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Moving Beyond Research Settings to Strengthen HIV Services: Determinants of Intervention Sustainability and Community-Generated Implementation Strategies
Moving Beyond Research Settings to Strengthen HIV Services: Determinants of Intervention S...
Moving Beyond Research Settings to Strengthen HIV Services: Determinants of Intervention Sustainability and Community-Generated Implementation Strategies

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자료유형  
 학위논문 서양
최종처리일시  
20260202104655
ISBN  
9798288833175
DDC  
614
저자명  
Shaw, Sarah A.
서명/저자  
Moving Beyond Research Settings to Strengthen HIV Services: Determinants of Intervention Sustainability and Community-Generated Implementation Strategies
발행사항  
[Sl] : University of Washington, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
158 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-01, Section: B.
주기사항  
Advisor: Wagner, Anjuli.
학위논문주기  
Thesis (Ph.D.)--University of Washington, 2025.
초록/해제  
요약The sustainment of evidence-based interventions (EBIs) that have implementer, beneficiary, and decision-maker buy-in is critical for maximizing long-term population health impacts. However, fewer than half of public health interventions are integrated into routine practice following a successful research trial, limiting their reach to communities who would benefit most-particularly communities who have been historically and continue to be under-resourced and marginalized. This persistent research-to-practice gap not only reduces anticipated public health impacts but also presents substantial ethical concerns. Planning for sustainability early in the research process, not just after implementation, and building equitable partnerships with communities through community-based participatory research (CBPR) approaches to ensure research is aligned with and driven by community priorities are essential for facilitating long-term implementation of EBIs. The limited and delayed translation of EBIs into routine practice is particularly salient for HIV programming, where despite global advances, significant inequities persist and effective interventions often remain confined to research settings.This dissertation applied a combination of participatory methods, strategy mapping, mixed-effects regression models, and a configurational comparative method (coincidence analysis) to examined sustainability from three complementary perspectives, drawing from two projects focused on improving HIV outcomes in the United States and Kenya. The primary objectives were to: (1) identify and characterize strategies to facilitate integrated HIV services and social determinants of health programming at three community-based organizations (CBOs) in King County, Washington; (2) assess implementation outcomes (acceptability, appropriateness, feasibility, fidelity, and sustainability) of the Adolescent Transition Package (ATP) that supports youth living with HIV (YLH) across 20 health facilities in Kenya one year after the effectiveness trial, examining associations between early implementation outcomes, fidelity, and intervention sustainability; and (3) identify combinations of multi-level determinants associated with high ATP sustainability in health facilities in Kenya one year post trial.Results from the first aim suggest that sustainable implementation of integrated services within CBOs may require systems-level approaches to strengthen organizational infrastructure and respond to community priorities. This community-academic partnership highlighted that implementation science frameworks may be unnecessary for strategy and determinant identification with CBOs, and instead, may be valuable for translating highly tailored strategies into potentially generalizable takeaways in similar contexts. Additionally, we observed patterns suggesting that examining feasibility and effectiveness of strategy types addressing unique combinations of determinants may strengthen barrier-strategy mapping.In the second aim, we observed high levels of acceptability, appropriateness, and feasibility of the ATP among healthcare workers (HCWs). These qualities likely contributed to the high perceived sustainability of the ATP, with each implementation outcome showing distinct and independent effects on sustainability. These results also suggest that after a research trial, intervention and control sites may require different implementation strategies to facilitate continued implementation. Intervention appropriateness emerged as particularly influential for sustainability for both intervention and control sites, while feasibility was more critical for control sites and acceptability more relevant for intervention sites.Lastly, the coincidence analysis conducted for the third aim highlighted fidelity as a necessary component of high ATP sustainability one year after the research trial, although it was not sufficient on its own. Instead, high ATP sustainability was a result of a combination of facility level factors (high adolescent client load, high awareness of the ATP across the health facility, and patterns in staff tenure) and fidelity. Two distinct pathways for achieving high sustainability were identified, emphasizing the need for scale-up and sustainability plans to reflect that there are likely multiple approaches that can lead to successful long-term implementation of EBIs.This research provides pragmatic, empirically grounded insights for policy development regarding EBI sustainability, health system supports for integrating social determinants of health into HIV services, and advancing our understanding and application of implementation science frameworks across contexts. Facilitating the translation of research findings into sustainable programming in routine practice settings will require embracing the dynamic complexity of implementation contexts and planning for sustainability throughout the entire research process. This work contributes meaningfully to bridging the know-do gap, ultimately working to ensure that effective interventions reach the communities that need them most.
일반주제명  
Public health
일반주제명  
Health sciences
일반주제명  
Translation studies
일반주제명  
Sustainability
키워드  
Evidence-based interventions
키워드  
Community-based participatory research
키워드  
Healthcare workers
키워드  
Adolescent Transition Package
기타저자  
University of Washington Global Health
기본자료저록  
Dissertations Abstracts International. 87-01B.
전자적 위치 및 접속  
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MARC

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■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-01,  Section:  B.
■500    ▼aAdvisor:  Wagner,  Anjuli.
■5021  ▼aThesis  (Ph.D.)--University  of  Washington,  2025.
■520    ▼aThe  sustainment  of  evidence-based  interventions  (EBIs)  that  have  implementer,  beneficiary,  and  decision-maker  buy-in  is  critical  for  maximizing  long-term  population  health  impacts.  However,  fewer  than  half  of  public  health  interventions  are  integrated  into  routine  practice  following  a  successful  research  trial,  limiting  their  reach  to  communities  who  would  benefit  most-particularly  communities  who  have  been  historically  and  continue  to  be  under-resourced  and  marginalized.  This  persistent  research-to-practice  gap  not  only  reduces  anticipated  public  health  impacts  but  also  presents  substantial  ethical  concerns.  Planning  for  sustainability  early  in  the  research  process,  not  just  after  implementation,  and  building  equitable  partnerships  with  communities  through  community-based  participatory  research  (CBPR)  approaches  to  ensure  research  is  aligned  with  and  driven  by  community  priorities  are  essential  for  facilitating  long-term  implementation  of  EBIs.  The  limited  and  delayed  translation  of  EBIs  into  routine  practice  is  particularly  salient  for  HIV  programming,  where  despite  global  advances,  significant  inequities  persist  and  effective  interventions  often  remain  confined  to  research  settings.This  dissertation  applied  a  combination  of  participatory  methods,  strategy  mapping,  mixed-effects  regression  models,  and  a  configurational  comparative  method  (coincidence  analysis)  to  examined  sustainability  from  three  complementary  perspectives,  drawing  from  two  projects  focused  on  improving  HIV  outcomes  in  the  United  States  and  Kenya.  The  primary  objectives  were  to:  (1)  identify  and  characterize  strategies  to  facilitate  integrated  HIV  services  and  social  determinants  of  health  programming  at  three  community-based  organizations  (CBOs)  in  King  County,  Washington;  (2)  assess  implementation  outcomes  (acceptability,  appropriateness,  feasibility,  fidelity,  and  sustainability)  of  the  Adolescent  Transition  Package  (ATP)  that  supports  youth  living  with  HIV  (YLH)  across  20  health  facilities  in  Kenya  one  year  after  the  effectiveness  trial,  examining  associations  between  early  implementation  outcomes,  fidelity,  and  intervention  sustainability;  and  (3)  identify  combinations  of  multi-level  determinants  associated  with  high  ATP  sustainability  in  health  facilities  in  Kenya  one  year  post  trial.Results  from  the  first  aim  suggest  that  sustainable  implementation  of  integrated  services  within  CBOs  may  require  systems-level  approaches  to  strengthen  organizational  infrastructure  and  respond  to  community  priorities.  This  community-academic  partnership  highlighted  that  implementation  science  frameworks  may  be  unnecessary  for  strategy  and  determinant  identification  with  CBOs,  and  instead,  may  be  valuable  for  translating  highly  tailored  strategies  into  potentially  generalizable  takeaways  in  similar  contexts.  Additionally,  we  observed  patterns  suggesting  that  examining  feasibility  and  effectiveness  of  strategy  types  addressing  unique  combinations  of  determinants  may  strengthen  barrier-strategy  mapping.In  the  second  aim,  we  observed  high  levels  of  acceptability,  appropriateness,  and  feasibility  of  the  ATP  among  healthcare  workers  (HCWs).  These  qualities  likely  contributed  to  the  high  perceived  sustainability  of  the  ATP,  with  each  implementation  outcome  showing  distinct  and  independent  effects  on  sustainability.  These  results  also  suggest  that  after  a  research  trial,  intervention  and  control  sites  may  require  different  implementation  strategies  to  facilitate  continued  implementation.  Intervention  appropriateness  emerged  as  particularly  influential  for  sustainability  for  both  intervention  and  control  sites,  while  feasibility  was  more  critical  for  control  sites  and  acceptability  more  relevant  for  intervention  sites.Lastly,  the  coincidence  analysis  conducted  for  the  third  aim  highlighted  fidelity  as  a  necessary  component  of  high  ATP  sustainability  one  year  after  the  research  trial,  although  it  was  not  sufficient  on  its  own.  Instead,  high  ATP  sustainability  was  a  result  of  a  combination  of  facility  level  factors  (high  adolescent  client  load,  high  awareness  of  the  ATP  across  the  health  facility,  and  patterns  in  staff  tenure)  and  fidelity.  Two  distinct  pathways  for  achieving  high  sustainability  were  identified,  emphasizing  the  need  for  scale-up  and  sustainability  plans  to  reflect  that  there  are  likely  multiple  approaches  that  can  lead  to  successful  long-term  implementation  of  EBIs.This  research  provides  pragmatic,  empirically  grounded  insights  for  policy  development  regarding  EBI  sustainability,  health  system  supports  for  integrating  social  determinants  of  health  into  HIV  services,  and  advancing  our  understanding  and  application  of  implementation  science  frameworks  across  contexts.  Facilitating  the  translation  of  research  findings  into  sustainable  programming  in  routine  practice  settings  will  require  embracing  the  dynamic  complexity  of  implementation  contexts  and  planning  for  sustainability  throughout  the  entire  research  process.  This  work  contributes  meaningfully  to  bridging  the  know-do  gap,  ultimately  working  to  ensure  that  effective  interventions  reach  the  communities  that  need  them  most.
■590    ▼aSchool  code:  0250.
■650  4▼aPublic  health
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■71020▼aUniversity  of  Washington▼bGlobal  Health.
■7730  ▼tDissertations  Abstracts  International▼g87-01B.
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■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17358393▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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