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Varied Environmental Exposure Measurement Methods and Their Effects on Health Risk Assessment of Birth Outcomes
Varied Environmental Exposure Measurement Methods and Their Effects on Health Risk Assessm...
Varied Environmental Exposure Measurement Methods and Their Effects on Health Risk Assessment of Birth Outcomes

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자료유형  
 학위논문 서양
최종처리일시  
20260202105635
ISBN  
9798297962781
DDC  
910
저자명  
Ramesh, Balaji.
서명/저자  
Varied Environmental Exposure Measurement Methods and Their Effects on Health Risk Assessment of Birth Outcomes
발행사항  
[Sl] : The Ohio State University, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
210 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-05, Section: A.
주기사항  
Advisor: Hyder, Ayaz;Hoet, Armando.
학위논문주기  
Thesis (Ph.D.)--The Ohio State University, 2025.
초록/해제  
요약Unsustainable human development leads to short-term health hazards like air pollution, and long-term consequences like climate change, which increase the frequency and severity hazards like extreme weather events (e.g., floods). Quantifying human exposure to these hazards is challenging due to the broad geographic impact of such hazards but is crucial for informing policies that protect human health. This dissertation applies and compares traditional exposure assessment methods with emerging/updated techniques that utilize dense networks of low-cost sensors and/or satellite observations to generate more refined exposure estimates, aimed at evaluating the relationship between environmental exposures and adverse birth outcomes (e.g., pregnancy complications, preterm birth, and low birth weight). It also provides an examination of how variations in exposure assessment methods and model configurations influence the estimation of associations between environmental exposures and birth outcomes.This dissertation investigates two environmental exposures, each in different study regions: floods caused by Hurricane Harvey in Texas in 2017, and fine particulate matter pollution (PM2.5) in Franklin County, Ohio from 2018 to 2023. Satellite-derived flood extent data were used to quantify flood exposure, while PM2.5 exposure was estimated by integrating low-cost sensor data with satellite observations using machine learning techniques. Data on birth outcomes have been collected from emergency department visits in Texas and birth certificates in Ohio. The association between the environmental exposure and adverse birth outcomes were estimated using statistical models, comparing the updated and traditional exposure assessment techniques. Additionally, the impact of geographic scale and spatial configuration of statistical models on the association between flood and adverse birth outcomes was examined.The results show that the health risk estimate for adverse birth outcomes associated with environmental exposures was similar using the updated and the traditional exposure assessment techniques. While this finding was observed for both environmental exposures assessed: floods and particulate matter pollution, for floods, the updated exposure assessment technique of combining remote-sensing products with different spatial and temporal resolutions identified additional areas where the flood-related ED visits for pregnancy complications were elevated compared to the traditional exposure assessment technique of using a single remote-sensing inundation product. For PM2.5, the updated exposure assessment technique using low-cost monitor observations integrated with satellite observations revealed a stronger association between first-trimester exposure and preterm birth compared to the traditional exposure assessment technique of PM2.5 observations from sparsely distributed EPA regulatory monitors.Additional findings revealed that using spatial models to account for spatial autocorrelation yielded nearly identical health risk estimates compared to those from non-spatial models in case of association between floods and ED visits for pregnancy complications. We have shown that this similarity could be due to the difference-in-differences study design used here, which compares changes over time between the exposed and control groups. In contrast, under a cross-sectional study design, spatial autocorrelation in model residuals led to significant differences in health risk estimates between spatial and non-spatial models.These findings advance exposure assessment methods by evaluating the emerging methods and improving our understanding of the magnitude of adverse health outcomes associated with environmental exposures. Compared to traditional approaches, the emerging methods assessed offer important advantages, especially the availability of data in near real time, which can support timely disaster response and risk assessment. The findings of this dissertation should also assist policymakers by more accurately estimating the true health risks and costs associated with health risks, which may have been underestimated by using traditional environmental exposure assessment methods. These findings should assist researchers by providing the trade-offs between different environmental exposure methods and geographic scale of analysis in terms of bias, complexity of the methods, data generation cost, and computational cost.
일반주제명  
Geography
일반주제명  
Public health
일반주제명  
Environmental health
일반주제명  
Remote sensing
키워드  
Environmental exposure
키워드  
Spatial epidemiology
키워드  
Fine particulate matter pollution
키워드  
Floods
키워드  
Adverse birth outcomes
키워드  
Satellite observations
기타저자  
The Ohio State University Public Health
기본자료저록  
Dissertations Abstracts International. 87-05A.
전자적 위치 및 접속  
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MARC

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■1001  ▼aRamesh,  Balaji.
■24510▼aVaried  Environmental  Exposure  Measurement  Methods  and  Their  Effects  on  Health  Risk  Assessment  of  Birth  Outcomes
■260    ▼a[Sl]▼bThe  Ohio  State  University▼c2025
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■300    ▼a210  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-05,  Section:  A.
■500    ▼aAdvisor:  Hyder,  Ayaz;Hoet,  Armando.
■5021  ▼aThesis  (Ph.D.)--The  Ohio  State  University,  2025.
■520    ▼aUnsustainable  human  development  leads  to  short-term  health  hazards  like  air  pollution,  and  long-term  consequences  like  climate  change,  which  increase  the  frequency  and  severity  hazards  like  extreme  weather  events  (e.g.,  floods).  Quantifying  human  exposure  to  these  hazards  is  challenging  due  to  the  broad  geographic  impact  of  such  hazards  but  is  crucial  for  informing  policies  that  protect  human  health.  This  dissertation  applies  and  compares  traditional  exposure  assessment  methods  with  emerging/updated  techniques  that  utilize  dense  networks  of  low-cost  sensors  and/or  satellite  observations  to  generate  more  refined  exposure  estimates,  aimed  at  evaluating  the  relationship  between  environmental  exposures  and  adverse  birth  outcomes  (e.g.,  pregnancy  complications,  preterm  birth,  and  low  birth  weight).  It  also  provides  an  examination  of  how  variations  in  exposure  assessment  methods  and  model  configurations  influence  the  estimation  of  associations  between  environmental  exposures  and  birth  outcomes.This  dissertation  investigates  two  environmental  exposures,  each  in  different  study  regions:  floods  caused  by  Hurricane  Harvey  in  Texas  in  2017,  and  fine  particulate  matter  pollution  (PM2.5)  in  Franklin  County,  Ohio  from  2018  to  2023.  Satellite-derived  flood  extent  data  were  used  to  quantify  flood  exposure,  while  PM2.5  exposure  was  estimated  by  integrating  low-cost  sensor  data  with  satellite  observations  using  machine  learning  techniques.  Data  on  birth  outcomes  have been  collected  from  emergency  department  visits  in  Texas  and  birth  certificates  in  Ohio.  The  association  between  the  environmental  exposure  and  adverse  birth  outcomes  were  estimated  using  statistical  models,  comparing  the  updated  and  traditional  exposure  assessment  techniques.  Additionally,  the  impact  of  geographic  scale  and  spatial  configuration  of  statistical  models  on  the  association  between  flood  and  adverse  birth  outcomes  was  examined.The  results  show  that  the  health  risk  estimate  for  adverse  birth  outcomes  associated  with  environmental  exposures  was  similar  using  the  updated  and  the  traditional  exposure  assessment  techniques.  While  this  finding  was  observed  for  both  environmental  exposures  assessed:  floods  and  particulate  matter  pollution,  for  floods,  the  updated  exposure  assessment  technique  of  combining  remote-sensing  products  with  different  spatial  and  temporal  resolutions  identified  additional  areas  where  the  flood-related  ED  visits  for  pregnancy  complications  were  elevated  compared  to  the  traditional  exposure  assessment  technique  of  using  a  single  remote-sensing  inundation  product.  For  PM2.5,  the  updated  exposure  assessment  technique  using  low-cost  monitor  observations  integrated  with  satellite  observations  revealed  a  stronger  association  between  first-trimester  exposure  and  preterm  birth  compared  to  the  traditional  exposure  assessment  technique  of  PM2.5  observations  from  sparsely  distributed  EPA  regulatory  monitors.Additional  findings  revealed  that  using  spatial  models  to  account  for  spatial  autocorrelation  yielded  nearly  identical  health  risk  estimates  compared  to  those  from  non-spatial  models  in  case  of  association  between  floods  and  ED  visits  for  pregnancy  complications.  We  have  shown  that  this  similarity  could  be  due  to  the  difference-in-differences  study  design  used  here, which  compares  changes  over  time  between  the  exposed  and  control  groups.  In  contrast,  under  a  cross-sectional  study  design,  spatial  autocorrelation  in  model  residuals  led  to  significant  differences  in  health  risk  estimates  between  spatial  and  non-spatial  models.These  findings  advance  exposure  assessment  methods  by  evaluating  the  emerging  methods  and  improving  our  understanding  of  the  magnitude  of  adverse  health  outcomes  associated  with  environmental  exposures.  Compared  to  traditional  approaches,  the  emerging  methods  assessed  offer  important  advantages,  especially  the  availability  of  data  in  near  real  time,  which  can  support  timely  disaster  response  and  risk  assessment.  The  findings  of  this  dissertation  should  also  assist  policymakers  by  more  accurately  estimating  the  true  health  risks  and  costs  associated  with  health  risks,  which  may  have  been  underestimated  by  using  traditional  environmental  exposure  assessment  methods.  These  findings  should  assist  researchers  by  providing  the  trade-offs  between  different  environmental  exposure  methods  and  geographic  scale  of  analysis  in  terms  of  bias,  complexity  of  the  methods,  data  generation  cost,  and  computational  cost.
■590    ▼aSchool  code:  0168.
■650  4▼aGeography
■650  4▼aPublic  health
■650  4▼aEnvironmental  health
■650  4▼aRemote  sensing
■653    ▼aEnvironmental  exposure
■653    ▼aSpatial  epidemiology
■653    ▼aFine  particulate  matter  pollution
■653    ▼aFloods
■653    ▼aAdverse  birth  outcomes
■653    ▼aSatellite  observations
■690    ▼a0366
■690    ▼a0470
■690    ▼a0573
■690    ▼a0799
■71020▼aThe  Ohio  State  University▼bPublic  Health.
■7730  ▼tDissertations  Abstracts  International▼g87-05A.
■790    ▼a0168
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17360904▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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