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Worse Than Death? The Older Patient and Long-Term Outcomes After Emergency General Surgery
Worse Than Death? The Older Patient and Long-Term Outcomes After Emergency General Surgery
Worse Than Death? The Older Patient and Long-Term Outcomes After Emergency General Surgery

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자료유형  
 학위논문 서양
최종처리일시  
20260209102842
ISBN  
9798315778127
DDC  
610
저자명  
Ho, Vanessa Phillis.
서명/저자  
Worse Than Death? The Older Patient and Long-Term Outcomes After Emergency General Surgery
발행사항  
[Sl] : Case Western Reserve University, 2023
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2023
형태사항  
182 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-12, Section: B.
주기사항  
Advisor: Spilsbury, James.
학위논문주기  
Thesis (Ph.D.)--Case Western Reserve University, 2023.
초록/해제  
요약The purpose of this dissertation is to explore baseline and acute health vulnerability factors in older patients with emergency general surgery (EGS) conditions and assess the relationships between these factors and long-term outcomes. EGS conditions, such as gastrointestinal perforation and ischemia, are life-threatening conditions which lead to 3 million admissions per year in the United States. Older adults bear a disproportionate burden of EGS case volume and morbidity, and this will become more pronounced as the population ages. Many older EGS patients already have a baseline level of aging-related health vulnerability, defined as diseases, functional limitations, social needs, and other aging-related concerns which cause declines in mental and physical health. Our current knowledge about how preexisting health vulnerability affects outcomes in EGS patients is limited.In this dissertation, I explore the interaction between baseline health vulnerability factors and acute health factors to identify and quantify factors which contribute meaningfully to post-EGS recovery. To approach this aim, I performed research using quantitative and qualitative research methods, designed to explore effects of multiple aging-related health vulnerability domains on long-term outcomes after EGS. Our central hypothesis is that specific health vulnerability factors will be meaningful for long-term outcomes in older EGS patients.This research identified several key takeaway points. Health vulnerability was entwined with the development of EGS diseases (older EGS patients had higher levels of vulnerability than non-EGS patients), use of operative management (vulnerable EGS patients were less likely to receive operations), and outcomes (vulnerable EGS patients had poorer survival). Our quantitative and qualitative work identified that functional status was both a key prognostication factor for survival and a meaningful recovery goal. Our qualitative work also identified that older EGS patients rely strongly on their social networks and support systems in the postoperative recovery period.The foundational work presented in this dissertation provides important knowledge regarding the relationships between aging-related health vulnerability and long-term outcomes in older patients with EGS conditions. I look forward to continuing this work throughout my career and develop strategies to improve alignment between patient goals and long-term health in older EGS patients.
일반주제명  
Medicine
일반주제명  
Surgery
일반주제명  
Aging
키워드  
Emergency surgery
키워드  
Emergency general surgery
키워드  
Patient-centered outcomes
키워드  
Mixed methods research
키워드  
EGS patients
기타저자  
Case Western Reserve University Clinical Translational Science
기본자료저록  
Dissertations Abstracts International. 86-12B.
전자적 위치 및 접속  
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MARC

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■0820  ▼a610
■1001  ▼aHo,  Vanessa  Phillis.
■24510▼aWorse  Than  Death?  The  Older  Patient  and  Long-Term  Outcomes  After  Emergency  General  Surgery
■260    ▼a[Sl]▼bCase  Western  Reserve  University▼c2023
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2023
■300    ▼a182  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-12,  Section:  B.
■500    ▼aAdvisor:  Spilsbury,  James.
■5021  ▼aThesis  (Ph.D.)--Case  Western  Reserve  University,  2023.
■520    ▼aThe  purpose  of  this  dissertation  is  to  explore  baseline  and  acute  health  vulnerability  factors  in  older  patients  with  emergency  general  surgery  (EGS)  conditions  and  assess  the  relationships  between  these  factors  and  long-term  outcomes.  EGS  conditions,  such  as  gastrointestinal  perforation  and  ischemia,  are  life-threatening  conditions  which  lead  to  3  million  admissions  per  year  in  the  United  States.  Older  adults  bear  a  disproportionate  burden  of  EGS  case  volume  and  morbidity,  and  this  will  become  more  pronounced  as  the  population  ages.  Many  older  EGS  patients  already  have  a  baseline  level  of  aging-related  health  vulnerability,  defined  as  diseases,  functional  limitations,  social  needs,  and  other  aging-related  concerns  which  cause  declines  in  mental  and  physical  health.  Our  current  knowledge  about  how  preexisting  health  vulnerability  affects  outcomes  in  EGS  patients  is  limited.In  this  dissertation,  I  explore  the  interaction  between  baseline  health  vulnerability  factors  and  acute  health  factors  to  identify  and  quantify  factors  which  contribute  meaningfully  to  post-EGS  recovery.  To  approach  this  aim,  I  performed  research  using  quantitative  and  qualitative  research  methods,  designed  to  explore  effects  of  multiple  aging-related  health  vulnerability  domains  on  long-term  outcomes  after  EGS.  Our  central  hypothesis  is  that  specific  health  vulnerability  factors  will  be  meaningful  for  long-term  outcomes  in  older  EGS  patients.This  research  identified  several  key  takeaway  points.  Health  vulnerability  was  entwined  with  the  development  of  EGS  diseases  (older  EGS  patients  had  higher  levels  of  vulnerability  than  non-EGS  patients),  use  of  operative  management  (vulnerable  EGS  patients  were  less  likely  to  receive  operations),  and  outcomes  (vulnerable  EGS  patients  had  poorer  survival).  Our  quantitative  and  qualitative  work  identified  that  functional  status  was  both  a  key  prognostication  factor  for  survival  and  a  meaningful  recovery  goal.  Our  qualitative  work  also  identified  that  older  EGS  patients  rely  strongly  on  their  social  networks  and  support  systems  in  the  postoperative  recovery  period.The  foundational  work  presented  in  this  dissertation  provides  important  knowledge  regarding  the  relationships  between  aging-related  health  vulnerability  and  long-term  outcomes  in  older  patients  with  EGS  conditions.  I  look  forward  to  continuing  this  work  throughout  my  career  and  develop  strategies  to  improve  alignment  between  patient  goals  and  long-term  health  in  older  EGS  patients.
■590    ▼aSchool  code:  0042.
■650  4▼aMedicine
■650  4▼aSurgery
■650  4▼aAging
■653    ▼aEmergency  surgery
■653    ▼aEmergency  general  surgery
■653    ▼aPatient-centered  outcomes
■653    ▼aMixed  methods  research
■653    ▼aEGS  patients
■690    ▼a0564
■690    ▼a0769
■690    ▼a0576
■690    ▼a0493
■71020▼aCase  Western  Reserve  University▼bClinical  Translational  Science.
■7730  ▼tDissertations  Abstracts  International▼g86-12B.
■790    ▼a0042
■791    ▼aPh.D.
■792    ▼a2023
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17365867▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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