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Human Milk and Direct Breastfeeding for Infants With Single Ventricle Congenital Heart Disease: An Analysis of Prevalence, Supportive and Limiting Factors, and Impact on Key Outcomes
Human Milk and Direct Breastfeeding for Infants With Single Ventricle Congenital Heart Dis...
Human Milk and Direct Breastfeeding for Infants With Single Ventricle Congenital Heart Disease: An Analysis of Prevalence, Supportive and Limiting Factors, and Impact on Key Outcomes

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자료유형  
 학위논문 서양
최종처리일시  
20260209102833
ISBN  
9798291502808
DDC  
610.73
저자명  
Sybesma Elgersma, Kristin Marie.
서명/저자  
Human Milk and Direct Breastfeeding for Infants With Single Ventricle Congenital Heart Disease: An Analysis of Prevalence, Supportive and Limiting Factors, and Impact on Key Outcomes
발행사항  
[Sl] : University of Minnesota, 2023
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2023
형태사항  
268 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-02, Section: B.
주기사항  
Advisor: McKechnie, Anne Chevalier.
학위논문주기  
Thesis (Ph.D.)--University of Minnesota, 2023.
초록/해제  
요약BackgroundInfants with single ventricle congenital heart disease (SV CHD) undergo three staged palliative surgeries/interventions and are at risk for morbidity and mortality. Human milk (HM) and direct breastfeeding (BF) benefit other vulnerable neonates, but evidence about HM/BF for infants with SV CHD is limited. We aimed to:(1) Determine HM/BF prevalence; determine whether BF at neonatal stage 1 palliation (S1P) discharge is associated with continued HM feeding at stage 2 palliation (S2P).(2) Identify factors that support or limit HM and BF.(3) Estimate the effect of HM and BF on key health outcomes.MethodsWe analyzed data from the National Pediatric Cardiology Quality Improvement Collaborative Registry (n=2491 infants; n=68 sites; 2016-2021). Analysis involved:(1) Descriptive statistics for prevalence; adjusted logistic regression to examine associations between early BF/later HM.(2) Machine learning to identify key HM/BF predictors.(3) Poisson and logistic regression to compare outcomes between propensity-matched cohorts.Results(1) HM/BF prevalence was low and varied among sites. Infants BF at S1P discharge had 4.11 times greater odds of HM feeding at S2P.(2) The strongest HM/BF predictor domain areas included preoperative feeding, demographics and social determinants of health, feeding route, clinical course, and site.(3) Estimates for all outcomes were better in high HM/BF groups, including significantly lower odds of necrotizing enterocolitis, sepsis, and infection; shorter hospital length of stay; and lower mortality.ConclusionsIncreasing the dose and duration of HM and BF has strong potential to substantially improve the health outcomes of these vulnerable infants.
일반주제명  
Nursing
일반주제명  
Nutrition
일반주제명  
Epidemiology
키워드  
Breastfeeding
키워드  
Congenital heart disease
키워드  
Human milk
키워드  
Infants
키워드  
Single ventricle
기타저자  
University of Minnesota Nursing
기본자료저록  
Dissertations Abstracts International. 87-02B.
전자적 위치 및 접속  
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■00520260209102833
■006m          o    d                
■007cr#unu||||||||
■020    ▼a9798291502808
■035    ▼a(MiAaPQ)AAI30573825
■040    ▼aMiAaPQ▼cMiAaPQ
■0820  ▼a610.73
■1001  ▼aSybesma  Elgersma,  Kristin  Marie.
■24510▼aHuman  Milk  and  Direct  Breastfeeding  for  Infants  With  Single  Ventricle  Congenital  Heart  Disease:  An  Analysis  of  Prevalence,  Supportive  and  Limiting  Factors,  and  Impact  on  Key  Outcomes
■260    ▼a[Sl]▼bUniversity  of  Minnesota▼c2023
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2023
■300    ▼a268  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-02,  Section:  B.
■500    ▼aAdvisor:  McKechnie,  Anne  Chevalier.
■5021  ▼aThesis  (Ph.D.)--University  of  Minnesota,  2023.
■520    ▼aBackgroundInfants  with  single  ventricle  congenital  heart  disease  (SV  CHD)  undergo  three  staged  palliative  surgeries/interventions  and  are  at  risk  for  morbidity  and  mortality.  Human  milk  (HM)  and  direct  breastfeeding  (BF)  benefit  other  vulnerable  neonates,  but  evidence  about  HM/BF  for  infants  with  SV  CHD  is  limited.  We  aimed  to:(1)  Determine  HM/BF  prevalence;  determine  whether  BF  at  neonatal  stage  1  palliation  (S1P)  discharge  is  associated  with  continued  HM  feeding  at  stage  2  palliation  (S2P).(2)  Identify  factors  that  support  or  limit  HM  and  BF.(3)  Estimate  the  effect  of  HM  and  BF  on  key  health  outcomes.MethodsWe  analyzed  data  from  the  National  Pediatric  Cardiology  Quality  Improvement  Collaborative  Registry  (n=2491  infants;  n=68  sites;  2016-2021).  Analysis  involved:(1)  Descriptive  statistics  for  prevalence;  adjusted  logistic  regression  to  examine  associations  between  early  BF/later  HM.(2)  Machine  learning  to  identify  key  HM/BF  predictors.(3)  Poisson  and  logistic  regression  to  compare  outcomes  between  propensity-matched  cohorts.Results(1)  HM/BF  prevalence  was  low  and  varied  among  sites.  Infants  BF  at  S1P  discharge  had  4.11  times  greater  odds  of  HM  feeding  at  S2P.(2)  The  strongest  HM/BF  predictor  domain  areas  included  preoperative  feeding,  demographics  and  social  determinants  of  health,  feeding  route,  clinical  course,  and  site.(3)  Estimates  for  all  outcomes  were  better  in  high  HM/BF  groups,  including  significantly  lower  odds  of  necrotizing  enterocolitis,  sepsis,  and  infection;  shorter  hospital  length  of  stay;  and  lower  mortality.ConclusionsIncreasing  the  dose  and  duration  of  HM  and  BF  has  strong  potential  to  substantially  improve  the  health  outcomes  of  these  vulnerable  infants.
■590    ▼aSchool  code:  0130.
■650  4▼aNursing
■650  4▼aNutrition
■650  4▼aEpidemiology
■653    ▼aBreastfeeding
■653    ▼aCongenital  heart  disease
■653    ▼aHuman  milk
■653    ▼aInfants
■653    ▼aSingle  ventricle
■690    ▼a0569
■690    ▼a0570
■690    ▼a0766
■71020▼aUniversity  of  Minnesota▼bNursing.
■7730  ▼tDissertations  Abstracts  International▼g87-02B.
■790    ▼a0130
■791    ▼aPh.D.
■792    ▼a2023
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17365830▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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