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Reducing Opioid Use Following Posterior Spinal Fusion Procedures: A Pilot Project
Reducing Opioid Use Following Posterior Spinal Fusion Procedures: A Pilot Project
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202103512
- ISBN
- 9798288806421
- DDC
- 610.73
- 저자명
- Cornett, Kevin.
- 서명/저자
- Reducing Opioid Use Following Posterior Spinal Fusion Procedures: A Pilot Project
- 발행사항
- [Sl] : Yale University, 2025
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2025
- 형태사항
- 61 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 87-01, Section: B.
- 주기사항
- Advisor: Feder, Shelli.
- 학위논문주기
- Thesis (D.N.P.)--Yale University, 2025.
- 초록/해제
- 요약Importance: Opioid misuse and mortality remain a prevalent problem in the United States and there is a high rate of chronic opioid-use after spinal fusions. Current guidelines recommend the optimization of non-opioid analgesics as a primary pain control strategy with opioids acting as a secondary agent.Objective: To pilot an analgesic decision tree (ADT) featuring non-opioid analgesics to reduce postoperative pain, opioid consumption, and the incidence of adverse events during the first 48 hours after patients undergo a posterior spinal fusion.Methods: A literature review of opioid-sparing analgesics was conducted and a protocol developed as an interdisciplinary collaboration. The ADT was piloted in an intensive care unit for 10 weeks. Pain control, opioid consumption, and the incidence of adverse events were compared to historical controls from a previous 10-week period.Results: In total, 12 historical control charts were reviewed and 17 patients enrolled in the ADT group. There was no significant difference in groups. The ADT did not affect NRS scores, CPOT scores, MME consumption, or ORAE in a statistically significant way. Power analyses indicate that a minimum of 9894 patients are required to detect significance.Conclusions: The ADT may be non-inferior in pain control and opioid consumption, but future testing is required. Further pilots should control confounding influences to optimize power analyses. Subsequent projects should utilize these power analyses to determine the ADT's influence on pain control, opioid consumption, and adverse event incidence.
- 일반주제명
- Nursing
- 일반주제명
- Pharmacology
- 일반주제명
- Medicine
- 일반주제명
- Surgery
- 키워드
- Opioid misuse
- 키워드
- Pain control
- 기타저자
- Yale University Yale University School of Nursing
- 기본자료저록
- Dissertations Abstracts International. 87-01B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■006m o d
■007cr#unu||||||||
■020 ▼a9798288806421
■035 ▼a(MiAaPQ)AAI32003509
■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a610.73
■1001 ▼aCornett, Kevin.
■24510▼aReducing Opioid Use Following Posterior Spinal Fusion Procedures: A Pilot Project
■260 ▼a[Sl]▼bYale University▼c2025
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a61 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 87-01, Section: B.
■500 ▼aAdvisor: Feder, Shelli.
■5021 ▼aThesis (D.N.P.)--Yale University, 2025.
■520 ▼aImportance: Opioid misuse and mortality remain a prevalent problem in the United States and there is a high rate of chronic opioid-use after spinal fusions. Current guidelines recommend the optimization of non-opioid analgesics as a primary pain control strategy with opioids acting as a secondary agent.Objective: To pilot an analgesic decision tree (ADT) featuring non-opioid analgesics to reduce postoperative pain, opioid consumption, and the incidence of adverse events during the first 48 hours after patients undergo a posterior spinal fusion.Methods: A literature review of opioid-sparing analgesics was conducted and a protocol developed as an interdisciplinary collaboration. The ADT was piloted in an intensive care unit for 10 weeks. Pain control, opioid consumption, and the incidence of adverse events were compared to historical controls from a previous 10-week period.Results: In total, 12 historical control charts were reviewed and 17 patients enrolled in the ADT group. There was no significant difference in groups. The ADT did not affect NRS scores, CPOT scores, MME consumption, or ORAE in a statistically significant way. Power analyses indicate that a minimum of 9894 patients are required to detect significance.Conclusions: The ADT may be non-inferior in pain control and opioid consumption, but future testing is required. Further pilots should control confounding influences to optimize power analyses. Subsequent projects should utilize these power analyses to determine the ADT's influence on pain control, opioid consumption, and adverse event incidence.
■590 ▼aSchool code: 0265.
■650 4▼aNursing
■650 4▼aPharmacology
■650 4▼aMedicine
■650 4▼aSurgery
■653 ▼aOpioid misuse
■653 ▼aPosterior spinal fusion
■653 ▼aAnalgesic decision tree
■653 ▼aPain control
■653 ▼aOpioid consumption
■690 ▼a0569
■690 ▼a0576
■690 ▼a0564
■690 ▼a0419
■71020▼aYale University▼bYale University School of Nursing.
■7730 ▼tDissertations Abstracts International▼g87-01B.
■790 ▼a0265
■791 ▼aD.N.P.
■792 ▼a2025
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17357438▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.
