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Uncertainty Analysis in ICRP 66 Human Respiratory Tract Model for Consequence Management Data Products
Uncertainty Analysis in ICRP 66 Human Respiratory Tract Model for Consequence Management D...
Uncertainty Analysis in ICRP 66 Human Respiratory Tract Model for Consequence Management Data Products

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자료유형  
 학위논문 서양
최종처리일시  
20260202105604
ISBN  
9798265401410
DDC  
001
저자명  
Margot, Dmitri Edward.
서명/저자  
Uncertainty Analysis in ICRP 66 Human Respiratory Tract Model for Consequence Management Data Products
발행사항  
[Sl] : Georgia Institute of Technology, 2024
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2024
형태사항  
227 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-05, Section: B.
주기사항  
Advisor: Dewji, Shaheen.
학위논문주기  
Thesis (Ph.D.)--Georgia Institute of Technology, 2024.
초록/해제  
요약Inhaled radioactive is a unique hazard. Once inhaled the radioactive material is translocated within the body via incorporation into the metabolism and immune response. While metabolizing, the radioactive material is irradiating nearby tissue. Since the distribution of radioactive material changes over time, biokinetic modelling tracks the movement of the radioactive material within organs and tissues. To determine the impact of the input parameters into biokinetic modelling, a software called REDCAL (Radiation Exposure Dose Calculator) was developed in Python to handle statistically sampled parameters to compute the radiation dose from radionuclides of concern for emergency response planners. REDCAL handles the inhalation of radioactive particles and subsequent deposition within the airways. Following the deposition computations, REDCAL tracks the movement of radioactive material within the body and computes the effective dose to the individual over a lifetime. With statistically sampled input parameters, REDCAL was used to generate 3,410,000 effective dose coefficients to analyze the influence of the input parameters on the resulting dose. As sets of dose coefficients were made for each radionuclide and its associated lung clearance type(s), a defined distribution of its effective dose coefficient as a function of inhaled particle size, in AMAD, were generated to inform the sampling needing for computing derived response levels (DRLs) by in Turbo FRMAC by the Federal Radiological Monitoring and Assessment Center (FRMAC). This dissertation covers the methods, mathematics, and concepts required to compute particle deposition in the airways, solve biokinetic models, and compute effective dose from radiation sources with time-dependent concentrations.
일반주제명  
Software
일반주제명  
Iodine
일반주제명  
Radiation protection
일반주제명  
Chemical elements
일반주제명  
Lymphatic system
일반주제명  
Aerodynamics
일반주제명  
Selenium
일반주제명  
Particle size
일반주제명  
Thyroid gland
일반주제명  
Metabolism
일반주제명  
Dosimetry
일반주제명  
Environmental protection
일반주제명  
Probability distribution
일반주제명  
Ordinary differential equations
일반주제명  
Small intestine
일반주제명  
Lungs
일반주제명  
Aerospace engineering
일반주제명  
Endocrinology
일반주제명  
Mathematics
일반주제명  
Morphology
일반주제명  
Nuclear engineering
일반주제명  
Nuclear physics
기타저자  
Georgia Institute of Technology.
기본자료저록  
Dissertations Abstracts International. 87-05B.
전자적 위치 및 접속  
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MARC

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■1001  ▼aMargot,  Dmitri  Edward.
■24510▼aUncertainty  Analysis  in  ICRP  66  Human  Respiratory  Tract  Model  for  Consequence  Management  Data  Products
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■500    ▼aAdvisor:  Dewji,  Shaheen.
■5021  ▼aThesis  (Ph.D.)--Georgia  Institute  of  Technology,  2024.
■520    ▼aInhaled  radioactive  is  a  unique  hazard.  Once  inhaled  the  radioactive  material  is  translocated  within  the  body  via  incorporation  into  the  metabolism  and  immune  response.  While  metabolizing,  the  radioactive  material  is  irradiating  nearby  tissue.  Since  the  distribution  of  radioactive  material  changes  over  time,  biokinetic  modelling  tracks  the  movement  of  the  radioactive  material  within  organs  and  tissues.  To  determine  the  impact  of  the  input  parameters  into  biokinetic  modelling,  a  software  called  REDCAL  (Radiation  Exposure  Dose  Calculator)  was  developed  in  Python  to  handle  statistically  sampled  parameters  to  compute  the  radiation  dose  from  radionuclides  of  concern  for  emergency  response  planners.  REDCAL  handles  the  inhalation  of  radioactive  particles  and  subsequent  deposition  within  the  airways.  Following  the  deposition  computations,  REDCAL  tracks  the  movement  of  radioactive  material  within  the  body  and  computes  the  effective  dose  to  the  individual  over  a  lifetime.  With  statistically  sampled  input  parameters,  REDCAL  was  used  to  generate  3,410,000  effective  dose  coefficients  to  analyze  the  influence  of  the  input  parameters  on  the  resulting  dose.  As  sets  of  dose  coefficients  were  made  for  each  radionuclide  and  its  associated  lung  clearance  type(s),  a  defined  distribution  of  its  effective  dose  coefficient  as  a  function  of  inhaled  particle  size,  in  AMAD,  were  generated  to  inform  the  sampling  needing  for  computing  derived  response  levels  (DRLs)  by  in  Turbo  FRMAC  by  the  Federal  Radiological  Monitoring  and  Assessment  Center  (FRMAC).  This  dissertation  covers  the  methods,  mathematics,  and  concepts  required  to  compute  particle  deposition  in  the  airways,  solve  biokinetic  models,  and  compute  effective  dose  from  radiation  sources  with  time-dependent  concentrations.
■590    ▼aSchool  code:  0078.
■650  4▼aSoftware
■650  4▼aIodine
■650  4▼aRadiation  protection
■650  4▼aChemical  elements
■650  4▼aLymphatic  system
■650  4▼aAerodynamics
■650  4▼aSelenium
■650  4▼aParticle  size
■650  4▼aThyroid  gland
■650  4▼aMetabolism
■650  4▼aDosimetry
■650  4▼aEnvironmental  protection
■650  4▼aProbability  distribution
■650  4▼aOrdinary  differential  equations
■650  4▼aSmall  intestine
■650  4▼aLungs
■650  4▼aAerospace  engineering
■650  4▼aEndocrinology
■650  4▼aMathematics
■650  4▼aMorphology
■650  4▼aNuclear  engineering
■650  4▼aNuclear  physics
■690    ▼a0538
■690    ▼a0409
■690    ▼a0405
■690    ▼a0287
■690    ▼a0552
■690    ▼a0756
■690    ▼a0354
■71020▼aGeorgia  Institute  of  Technology.
■7730  ▼tDissertations  Abstracts  International▼g87-05B.
■790    ▼a0078
■791    ▼aPh.D.
■792    ▼a2024
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17360678▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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