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Data-Driven Modeling of Pathological Mechanisms of Dyspnea in Heart Failure
Data-Driven Modeling of Pathological Mechanisms of Dyspnea in Heart Failure
Data-Driven Modeling of Pathological Mechanisms of Dyspnea in Heart Failure

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자료유형  
 학위논문 서양
최종처리일시  
20260202103021
ISBN  
9798314832653
DDC  
610.73
저자명  
Kraevsky-Phillips, Karina.
서명/저자  
Data-Driven Modeling of Pathological Mechanisms of Dyspnea in Heart Failure
발행사항  
[Sl] : University of Pittsburgh, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
159 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-11, Section: B.
주기사항  
Advisor: Henker, Richard.
학위논문주기  
Thesis (Ph.D.)--University of Pittsburgh, 2025.
초록/해제  
요약Dyspnea, or difficulty breathing, is one of the leading reasons for seeking emergency care among the six million Americans struggling to live with chronic heart failure in the US. Current clinical risk scores used in the emergency departments are neither sensitive nor specific in triaging dyspnea in these patients, which could delay life-saving therapeutics from those in utmost need or lead to unnecessary admissions and excessive diagnostic testing in those with benign underlying etiologies of dyspnea. This project aims to develop a data-driven clinical decision support tool to triage and phenotype the underlying etiology of dyspnea as well as risk-stratify patients with a known history of heart failure seeking emergency care, potentially improving patient outcomes, and reducing associated healthcare costs. The three manuscripts shaping the deliverables for this project reflect two of three specific aims: 1) scoping review of literature regarding risk stratification and prognostication tools for patients with HF during acute events; 2) manuscript describing the diagnostic decision support tool that denotes the likelihood of the underlying dyspnea source based on clinically meaningful data elements available during initial ED triage; and 3) manuscript describing an intelligent risk stratification tool to triage severity of illness in patients with HF presenting to the ED with dyspnea.
일반주제명  
Nursing
일반주제명  
Medicine
일반주제명  
Health sciences
일반주제명  
Pathology
키워드  
Data science
키워드  
Dyspnea
키워드  
Emergency departments
키워드  
Heart failure
키워드  
Pathological mechanisms
기타저자  
University of Pittsburgh Nursing
기본자료저록  
Dissertations Abstracts International. 86-11B.
전자적 위치 및 접속  
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MARC

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■24510▼aData-Driven  Modeling  of  Pathological  Mechanisms  of  Dyspnea  in  Heart  Failure
■260    ▼a[Sl]▼bUniversity  of  Pittsburgh▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a159  p
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■5021  ▼aThesis  (Ph.D.)--University  of  Pittsburgh,  2025.
■520    ▼aDyspnea,  or  difficulty  breathing,  is  one  of  the  leading  reasons  for  seeking  emergency  care  among  the  six  million  Americans  struggling  to  live  with  chronic  heart  failure  in  the  US.  Current  clinical  risk  scores  used  in  the  emergency  departments  are  neither  sensitive  nor  specific  in  triaging  dyspnea  in  these  patients,  which  could  delay  life-saving  therapeutics  from  those  in  utmost  need  or  lead  to  unnecessary  admissions  and  excessive  diagnostic  testing  in  those  with  benign  underlying  etiologies  of  dyspnea.  This  project  aims  to  develop  a  data-driven  clinical  decision  support  tool  to  triage  and  phenotype  the  underlying  etiology  of  dyspnea  as  well  as  risk-stratify  patients  with  a  known  history  of  heart  failure  seeking  emergency  care,  potentially  improving  patient  outcomes,  and  reducing  associated  healthcare  costs.  The  three  manuscripts  shaping  the  deliverables  for  this  project  reflect  two  of  three  specific  aims:  1)  scoping  review  of  literature  regarding  risk  stratification  and  prognostication  tools  for  patients  with  HF  during  acute  events;  2)  manuscript  describing  the  diagnostic  decision  support  tool  that  denotes  the  likelihood  of  the  underlying  dyspnea  source  based  on  clinically  meaningful  data  elements  available  during  initial  ED  triage;  and  3)  manuscript  describing  an  intelligent  risk  stratification  tool  to  triage  severity  of  illness  in  patients  with  HF  presenting  to  the  ED  with  dyspnea.
■590    ▼aSchool  code:  0178.
■650  4▼aNursing
■650  4▼aMedicine
■650  4▼aHealth  sciences
■650  4▼aPathology
■653    ▼aData  science
■653    ▼aDyspnea
■653    ▼aEmergency  departments
■653    ▼aHeart  failure
■653    ▼aPathological  mechanisms
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■71020▼aUniversity  of  Pittsburgh▼bNursing.
■7730  ▼tDissertations  Abstracts  International▼g86-11B.
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■792    ▼a2025
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■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17356709▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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