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Design and Development of Orally Self-Disintegrating Milk Protein-Rich Extrudates Using Supercritical Fluid Extrusion
Design and Development of Orally Self-Disintegrating Milk Protein-Rich Extrudates Using Su...
Design and Development of Orally Self-Disintegrating Milk Protein-Rich Extrudates Using Supercritical Fluid Extrusion

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자료유형  
 학위논문 서양
최종처리일시  
20260202103204
ISBN  
9798283138237
DDC  
641
저자명  
Uhrin, Jessica.
서명/저자  
Design and Development of Orally Self-Disintegrating Milk Protein-Rich Extrudates Using Supercritical Fluid Extrusion
발행사항  
[Sl] : Cornell University, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
172 p
주기사항  
Source: Dissertations Abstracts International, Volume: 86-12, Section: B.
주기사항  
Advisor: Rizvi, Syed.
학위논문주기  
Thesis (Ph.D.)--Cornell University, 2025.
초록/해제  
요약The overall objective of this work was to design, develop, and evaluate a novel process to create orally self-disintegrating puffs from milk protein with enhanced nutritional, flavor, and textural qualities. The market for such puffs is dominated by carbohydrate-based puffs that are lacking protein and high in sugar, catering primarily to infants and failing to address the nutritional needs of the elderly, many of whom require high-protein foods and may also suffer from swallowing difficulties and lactose intolerance. The first aim of this work was to understand the rheological behaviors of lactose-hydrolyzed and unhydrolyzed skim milk concentrates and reconstituted powder samples prior to supercritical fluid extrusion (SCFX) processing. Formulations containing lactose-hydrolyzed (LHSMP) or unhydrolyzed regular skim milk powder (SMP) in combination with 80% protein-containing milk protein concentrate (MPC80) powder and a calcium chelator, were processed using low-temperature, low- shear SCFX with dense carbon dioxide (CO2) to produce protein-rich puffs that disintegrate in the mouth within 30 seconds. Results indicated that the SCFX puffs were nutritionally enhanced through CO2-induced temporary acidity within the SCFX system, in combination with the galactose within LHSMP, which acted as a precursor to the formation of short-chain galacto- oligosaccharides during extrusion. To ensure the mechanical collapse under realistic oral conditions, the compressive strength properties of these puffs were modeled using variable contact area. To further enhance the consumer appeal, a novel flavor, pigment, and bioactive compound depositing technique was developed that utilizes the solvent properties of SC-CO2 to encapsulate solutes within the internal cell surfaces of the orally self-disintegrating puffs. Both methyl anthranilate and spinach-extracted chlorophyll were successfully deposited within the CO2 filled cellular architecture of the puffs. Additionally, the natural calcium chelators casein phosphopeptide (CPP) and citric acid (CA) were investigated as a possible alternative for phosphate-based calcium chelators. The MPC80-CPP puffs showed calcium chelation efficiency equivalent to the phosphate-based chelators. This research leveraged the multifunctionality of SCFX processing to produce nutritionally superior, clean label, functional snack products for infants and elderly with swallowing difficulty.
일반주제명  
Food science
일반주제명  
Polymer chemistry
일반주제명  
Biochemistry
키워드  
Dysphagia snacks
키워드  
Lactose-hydrolyzed
키워드  
Skim milk powder
키워드  
Orally self-disintegrating puffs
키워드  
Supercritical fluid extrusion
키워드  
Infants
기타저자  
Cornell University Food Science and Technology
기본자료저록  
Dissertations Abstracts International. 86-12B.
전자적 위치 및 접속  
로그인 후 원문을 볼 수 있습니다.

MARC

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■1001  ▼aUhrin,  Jessica.▼0(orcid)0000-0001-6991-1249
■24510▼aDesign  and  Development  of  Orally  Self-Disintegrating  Milk  Protein-Rich  Extrudates  Using  Supercritical  Fluid  Extrusion
■260    ▼a[Sl]▼bCornell  University▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a172  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  86-12,  Section:  B.
■500    ▼aAdvisor:  Rizvi,  Syed.
■5021  ▼aThesis  (Ph.D.)--Cornell  University,  2025.
■520    ▼aThe  overall  objective  of  this  work  was  to  design,  develop,  and  evaluate  a  novel  process  to  create  orally  self-disintegrating  puffs  from  milk  protein  with  enhanced  nutritional,  flavor,  and  textural  qualities.  The  market  for  such  puffs  is  dominated  by  carbohydrate-based  puffs  that  are  lacking  protein  and  high  in  sugar,  catering  primarily  to  infants  and  failing  to  address  the  nutritional  needs  of  the  elderly,  many  of  whom  require  high-protein  foods  and  may  also  suffer  from  swallowing  difficulties  and  lactose  intolerance.  The  first  aim  of  this  work  was  to  understand  the  rheological  behaviors  of  lactose-hydrolyzed  and  unhydrolyzed  skim  milk  concentrates  and  reconstituted  powder  samples  prior  to  supercritical  fluid  extrusion  (SCFX)  processing.  Formulations  containing  lactose-hydrolyzed  (LHSMP)  or  unhydrolyzed  regular  skim  milk  powder  (SMP)  in  combination  with  80%  protein-containing  milk  protein  concentrate  (MPC80)  powder  and  a  calcium  chelator,  were  processed  using  low-temperature,  low-  shear  SCFX  with  dense  carbon  dioxide  (CO2)  to  produce  protein-rich  puffs  that  disintegrate  in  the  mouth  within  30  seconds.  Results  indicated  that  the  SCFX  puffs  were  nutritionally  enhanced  through  CO2-induced  temporary  acidity  within  the  SCFX  system,  in  combination  with  the  galactose  within  LHSMP,  which  acted  as  a  precursor  to  the  formation  of  short-chain  galacto-  oligosaccharides  during  extrusion.  To  ensure  the  mechanical  collapse  under  realistic  oral  conditions,  the  compressive  strength  properties  of  these  puffs  were  modeled  using  variable  contact  area.  To  further  enhance  the  consumer  appeal,  a  novel  flavor,  pigment,  and  bioactive  compound  depositing  technique  was  developed  that  utilizes  the  solvent  properties  of  SC-CO2  to  encapsulate  solutes  within  the  internal  cell  surfaces  of  the  orally  self-disintegrating  puffs.  Both  methyl  anthranilate  and  spinach-extracted  chlorophyll  were  successfully  deposited  within  the  CO2  filled  cellular  architecture  of  the  puffs.  Additionally,  the  natural  calcium  chelators  casein  phosphopeptide  (CPP)  and  citric  acid  (CA)  were  investigated  as  a  possible  alternative  for  phosphate-based  calcium  chelators.  The  MPC80-CPP  puffs  showed  calcium  chelation  efficiency  equivalent  to  the  phosphate-based  chelators.  This  research  leveraged  the  multifunctionality  of  SCFX  processing  to  produce  nutritionally  superior,  clean  label,  functional  snack  products  for  infants  and  elderly  with  swallowing  difficulty.
■590    ▼aSchool  code:  0058.
■650  4▼aFood  science
■650  4▼aPolymer  chemistry
■650  4▼aBiochemistry
■653    ▼aDysphagia  snacks
■653    ▼aLactose-hydrolyzed
■653    ▼aSkim  milk  powder
■653    ▼aOrally  self-disintegrating  puffs
■653    ▼aSupercritical  fluid  extrusion
■653    ▼aInfants
■690    ▼a0359
■690    ▼a0487
■690    ▼a0495
■71020▼aCornell  University▼bFood  Science  and  Technology.
■7730  ▼tDissertations  Abstracts  International▼g86-12B.
■790    ▼a0058
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17357303▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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