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Key Components for Planning and Developing New Pharmaceutical Enterprises That Produce COVID-19 Vaccines in Nigeria for Local Uptake : 在尼日利亚规划和发展生产COVID-19疫苗的新制药企业的关键组成部分,以促进当地使用
Key Components for Planning and Developing New Pharmaceutical Enterprises That Produce COV...
Key Components for Planning and Developing New Pharmaceutical Enterprises That Produce COVID-19 Vaccines in Nigeria for Local Uptake : 在尼日利亚规划和发展生产COVID-19疫苗的新制药企业的关键组成部分,以促进当地使用

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자료유형  
 학위논문 서양
최종처리일시  
20260202105002
ISBN  
9798291503713
DDC  
615
저자명  
Aremu, Taiwo Opeyemi.
서명/저자  
Key Components for Planning and Developing New Pharmaceutical Enterprises That Produce COVID-19 Vaccines in Nigeria for Local Uptake : 在尼日利亚规划和发展生产COVID-19疫苗的新制药企业的关键组成部分,以促进当地使用
발행사항  
[Sl] : University of Minnesota, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
139 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-02, Section: A.
주기사항  
Advisor: Okoro, Olihe;Gaither, Caroline.
학위논문주기  
Thesis (Ph.D.)--University of Minnesota, 2025.
초록/해제  
요약The COVID-19 pandemic reignited global conversations around vaccine access, underscoring the urgent need for local manufacturing capacity in low- and middle-income countries. Despite its large population and growing pharmaceutical sector, Nigeria relied entirely on imported COVID-19 vaccines. This study investigates the critical components necessary to establish a vaccine manufacturing enterprise capable of meeting domestic demand in Nigeria. A mixed-methods design was employed, combining interviews with six senior stakeholders in the regulatory and pharmaceutical sectors and a survey of 335 adults in Lagos State. Qualitative data were thematically analyzed to explore institutional, regulatory, and workforce-related barriers. Quantitative analysis assessed demographic predictors of public willingness to accept a locally produced COVID-19 vaccine. Interview participants identified core challenges including inadequate technical workforce, poor infrastructure, limited political support, and regulatory delays. Survey results showed that 76 percent of respondents would accept a Nigerian-made COVID-19 vaccine, with significantly higher acceptance among older adults and Muslim participants. Factors such as gender, employment, and educational attainment were not statistically associated with vaccine acceptance. This study contributes to ongoing discourse on regional vaccine self-reliance by offering an integrated analysis of supply-side constraints and demand-side readiness in an urban Nigerian context. These findings provide context-specific insights to support strategic planning, capacity building, and trust-building measures needed for sustainable local vaccine production.
일반주제명  
Pharmaceutical sciences
일반주제명  
Pharmacology
일반주제명  
Sustainability
키워드  
Vaccine production
키워드  
Health systems
키워드  
Nigeria
키워드  
Pharmaceutical manufacturing
키워드  
Sustainable development goals
키워드  
Vaccine equity
키워드  
COVID-19 pandemic
기타저자  
University of Minnesota Social and Administrative Pharmacy
기본자료저록  
Dissertations Abstracts International. 87-02A.
전자적 위치 및 접속  
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■040    ▼aMiAaPQ▼cMiAaPQ
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■1001  ▼aAremu,  Taiwo  Opeyemi.
■24510▼aKey  Components  for  Planning  and  Developing  New  Pharmaceutical  Enterprises  That  Produce  COVID-19  Vaccines  in  Nigeria  for  Local  Uptake  ▼b在尼日利亚规划和发展生产COVID-19疫苗的新制药企业的关键组成部分,以促进当地使用
■260    ▼a[Sl]▼bUniversity  of  Minnesota▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a139  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-02,  Section:  A.
■500    ▼aAdvisor:  Okoro,  Olihe;Gaither,  Caroline.
■5021  ▼aThesis  (Ph.D.)--University  of  Minnesota,  2025.
■520    ▼aThe  COVID-19  pandemic  reignited  global  conversations  around  vaccine  access,  underscoring  the  urgent  need  for  local  manufacturing  capacity  in  low-  and  middle-income  countries.  Despite  its  large  population  and  growing  pharmaceutical  sector,  Nigeria  relied  entirely  on  imported  COVID-19  vaccines.  This  study  investigates  the  critical  components  necessary  to  establish  a  vaccine  manufacturing  enterprise  capable  of  meeting  domestic  demand  in  Nigeria.  A  mixed-methods  design  was  employed,  combining  interviews  with  six  senior  stakeholders  in  the  regulatory  and  pharmaceutical  sectors  and  a  survey  of  335  adults  in  Lagos  State.  Qualitative  data  were  thematically  analyzed  to  explore  institutional,  regulatory,  and  workforce-related  barriers.  Quantitative  analysis  assessed  demographic  predictors  of  public  willingness  to  accept  a  locally  produced  COVID-19  vaccine.  Interview  participants  identified  core  challenges  including  inadequate  technical  workforce,  poor  infrastructure,  limited  political  support,  and  regulatory  delays.  Survey  results  showed  that  76  percent  of  respondents  would  accept  a  Nigerian-made  COVID-19  vaccine,  with  significantly  higher  acceptance  among  older  adults  and  Muslim  participants.  Factors  such  as  gender,  employment,  and  educational  attainment  were  not  statistically  associated  with  vaccine  acceptance.  This  study  contributes  to  ongoing  discourse  on  regional  vaccine  self-reliance  by  offering  an  integrated  analysis  of  supply-side  constraints  and  demand-side  readiness  in  an  urban  Nigerian  context.  These  findings  provide  context-specific  insights  to  support  strategic  planning,  capacity  building,  and  trust-building  measures  needed  for  sustainable  local  vaccine  production.
■590    ▼aSchool  code:  0130.
■650  4▼aPharmaceutical  sciences
■650  4▼aPharmacology
■650  4▼aSustainability
■653    ▼aVaccine  production
■653    ▼aHealth  systems
■653    ▼aNigeria
■653    ▼aPharmaceutical  manufacturing
■653    ▼aSustainable  development  goals
■653    ▼aVaccine  equity
■653    ▼aCOVID-19  pandemic
■690    ▼a0572
■690    ▼a0640
■690    ▼a0419
■71020▼aUniversity  of  Minnesota▼bSocial  and  Administrative  Pharmacy.
■7730  ▼tDissertations  Abstracts  International▼g87-02A.
■790    ▼a0130
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17359287▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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