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Statistical Inference and Learning in Complex Experimental Settings
Statistical Inference and Learning in Complex Experimental Settings
Statistical Inference and Learning in Complex Experimental Settings

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20260202103203
ISBN  
9798280717176
DDC  
310
저자명  
Liang, Biyonka.
서명/저자  
Statistical Inference and Learning in Complex Experimental Settings
발행사항  
[Sl] : Harvard University, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
254 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-12, Section: A.
주기사항  
Advisor: Janson, Lucas.
학위논문주기  
Thesis (Ph.D.)--Harvard University, 2025.
초록/해제  
요약This thesis presents three self-contained chapters: a powerful approach to partial conjunction hypothesis testing, an online reinforcement learning algorithm for scarce resource allocation in public health settings, and an experimental design for anytime valid inference on adaptive experiments.In Chapter 1, we propose a new method for partial conjunction hypothesis (PCH) testing, called the Conditional Partial Conjunction Hypothesis (cPCH) test. PCH tests are necessary to address important statistical questions in a diverse array of fields, from the analysis of causal graphs to the evaluation of scientific replicability. The cPCH test is less conservative, and hence, more powerful than existing approaches, and achieves particular power gains in low-signal regimes commonly encountered in applications such as genetic analysis. In Chapter 2, we propose a new experimental design for adaptive experiments that enables continuous inference on the Average Treatment Effect (ATE), with guarantees on statistical validity and power. In contrast to existing work, our approach does not require the treatment assignment probabilities of the adaptive assignment algorithm to be bounded away from zero and one, making it applicable to nearly any adaptive experimental design, including many common multi-armed bandit algorithms like Thompson sampling and the Upper Confidence Bound method. We empirically show that our design improves the power of ATE inference while maintaining valid finite-sample coverage across a wide array of experimental settings while paying relatively little cost in reward.In Chapter 3, we present a new online reinforcement learning algorithm for allocating scarce interventions in health program. By utilizing hierarchical Bayesian modeling approaches, our algorithm shares information within and across the program participants to learn the underlying transition dynamics quickly, even the algorithm only has a limited time horizon to interact with the system. Through an extensive simulation study, including one setting developed from real data from a mobile health service program in India, we showcase our algorithm's ability to significantly improve retention in health program settings.
일반주제명  
Statistics
일반주제명  
Public health
일반주제명  
Information science
키워드  
Partial conjunction hypothesis testing
키워드  
Average Treatment Effect
키워드  
Conditional Partial Conjunction Hypothesis
기타저자  
Harvard University Statistics
기본자료저록  
Dissertations Abstracts International. 86-12A.
전자적 위치 및 접속  
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MARC

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■1001  ▼aLiang,  Biyonka.▼0(orcid)0000-0002-5461-7829
■24510▼aStatistical  Inference  and  Learning  in  Complex  Experimental  Settings
■260    ▼a[Sl]▼bHarvard  University▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a254  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-12,  Section:  A.
■500    ▼aAdvisor:  Janson,  Lucas.
■5021  ▼aThesis  (Ph.D.)--Harvard  University,  2025.
■520    ▼aThis  thesis  presents  three  self-contained  chapters:  a  powerful  approach  to  partial  conjunction  hypothesis  testing,  an  online  reinforcement  learning  algorithm  for  scarce  resource  allocation  in  public  health  settings,  and  an  experimental  design  for  anytime  valid  inference  on  adaptive  experiments.In  Chapter  1,  we  propose  a  new  method  for  partial  conjunction  hypothesis  (PCH)  testing,  called  the  Conditional  Partial  Conjunction  Hypothesis  (cPCH)  test.  PCH  tests  are  necessary  to  address  important  statistical  questions  in  a  diverse  array  of  fields,  from  the  analysis  of  causal  graphs  to  the  evaluation  of  scientific  replicability.  The  cPCH  test  is  less  conservative,  and  hence,  more  powerful  than  existing  approaches,  and  achieves  particular  power  gains  in  low-signal  regimes  commonly  encountered  in  applications  such  as  genetic  analysis.  In  Chapter  2,  we  propose  a  new  experimental  design  for  adaptive  experiments  that  enables  continuous  inference  on  the  Average  Treatment  Effect  (ATE),  with  guarantees  on  statistical  validity  and  power.  In  contrast  to  existing  work,  our  approach  does  not  require  the  treatment  assignment  probabilities  of  the  adaptive  assignment  algorithm  to  be  bounded  away  from  zero  and  one,  making  it  applicable  to  nearly  any  adaptive  experimental  design,  including  many  common  multi-armed  bandit  algorithms  like  Thompson  sampling  and  the  Upper  Confidence  Bound  method.  We  empirically  show  that  our  design  improves  the  power  of  ATE  inference  while  maintaining  valid  finite-sample  coverage  across  a  wide  array  of  experimental  settings  while  paying  relatively  little  cost  in  reward.In  Chapter  3,  we  present  a  new  online  reinforcement  learning  algorithm  for  allocating  scarce  interventions  in  health  program.  By  utilizing  hierarchical  Bayesian  modeling  approaches,  our  algorithm  shares  information  within  and  across  the  program  participants  to  learn  the  underlying  transition  dynamics  quickly,  even  the  algorithm  only  has  a  limited  time  horizon  to  interact  with  the  system.  Through  an  extensive  simulation  study,  including  one  setting  developed  from  real  data  from  a  mobile  health  service  program  in  India,  we  showcase  our  algorithm's  ability  to  significantly  improve  retention  in  health  program  settings.
■590    ▼aSchool  code:  0084.
■650  4▼aStatistics
■650  4▼aPublic  health
■650  4▼aInformation  science
■653    ▼aPartial  conjunction  hypothesis  testing
■653    ▼aAverage  Treatment  Effect
■653    ▼aConditional  Partial  Conjunction  Hypothesis
■690    ▼a0463
■690    ▼a0800
■690    ▼a0723
■690    ▼a0573
■71020▼aHarvard  University▼bStatistics.
■7730  ▼tDissertations  Abstracts  International▼g86-12A.
■790    ▼a0084
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17357293▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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