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Quarantine in Motion: Pandemic Prevention at the Intersection of Human Mobility, Epidemiology, and AI
Quarantine in Motion: Pandemic Prevention at the Intersection of Human Mobility, Epidemiology, and AI
상세정보
- 자료유형
- 학위논문 서양
- 최종처리일시
- 20260311091541.5
- ISBN
- 9798270229115
- DDC
- 006.31
- 저자명
- Hurtado, Sofia
- 서명/저자
- Quarantine in Motion: Pandemic Prevention at the Intersection of Human Mobility, Epidemiology, and AI / Sofia Hurtado
- 발행사항
- [Sl] : The University of Texas at Austin, 2025
- 형태사항
- 1 electronic resource (132 pages)
- 주기사항
- Source: Dissertations Abstracts International, Volume: 87-06, Section: B.
- 주기사항
- Advisors: Marculescu, Radu Committee members: Barber, Suzanne; de Veciana, Gustavo; Drake, Justin; Julien, Christine.
- 학위논문주기
- - Ph.D. : The University of Texas at Austin, 2025.
- 초록/해제
- 요약The rapid spread of airborne infectious diseases, such as COVID-19, has highlighted the need for more effective and scalable disease mitigation strategies beyond traditional manual contact tracing and exposure notification applications. This dissertation explores the novel paradigm of "Quarantine in Motion", which enables individuals to maintain mobility while reducing disease transmission risk. By leveraging graph neural networks (GNNs), multi-agent reinforcement learning (MARL), and real-world human mobility data, this work develops an integrated framework for predicting high-risk locations, identifying transmission pathways, and optimizing mobility strategies to mitigate outbreaks. To extend disease contact tracing from reactive to proactive risk management, we introduce risk-informed exposure prediction, where GNNs process Foursquare lo- cation data to forecast hourly disease hotspots. Simulating over 36,000 risk-aware agents in Austin, TX, we show that even after 50% of the population has been infected, individuals can still maintain mobility while reducing new infections by 13%. Further, we propose a network science-based approach to dynamically construct and prune contact networks for recurring interactions, which significantly improves the accuracy of individual-level epidemic predictions. Using mobility data from 1.3 million devices, we validate this framework across two major U.S. cities, Austin and New York City, demonstrating improved outbreak curve estimation with reduced model uncertainty. To enhance the effectiveness of automated contact tracing, we introduce Infectious Path Centrality, a novel network metric that enables graph learning-based edge classification, achieving a 94% F1-score in identifying key transmission events. We further demonstrate that bidirectional contact tracing, which retroactively and proactively isolates potential infections, reduces the effective reproduction rate by 71%, outperforming traditional forward tracing. Finally, we present an online automated disease-aware navigation system that dynamically infers health states and deploys mobility-aware agents, achieving a 92% backwards-tracing F1-score and reducing disease spread by 29%, even under conditions of probabilistic testing and social hesitancy. By integrating graph learning, reinforcement learning, and network-based dis- ease modeling, this dissertation provides a robust framework for real-time epidemic mitigation. The proposed methods bridge the gap between individual-level risk management and population-scale disease control, offering scalable, data-driven solutions for future pandemics.
- 언어주기
- English
- 일반주제명
- Public health
- 일반주제명
- Computer science
- 일반주제명
- Biostatistics
- 일반주제명
- Epidemiology
- 키워드
- Mobility
- 기타저자
- The University of Texas at Austin Electrical and Computer Engineering
- 기본자료저록
- Dissertations Abstracts International. 87-06B.
- 전자적 위치 및 접속
- 로그인 후 원문을 볼 수 있습니다.
MARC
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■006m o d
■007cr|nu||||||||
■020 ▼a9798270229115
■040 ▼aMiAaPQD▼beng▼cMiAaPQD▼erda
■082 ▼a006.31
■1001 ▼aHurtado, Sofia▼eauthor.
■24510▼aQuarantine in Motion: Pandemic Prevention at the Intersection of Human Mobility, Epidemiology, and AI ▼cSofia Hurtado
■260 ▼a[Sl]▼bThe University of Texas at Austin▼c2025
■264 1▼aAnn Arbor▼bProQuest Dissertations & Theses▼c2025
■300 ▼a1 electronic resource (132 pages)
■336 ▼atext▼btxt▼2rdacontent
■337 ▼acomputer▼bc▼2rdamedia
■338 ▼aonline resource▼bcr▼2rdacarrier
■500 ▼aSource: Dissertations Abstracts International, Volume: 87-06, Section: B.
■500 ▼aAdvisors: Marculescu, Radu Committee members: Barber, Suzanne; de Veciana, Gustavo; Drake, Justin; Julien, Christine.
■5021 ▼bPh.D.▼cThe University of Texas at Austin▼d2025.
■520 ▼aThe rapid spread of airborne infectious diseases, such as COVID-19, has highlighted the need for more effective and scalable disease mitigation strategies beyond traditional manual contact tracing and exposure notification applications. This dissertation explores the novel paradigm of "Quarantine in Motion", which enables individuals to maintain mobility while reducing disease transmission risk. By leveraging graph neural networks (GNNs), multi-agent reinforcement learning (MARL), and real-world human mobility data, this work develops an integrated framework for predicting high-risk locations, identifying transmission pathways, and optimizing mobility strategies to mitigate outbreaks. To extend disease contact tracing from reactive to proactive risk management, we introduce risk-informed exposure prediction, where GNNs process Foursquare lo- cation data to forecast hourly disease hotspots. Simulating over 36,000 risk-aware agents in Austin, TX, we show that even after 50% of the population has been infected, individuals can still maintain mobility while reducing new infections by 13%. Further, we propose a network science-based approach to dynamically construct and prune contact networks for recurring interactions, which significantly improves the accuracy of individual-level epidemic predictions. Using mobility data from 1.3 million devices, we validate this framework across two major U.S. cities, Austin and New York City, demonstrating improved outbreak curve estimation with reduced model uncertainty. To enhance the effectiveness of automated contact tracing, we introduce Infectious Path Centrality, a novel network metric that enables graph learning-based edge classification, achieving a 94% F1-score in identifying key transmission events. We further demonstrate that bidirectional contact tracing, which retroactively and proactively isolates potential infections, reduces the effective reproduction rate by 71%, outperforming traditional forward tracing. Finally, we present an online automated disease-aware navigation system that dynamically infers health states and deploys mobility-aware agents, achieving a 92% backwards-tracing F1-score and reducing disease spread by 29%, even under conditions of probabilistic testing and social hesitancy. By integrating graph learning, reinforcement learning, and network-based dis- ease modeling, this dissertation provides a robust framework for real-time epidemic mitigation. The proposed methods bridge the gap between individual-level risk management and population-scale disease control, offering scalable, data-driven solutions for future pandemics.
■546 ▼aEnglish
■590 ▼aSchool code: 0227
■650 4▼aPublic health
■650 4▼aComputer science
■650 4▼aBiostatistics
■650 4▼aEpidemiology
■653 ▼aQuarantine in Motion
■653 ▼aDisease transmission
■653 ▼aTransmission pathways
■653 ▼aMobility
■653 ▼aGraph neural networks
■7102 ▼aThe University of Texas at Austin▼bElectrical and Computer Engineering.▼edegree granting institution.
■7201 ▼aMarculescu, Radu▼edegree supervisor.
■7730 ▼tDissertations Abstracts International▼g87-06B.
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17361126▼nKERIS▼z이 자료의 원문은 한국교육학술정보원에서 제공합니다.


