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Genetic Covariance Between Populations and Chromosomal Contributions to Genetic Variance in Maize
Genetic Covariance Between Populations and Chromosomal Contributions to Genetic Variance in Maize
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202105157
- ISBN
- 9798297648999
- DDC
- 580
- 서명/저자
- Genetic Covariance Between Populations and Chromosomal Contributions to Genetic Variance in Maize
- 발행사항
- [Sl] : University of Minnesota, 2025
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2025
- 형태사항
- 109 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 87-04, Section: B.
- 주기사항
- Advisor: Bernardo, Rex.
- 학위논문주기
- Thesis (Ph.D.)--University of Minnesota, 2025.
- 초록/해제
- 요약Variance, a measure of dispersion of a variable around its mean, and covariance, a measure of the joint variation of two variables, have long been foundational concepts in quantitative genetics. Models and simulations often assume homogeneous genetic variances and covariances between populations and uniform distributions of quantitative trait loci across populations. However, these assumptions are frequently violated in practical breeding programs that involve structured populations with different pedigrees. In this work, I first developed and validated a framework for estimating the genetic covariance between populations via their molecular marker effects in a simulated dataset with known covariances, and in a maize (Zea mays L.) dataset from a commercial breeding program. The simulated populations confirmed the method's expected behavior, whereas the maize dataset showed trait- and population-specific covariance patterns. Next, I evaluated whether modeling heterogeneous genetic covariances among structured populations improves the accuracy of genomewide prediction compared to conventional homogeneous covariance models. Using both simulated and maize data, I found no consistent advantage of heterogeneous covariance models; simpler homogeneous covariance models generally provided equal or better predictive performance. A theoretical analysis indicated that benefits of heterogeneous models depend on a relationship between marker similarity and genetic covariance, but this relationship was not prevalent in the data. Finally, I evaluated whether the contribution of each chromosome to genetic variance is proportional to its length. The results showed that the genetic variance contributed by each chromosome was generally proportional to chromosome size. Exceptions to this pattern arose from the preponderance of either coupling linkages, which produced a higher-than-expected contribution, or repulsion linkages, which produced a lower-than-expected contribution. This result indicated that for quantitative traits in elite maize germplasm, genetic gains will mostly arise from finding favorable arrangements of alleles on chromosomes rather than finding chromosome copies that carry multiple major genes.
- 일반주제명
- Plant sciences
- 일반주제명
- Genetics
- 일반주제명
- Microbiology
- 일반주제명
- Biology
- 키워드
- Zea mays
- 기타저자
- University of Minnesota Applied Plant Sciences
- 기본자료저록
- Dissertations Abstracts International. 87-04B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■00520260202105157
■006m o d
■007cr#unu||||||||
■020 ▼a9798297648999
■035 ▼a(MiAaPQ)AAI32243439
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a580
■1001 ▼aRebollo Panuncio, Maria Ines.
■24510▼aGenetic Covariance Between Populations and Chromosomal Contributions to Genetic Variance in Maize
■260 ▼a[Sl]▼bUniversity of Minnesota▼c2025
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a109 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 87-04, Section: B.
■500 ▼aAdvisor: Bernardo, Rex.
■5021 ▼aThesis (Ph.D.)--University of Minnesota, 2025.
■520 ▼aVariance, a measure of dispersion of a variable around its mean, and covariance, a measure of the joint variation of two variables, have long been foundational concepts in quantitative genetics. Models and simulations often assume homogeneous genetic variances and covariances between populations and uniform distributions of quantitative trait loci across populations. However, these assumptions are frequently violated in practical breeding programs that involve structured populations with different pedigrees. In this work, I first developed and validated a framework for estimating the genetic covariance between populations via their molecular marker effects in a simulated dataset with known covariances, and in a maize (Zea mays L.) dataset from a commercial breeding program. The simulated populations confirmed the method's expected behavior, whereas the maize dataset showed trait- and population-specific covariance patterns. Next, I evaluated whether modeling heterogeneous genetic covariances among structured populations improves the accuracy of genomewide prediction compared to conventional homogeneous covariance models. Using both simulated and maize data, I found no consistent advantage of heterogeneous covariance models; simpler homogeneous covariance models generally provided equal or better predictive performance. A theoretical analysis indicated that benefits of heterogeneous models depend on a relationship between marker similarity and genetic covariance, but this relationship was not prevalent in the data. Finally, I evaluated whether the contribution of each chromosome to genetic variance is proportional to its length. The results showed that the genetic variance contributed by each chromosome was generally proportional to chromosome size. Exceptions to this pattern arose from the preponderance of either coupling linkages, which produced a higher-than-expected contribution, or repulsion linkages, which produced a lower-than-expected contribution. This result indicated that for quantitative traits in elite maize germplasm, genetic gains will mostly arise from finding favorable arrangements of alleles on chromosomes rather than finding chromosome copies that carry multiple major genes.
■590 ▼aSchool code: 0130.
■650 4▼aPlant sciences
■650 4▼aGenetics
■650 4▼aMicrobiology
■650 4▼aBiology
■653 ▼aGenomic prediction
■653 ▼aQuantitative genetics
■653 ▼aZea mays
■653 ▼aBreeding programs
■690 ▼a0479
■690 ▼a0369
■690 ▼a0410
■690 ▼a0306
■71020▼aUniversity of Minnesota▼bApplied Plant Sciences.
■7730 ▼tDissertations Abstracts International▼g87-04B.
■790 ▼a0130
■791 ▼aPh.D.
■792 ▼a2025
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359680▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


