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Health-Related Social Needs and Cancer Burden in Persons Living With Human Immunodeficiency Virus
Health-Related Social Needs and Cancer Burden in Persons Living With Human Immunodeficiency Virus
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202104729
- ISBN
- 9798315778394
- DDC
- 614.4
- 저자명
- Zhou, Guangjin.
- 서명/저자
- Health-Related Social Needs and Cancer Burden in Persons Living With Human Immunodeficiency Virus
- 발행사항
- [Sl] : Case Western Reserve University, 2024
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2024
- 형태사항
- 165 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 86-12, Section: B.
- 주기사항
- Advisor: Koroukian, Siran M.;Spilsbury, James.
- 학위논문주기
- Thesis (Ph.D.)--Case Western Reserve University, 2024.
- 초록/해제
- 요약Objective: To assess the impact of health-related social needs (HRSN) on hospital readmission and cancer prevalence in persons living with HIV (PLWH). Study population and methods: For the HRSN work, I utilized four-year (2016-2019) longitudinal State Inpatient Databases (SID) from Florida and Maryland. The study encompassed 43,229 HIV patients in Florida and 12,396 in Maryland. For the cancer burden work, I used one-year nationwide Medicaid enrollment files. Cancer burden in men and women living with HIV were examined separately. The sample of men included 82,495 with HIV and 7,302,523 without HIV, and that of women included 72,508 with HIV and 17,353,963 without HIV. The traditional statistical and data mining approaches were used to analyze data. Results: Key findings include: (1) A significantly high prevalence of social needs was associated with increased PLWH hospital readmission, and these needs emerged as critical elements in predicting hospital readmission. (2) The spectrum of cancer burden differed by gender, but anal cancer and non-Hodgkin's lymphoma (NHL) were consistently among the most prevalent cancer types in both men and women. (3) Among men living with HIV, the prevalence of non-AIDS defining cancers was about twice that of men without HIV, with anal cancer and non-Hodgkin's lymphoma having the highest prevalence. (4) Among women living with HIV, cervical cancer, Kaposi's sarcoma, anal cancer, and Hodgkin's and non-Hodgkin's lymphoma remained highly prevalent. (5) Age had a more robust modification effect in younger HIV patients compared to the non-HIV population of same age range. Implications: This study both identified the pivotal role of health-related social needs in hospital readmission and elucidated cancer disparities in PLWH. It is imperative for healthcare providers and policymakers to acknowledge social factors as critical in reducing hospital readmissions for HIV patients. Recognizing cancer disparities is essential for developing targeted interventions and improving healthcare outcomes for both men and women living with HIV. Initiating HPV vaccination for anal and cervical cancer should target adolescents and young adults among HIV patients. Additionally, cancer prevention and screening should prioritize high-risk minority PLWH from an early age.
- 일반주제명
- Epidemiology
- 일반주제명
- Health sciences
- 일반주제명
- Immunology
- 기타저자
- Case Western Reserve University Clinical Research
- 기본자료저록
- Dissertations Abstracts International. 86-12B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a614.4
■1001 ▼aZhou, Guangjin.
■24510▼aHealth-Related Social Needs and Cancer Burden in Persons Living With Human Immunodeficiency Virus
■260 ▼a[Sl]▼bCase Western Reserve University▼c2024
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2024
■300 ▼a165 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 86-12, Section: B.
■500 ▼aAdvisor: Koroukian, Siran M.;Spilsbury, James.
■5021 ▼aThesis (Ph.D.)--Case Western Reserve University, 2024.
■520 ▼aObjective: To assess the impact of health-related social needs (HRSN) on hospital readmission and cancer prevalence in persons living with HIV (PLWH). Study population and methods: For the HRSN work, I utilized four-year (2016-2019) longitudinal State Inpatient Databases (SID) from Florida and Maryland. The study encompassed 43,229 HIV patients in Florida and 12,396 in Maryland. For the cancer burden work, I used one-year nationwide Medicaid enrollment files. Cancer burden in men and women living with HIV were examined separately. The sample of men included 82,495 with HIV and 7,302,523 without HIV, and that of women included 72,508 with HIV and 17,353,963 without HIV. The traditional statistical and data mining approaches were used to analyze data. Results: Key findings include: (1) A significantly high prevalence of social needs was associated with increased PLWH hospital readmission, and these needs emerged as critical elements in predicting hospital readmission. (2) The spectrum of cancer burden differed by gender, but anal cancer and non-Hodgkin's lymphoma (NHL) were consistently among the most prevalent cancer types in both men and women. (3) Among men living with HIV, the prevalence of non-AIDS defining cancers was about twice that of men without HIV, with anal cancer and non-Hodgkin's lymphoma having the highest prevalence. (4) Among women living with HIV, cervical cancer, Kaposi's sarcoma, anal cancer, and Hodgkin's and non-Hodgkin's lymphoma remained highly prevalent. (5) Age had a more robust modification effect in younger HIV patients compared to the non-HIV population of same age range. Implications: This study both identified the pivotal role of health-related social needs in hospital readmission and elucidated cancer disparities in PLWH. It is imperative for healthcare providers and policymakers to acknowledge social factors as critical in reducing hospital readmissions for HIV patients. Recognizing cancer disparities is essential for developing targeted interventions and improving healthcare outcomes for both men and women living with HIV. Initiating HPV vaccination for anal and cervical cancer should target adolescents and young adults among HIV patients. Additionally, cancer prevention and screening should prioritize high-risk minority PLWH from an early age.
■590 ▼aSchool code: 0042.
■650 4▼aEpidemiology
■650 4▼aHealth sciences
■650 4▼aImmunology
■653 ▼aHealth-related social needs
■653 ▼aState Inpatient Databases
■653 ▼aHuman Immunodeficiency Virus
■690 ▼a0766
■690 ▼a0566
■690 ▼a0982
■690 ▼a0769
■71020▼aCase Western Reserve University▼bClinical Research.
■7730 ▼tDissertations Abstracts International▼g86-12B.
■790 ▼a0042
■791 ▼aPh.D.
■792 ▼a2024
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17358636▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


