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Context-Dependent Value-Based Decision-Making Across Learning
Context-Dependent Value-Based Decision-Making Across Learning
Context-Dependent Value-Based Decision-Making Across Learning

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자료유형  
 학위논문 서양
최종처리일시  
20260202104724
ISBN  
9798293887521
DDC  
616
저자명  
Schiereck, Shannon.
서명/저자  
Context-Dependent Value-Based Decision-Making Across Learning
발행사항  
[Sl] : New York University, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
147 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-03, Section: B.
주기사항  
Advisor: Constantinople, Christine.
학위논문주기  
Thesis (Ph.D.)--New York University, 2025.
초록/해제  
요약Humans and other animals are thought to make choices between different options by evaluating and comparing their subjective values. Orbitofrontal cortex (OFC) has been implicated in value-based decision-making, especially when values must be inferred based on knowledge of the structure of the environment. However, the precise computation performed by OFC for state inference is unclear. In this thesis, I show that rats use distinct cognitive strategies to compute the subjective value of offered rewards at different stages of training. I then characterize neural dynamics in OFC at these different stages. We trained rats to perform a temporal wagering task with hidden states. Expert rats inferred the underlying reward state and updated their subjective beliefs about the value of reward offers based on the inferred state. Rats naive to the hidden states passively adapted to reward statistics. I found that inactivating OFC in expert rats impaired updating of subjective beliefs about states. Additionally, analysis of electrophysiology data revealed neural dynamics reflecting inferred states in rats performing inference, but not in rats using other strategies. This work identifies a precise computation performed by OFC and reveals neural signatures of hidden state inference.
일반주제명  
Neurosciences
일반주제명  
Health sciences
일반주제명  
Cognitive psychology
키워드  
Orbitofrontal cortex
키워드  
Cognitive strategies
키워드  
Electrophysiology
기타저자  
New York University Basic Medical Science
기본자료저록  
Dissertations Abstracts International. 87-03B.
전자적 위치 및 접속  
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MARC

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■035    ▼a(MiAaPQ)AAI32121903
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a616
■1001  ▼aSchiereck,  Shannon.
■24510▼aContext-Dependent  Value-Based  Decision-Making  Across  Learning
■260    ▼a[Sl]▼bNew  York  University▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a147  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-03,  Section:  B.
■500    ▼aAdvisor:  Constantinople,  Christine.
■5021  ▼aThesis  (Ph.D.)--New  York  University,  2025.
■520    ▼aHumans  and  other  animals  are  thought  to  make  choices  between  different  options  by  evaluating  and  comparing  their  subjective  values.  Orbitofrontal  cortex  (OFC)  has  been  implicated  in  value-based  decision-making,  especially  when  values  must  be  inferred  based  on  knowledge  of  the  structure  of  the  environment.  However,  the  precise  computation  performed  by  OFC  for  state  inference  is  unclear.  In  this  thesis,  I  show  that  rats  use  distinct  cognitive  strategies  to  compute  the  subjective  value  of  offered  rewards  at  different  stages  of  training.  I  then  characterize  neural  dynamics  in  OFC  at  these  different  stages.  We  trained  rats  to  perform  a  temporal  wagering  task  with  hidden  states.  Expert  rats  inferred  the  underlying  reward  state  and  updated  their  subjective  beliefs  about  the  value  of  reward  offers  based  on  the  inferred  state.  Rats  naive  to  the  hidden  states  passively  adapted  to  reward  statistics.  I  found  that  inactivating  OFC  in  expert  rats  impaired  updating  of  subjective  beliefs  about  states.  Additionally,  analysis  of  electrophysiology  data  revealed  neural  dynamics  reflecting  inferred  states  in  rats  performing  inference,  but  not  in  rats  using  other  strategies.  This  work  identifies  a  precise  computation  performed  by  OFC  and  reveals  neural  signatures  of  hidden  state  inference.
■590    ▼aSchool  code:  0146.
■650  4▼aNeurosciences
■650  4▼aHealth  sciences
■650  4▼aCognitive  psychology
■653    ▼aOrbitofrontal  cortex
■653    ▼aCognitive  strategies
■653    ▼aElectrophysiology
■690    ▼a0317
■690    ▼a0566
■690    ▼a0633
■71020▼aNew  York  University▼bBasic  Medical  Science.
■7730  ▼tDissertations  Abstracts  International▼g87-03B.
■790    ▼a0146
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17358598▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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