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Investigating Cochlear Responses Using a Physiologically Based Model
Investigating Cochlear Responses Using a Physiologically Based Model
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260202105526
- ISBN
- 9798263344016
- DDC
- 500
- 서명/저자
- Investigating Cochlear Responses Using a Physiologically Based Model
- 발행사항
- [Sl] : Georgia Institute of Technology, 2025
- 발행사항
- Ann Arbor : ProQuest Dissertations & Theses, 2025
- 형태사항
- 123 p
- 주기사항
- Source: Dissertations Abstracts International, Volume: 87-05, Section: B.
- 주기사항
- Advisor: Meaud, Julien.
- 학위논문주기
- Thesis (Ph.D.)--Georgia Institute of Technology, 2025.
- 초록/해제
- 요약The mammalian cochlea bestows humans and other mammals with remarkable hearing ability over a wide range of frequencies and stimulus levels. This is achieved in part through an active feedback mechanism, termed the cochlear amplifier, which boosts the cochlear response to low-level stimuli. Cutting edge experiments over the last few decades have probed mechanical and electrical responses inside the cochlea with unprecedented detail. These studies have shown that the organ of Corti, which is a strip of cellular and structural components in the cochlea that mediates sound transduction to nerve signals, exhibits complex relative motions rather than rigid body motion as previously thought. In turn, these new findings have challenged traditional theories about how the cochlear amplifier, which is facilitated by outer hair cells in the organ of Corti, functions. In this dissertation, a computational model of the mammalian cochlea is implemented with a reformulated structural model of the organ of Corti that improves the feasibility of changes to model assumptions. The model is used to show that compliance of some structural elements of the organ of Corti leads to complex motion between organ of Corti structures. Furthermore, the Deiters' cells in the organ of Corti are made much more compliant than the basilar membrane, based on new evidence. The influence of this more realistic compliance on power transfer to cochlear traveling waves is evaluated. The results of this study challenge the traditional theory of how outer hair cells amplify cochlear responses, which is that they apply a force directly on the basilar membrane through rigid Deiters' cells, and a new theory of how they may do so is presented. By expanding model assumptions based on experimental evidence, and characterizing power delivery of the cochlear amplifier, the research in this thesis expands understanding of cochlear mechanics.
- 일반주제명
- Kinematics
- 일반주제명
- Tomography
- 일반주제명
- Mechanics
- 일반주제명
- Eardrum
- 일반주제명
- Electricity generation
- 일반주제명
- Hearing protection
- 일반주제명
- Electric power
- 일반주제명
- Audiology
- 일반주제명
- Fluid mechanics
- 일반주제명
- Medical imaging
- 기본자료저록
- Dissertations Abstracts International. 87-05B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■040 ▼aMiAaPQ▼cMiAaPQ
■0820 ▼a500
■1001 ▼aSamaras, Georgios.
■24510▼aInvestigating Cochlear Responses Using a Physiologically Based Model
■260 ▼a[Sl]▼bGeorgia Institute of Technology▼c2025
■260 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a123 p
■500 ▼aSource: Dissertations Abstracts International, Volume: 87-05, Section: B.
■500 ▼aAdvisor: Meaud, Julien.
■5021 ▼aThesis (Ph.D.)--Georgia Institute of Technology, 2025.
■520 ▼aThe mammalian cochlea bestows humans and other mammals with remarkable hearing ability over a wide range of frequencies and stimulus levels. This is achieved in part through an active feedback mechanism, termed the cochlear amplifier, which boosts the cochlear response to low-level stimuli. Cutting edge experiments over the last few decades have probed mechanical and electrical responses inside the cochlea with unprecedented detail. These studies have shown that the organ of Corti, which is a strip of cellular and structural components in the cochlea that mediates sound transduction to nerve signals, exhibits complex relative motions rather than rigid body motion as previously thought. In turn, these new findings have challenged traditional theories about how the cochlear amplifier, which is facilitated by outer hair cells in the organ of Corti, functions. In this dissertation, a computational model of the mammalian cochlea is implemented with a reformulated structural model of the organ of Corti that improves the feasibility of changes to model assumptions. The model is used to show that compliance of some structural elements of the organ of Corti leads to complex motion between organ of Corti structures. Furthermore, the Deiters' cells in the organ of Corti are made much more compliant than the basilar membrane, based on new evidence. The influence of this more realistic compliance on power transfer to cochlear traveling waves is evaluated. The results of this study challenge the traditional theory of how outer hair cells amplify cochlear responses, which is that they apply a force directly on the basilar membrane through rigid Deiters' cells, and a new theory of how they may do so is presented. By expanding model assumptions based on experimental evidence, and characterizing power delivery of the cochlear amplifier, the research in this thesis expands understanding of cochlear mechanics.
■590 ▼aSchool code: 0078.
■650 4▼aKinematics
■650 4▼aTomography
■650 4▼aFluid-structure interaction
■650 4▼aMechanics
■650 4▼aEardrum
■650 4▼aElectricity generation
■650 4▼aHearing protection
■650 4▼aElectric power
■650 4▼aAudiology
■650 4▼aFluid mechanics
■650 4▼aMedical imaging
■690 ▼a0346
■690 ▼a0300
■690 ▼a0204
■690 ▼a0574
■71020▼aGeorgia Institute of Technology.
■7730 ▼tDissertations Abstracts International▼g87-05B.
■790 ▼a0078
■791 ▼aPh.D.
■792 ▼a2025
■793 ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17360436▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


