), across the symptom profiles.Results: Four depression factors from the CES-D and five anxiety factors from the PASS were used as factor-based indicators in the LCA. We determined that a five-class solution best fit the data. We identified three quantitative classes that primarily differed from each other in symptom severity, and we labeled them Non-Clinical (n = 268), Average (n = 167), and Severe Psychopathology (n = 60). We also identified two qualitative classes, which did not differ from each other in overall symptom severity, but instead, exhibited a set of unique elevations that suggested distinct phenotypic symptom expressions. We labeled the two classes Interpersonally Sensitive (n = 104) and Postpartum Obsessive-Compulsive Symptoms (OCS) (n = 31). Generally, the correlates of class membership revealed that greater risk factors, and lower protective factors, were associated with greater symptom severity. However, there were some key exceptions to this pattern, as evidenced by the qualitative classes with similar severity levels, such as: 1) the Interpersonally Sensitive class reported the second highest rate of suicidal ideation; and 2) participants who endorsed a history of psychiatric symptoms or baby blues had the highest likelihood of belonging to the Postpartum OCS class, compared to the Non-Clinical class. As for irritability, it was associated with higher clinical depression and anxiety, as well as lower maternal functioning and higher suicidal ideation in the overall sample. Finally, we found that classes with greater symptom severity reported higher rates of irritability, and those with similar symptom severity levels (i.e., Interpersonally Sensitive and Postpartum OCS) reported comparable irritability levels. However, while overall irritability did not differ between the two qualitative classes, there was a trend towards state irritability being more relevant for the Postpartum OCS class and trait irritability being more relevant for the Interpersonally Sensitive class.Conclusions: Our results revealed significant heterogeneity in phenotypic symptom expression among perinatal women during the COVID-19 pandemic. All classes reported symptoms of depression and anxiety, underscoring that comorbid symptoms are the norm, not the exception, for this population. Critically, since two classes (i.e., Interpersonally Sensitive and Postpartum OCS) had similar levels of global severity, but exhibited distinct overall symptom profiles, it underscored the importance of using key symptom elevations, not total scores, to guide identification and treatment of perinatal psychopathology. Finally, irritability was a marker of distress and related to global severity, and as such, should be incorporated within the detection and treatment of perinatal psychopathology. Future research should examine whether the diverse symptom profiles identified in this study can be replicated outside the context of a global stressor, such as the COVID-19 pandemic.
일반주제명  
Clinical psychology
일반주제명  
Psychology
키워드  
COVID-19 pandemic
키워드  
Perinatal anxiety
키워드  
Perinatal depression
키워드  
Perinatal psychopathology
기타저자  
Columbia University TC: Clinical Psychology
기본자료저록  
Dissertations Abstracts International. 87-04B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aAlhomaizi,  Alaa.
■24510▼aIn  the  Shadow  of  Postpartum  Depression:  An  Investigation  of  the  Heterogeneity  of  Perinatal  Psychopathology  During  the  COVID-19  Pandemic
■260    ▼a[Sl]▼bColumbia  University▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a507  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-04,  Section:  B.
■500    ▼aAdvisor:  Verdeli,  Helen.
■5021  ▼aThesis  (Ph.D.)--Columbia  University,  2025.
■520    ▼aBackground:  Beginning  in  March  2020,  pregnant,  laboring,  and  postpartum  women  were  dealing  with  the  challenges  inherent  to  the  perinatal  period  against  the  backdrop  of  a  global  pandemic.  By  the  beginning  of  2022,  as  the  risk  of  the  Omicron  wave  loomed  and  the  pandemic  had  closed  on  its  second  year,  there  was  a  cohort  of  women  who  had  their  entire  pregnancy  and  some,  if  not  almost  all,  of  their  postpartum  period  during  the  pandemic.  When  the  crisis  changed  from  acute  to  chronic,  it  became  imperative  to  investigate  how  the  prolonged  nature  of  the  pandemic  affected  perinatal  women,  and  importantly,  understand  the  nature  and  manifestation  of  perinatal  symptomatology  experienced  by  these  women.  Prior  to  the  pandemic,  there  was  growing  scientific  evidence  of  the  heterogeneous  nature  of  maternal  psychopathology  during  the  perinatal  period.  Therefore,  it  was  important  to  investigate  whether  the  same  pattern  of  heterogeneity  will  underlie  the  perinatal  mental  health  outcomes  during  the  COVID-19  pandemic,  and  to  see  whether  this  heterogeneity  can  be  organized  into  phenotypic  patterns  of  symptom  expression.  The  overall  aim  of  our  study  was  to  investigate  the  heterogeneity  of  perinatal  psychopathology  during  the  COVID-19  pandemic  by  identifying  and  describing  symptom  profiles,  and  to  identify  the  correlates  of  symptom  profile  membership.  Additionally,  a  secondary  aim  of  our  study  was  an  in-depth  investigation  of  the  role  and  manifestation  of  irritability,  an  understudied  and  overlooked  area  in  perinatal  research,  as  it  related  to  perinatal  psychopathology  during  the  COVID-19  pandemic.Method:  This  study  utilized  cross-sectional  data  (N  =  630)  from  the  Pregnancy,  Postpartum,  and  Parenting  During  a  Pandemic  Study  (P-4)  online  survey,  which  included  scales  measuring  demographic  information,  psychosocial  risk  factors,  maternal  emotional  well-being  and  functioning,  and  COVID-19-related  life  events.  First,  we  used  confirmatory  factor  analysis  and  exploratory  factor  analysis  to  determine  the  factor  structures  of  the  Center  for  Epidemiologic  Studies  Depression  Scale  (CES-D)  and  Perinatal  Anxiety  Screening  Scale  (PASS)  to  create  factor-based  subscales.  We  then  used  these  factor-based  subscales  as  indicators  for  a  latent  class  analysis  (LCA)  to  identify  symptom  profiles  (i.e.,  classes)  of  perinatal  psychopathology  during  the  COVID-19  pandemic.  Afterwards,  we  investigated  correlates  that  were  associated  with  class  membership,  including  demographic  variables,  psychosocial  predictors,  onset  of  symptoms,  COVID-19-related  life  events,  and  COVID-19  changes  to  the  perinatal  period.  We  utilized  analysis  of  variance  (ANOVA)  with  the  continuous  variables  and  multinomial  logistic  regression  with  the  categorical  variables.  Then,  we  characterized  irritability  in  our  sample  and  established  its  clinical  relevance.  We  examined  irritability's  relationship  with  depression,  anxiety,  maternal  functioning,  and  suicidality  via  Spearman  correlations  and  linear  regressions.  We  also  examined  psychosocial  predictors  of  irritability  via  stepwise  regression.  Finally,  we  used  ANOVA  to  examine  the  differences  in  the  levels  of  irritability  symptoms,  including  state  and  trait  irritability,  as  well  as  irritability's  impact  on  various  domains  (e.g.,  family  relationships),  across  the  symptom  profiles.Results:  Four  depression  factors  from  the  CES-D  and  five  anxiety  factors  from  the  PASS  were  used  as  factor-based  indicators  in  the  LCA.  We  determined  that  a  five-class  solution  best  fit  the  data.  We  identified  three  quantitative  classes  that  primarily  differed  from  each  other  in  symptom  severity,  and  we  labeled  them  Non-Clinical  (n  =  268),  Average  (n  =  167),  and  Severe Psychopathology  (n  =  60).  We  also  identified  two  qualitative  classes,  which  did  not  differ  from  each  other  in  overall  symptom  severity,  but  instead,  exhibited  a  set  of  unique  elevations  that  suggested  distinct  phenotypic  symptom  expressions.  We  labeled  the  two  classes  Interpersonally  Sensitive  (n  =  104)  and  Postpartum  Obsessive-Compulsive  Symptoms  (OCS)  (n  =  31).  Generally,  the  correlates  of  class  membership  revealed  that  greater  risk  factors,  and  lower  protective  factors,  were  associated  with  greater  symptom  severity.  However,  there  were  some  key  exceptions  to  this  pattern,  as  evidenced  by  the  qualitative  classes  with  similar  severity  levels,  such  as:  1)  the  Interpersonally  Sensitive  class  reported  the  second  highest  rate  of  suicidal  ideation;  and  2)  participants  who  endorsed  a  history  of  psychiatric  symptoms  or  baby  blues  had  the  highest  likelihood  of  belonging  to  the  Postpartum  OCS  class,  compared  to  the  Non-Clinical  class.  As  for  irritability,  it  was  associated  with  higher  clinical  depression  and  anxiety,  as  well  as  lower  maternal  functioning  and  higher  suicidal  ideation  in  the  overall  sample.  Finally,  we  found  that  classes  with  greater  symptom  severity  reported  higher  rates  of  irritability,  and  those  with  similar  symptom  severity  levels  (i.e.,  Interpersonally  Sensitive  and  Postpartum  OCS)  reported  comparable  irritability  levels.  However,  while  overall  irritability  did  not  differ  between  the  two  qualitative  classes,  there  was  a  trend  towards  state  irritability  being  more  relevant  for  the  Postpartum  OCS  class  and  trait  irritability  being  more  relevant  for  the  Interpersonally  Sensitive  class.Conclusions:  Our  results  revealed  significant  heterogeneity  in  phenotypic  symptom  expression  among  perinatal  women  during  the  COVID-19  pandemic.  All  classes  reported  symptoms  of  depression  and  anxiety,  underscoring  that  comorbid  symptoms  are  the  norm,  not  the  exception,  for  this  population.  Critically,  since  two  classes  (i.e.,  Interpersonally  Sensitive  and  Postpartum  OCS)  had  similar  levels  of  global  severity,  but  exhibited  distinct  overall  symptom  profiles,  it underscored  the  importance  of  using  key  symptom  elevations,  not  total  scores,  to  guide  identification  and  treatment  of  perinatal  psychopathology.  Finally,  irritability  was  a  marker  of  distress  and  related  to  global  severity,  and  as  such,  should  be  incorporated  within  the  detection  and  treatment  of  perinatal  psychopathology.  Future  research  should  examine  whether  the  diverse  symptom  profiles  identified  in  this  study  can  be  replicated  outside  the  context  of  a  global  stressor,  such  as  the  COVID-19  pandemic.
■590    ▼aSchool  code:  0054.
■650  4▼aClinical  psychology
■650  4▼aPsychology
■653    ▼aCOVID-19  pandemic
■653    ▼aPerinatal  anxiety
■653    ▼aPerinatal  depression
■653    ▼aPerinatal  psychopathology
■690    ▼a0622
■690    ▼a0621
■71020▼aColumbia  University▼bTC:  Clinical  Psychology.
■7730  ▼tDissertations  Abstracts  International▼g87-04B.
■790    ▼a0054
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359678▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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