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Capturing Epidemic Dynamics Through Epidemic Surveillance Panels: Approximating Agent-Based Models Using Dynamical Survival Analysis
Capturing Epidemic Dynamics Through Epidemic Surveillance Panels: Approximating Agent-Base...
Capturing Epidemic Dynamics Through Epidemic Surveillance Panels: Approximating Agent-Based Models Using Dynamical Survival Analysis

상세정보

자료유형  
 학위논문 서양
최종처리일시  
20260202105633
ISBN  
9798297962033
DDC  
312
저자명  
Richter, Micaela.
서명/저자  
Capturing Epidemic Dynamics Through Epidemic Surveillance Panels: Approximating Agent-Based Models Using Dynamical Survival Analysis
발행사항  
[Sl] : The Ohio State University, 2025
발행사항  
Ann Arbor : ProQuest Dissertations & Theses, 2025
형태사항  
134 p
주기사항  
Source: Dissertations Abstracts International, Volume: 87-05, Section: A.
주기사항  
Advisor: Rempala, Grzegorz;Kenah, Eben.
학위논문주기  
Thesis (Ph.D.)--The Ohio State University, 2025.
초록/해제  
요약Epidemic models have been used to characterize disease dynamics, inform public health interventions, and forecast epidemic spread and its impact on healthcare systems. However, compartmental models are limited in their ability to account for complex dynamics rooted in population heterogeneities. Additionally, these models are often fit using time series of cases detected through clinical testing or other data streams that can produce biased estimates of key epidemiological parameters. This dissertation addresses these limitations by developing a modeling framework that uses compartmental models to locally approximate complex epidemic dynamics. This approach can capture changes in epidemic dynamics due to factors such as changes in human behavior, environment, and pathogen. The first study introduces an agentbased model of the United States and explores three key drivers of racial and ethnic disparities: household composition, occupation, and school setting. The second study extends a modeling framework called dynamical survival analysis (DSA) for estimating epidemic parameters from individual observed infection histories measured in an epidemic surveillance panel, which is a random sample from the population that is followed longitudinally. In the third study, we show how DSA and epidemic surveillance panels could be used to produce more accurate estimates of the effective reproduction number Rt. Collectively, these studies underscore the need for high-resolution, individual-level data streams like those provided by an epidemic surveillance panel.
일반주제명  
Demography
일반주제명  
Epidemiology
일반주제명  
Biostatistics
일반주제명  
Public health
키워드  
Population heterogeneity
키워드  
Modeling
키워드  
Agent-based models
키워드  
Survival analysis
키워드  
Forecasting
키워드  
Surveillance
기타저자  
The Ohio State University Biostatistics
기본자료저록  
Dissertations Abstracts International. 87-05A.
전자적 위치 및 접속  
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MARC

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■1001  ▼aRichter,  Micaela.
■24510▼aCapturing  Epidemic  Dynamics  Through  Epidemic  Surveillance  Panels:  Approximating  Agent-Based  Models  Using  Dynamical  Survival  Analysis
■260    ▼a[Sl]▼bThe  Ohio  State  University▼c2025
■260  1▼aAnn  Arbor▼bProQuest  Dissertations  &  Theses▼c2025
■300    ▼a134  p
■500    ▼aSource:  Dissertations  Abstracts  International,  Volume:  87-05,  Section:  A.
■500    ▼aAdvisor:  Rempala,  Grzegorz;Kenah,  Eben.
■5021  ▼aThesis  (Ph.D.)--The  Ohio  State  University,  2025.
■520    ▼aEpidemic  models  have  been  used  to  characterize  disease  dynamics,  inform  public  health  interventions,  and  forecast  epidemic  spread  and  its  impact  on  healthcare  systems.  However,  compartmental  models  are  limited  in  their  ability  to  account  for  complex  dynamics  rooted  in  population  heterogeneities.  Additionally,  these  models  are  often  fit  using  time  series  of  cases  detected  through  clinical  testing  or  other  data  streams  that  can  produce  biased  estimates  of  key  epidemiological  parameters.  This  dissertation  addresses  these  limitations  by  developing  a  modeling  framework  that  uses  compartmental  models  to  locally  approximate  complex  epidemic  dynamics.  This  approach  can  capture  changes  in  epidemic  dynamics  due  to  factors  such  as  changes  in  human  behavior,  environment,  and  pathogen.  The  first  study  introduces  an  agentbased  model  of  the  United  States  and  explores  three  key  drivers  of  racial  and  ethnic  disparities:  household  composition,  occupation,  and  school  setting.  The  second  study  extends  a  modeling  framework  called  dynamical  survival  analysis  (DSA)  for  estimating  epidemic  parameters  from  individual  observed  infection  histories  measured  in  an  epidemic  surveillance  panel,  which  is  a  random  sample  from  the  population  that  is  followed  longitudinally.  In  the  third  study,  we  show  how  DSA  and  epidemic  surveillance  panels  could  be  used  to  produce  more  accurate  estimates  of  the  effective  reproduction  number  Rt.  Collectively,  these  studies  underscore  the  need  for  high-resolution,  individual-level  data  streams  like  those  provided  by  an  epidemic  surveillance  panel.
■590    ▼aSchool  code:  0168.
■650  4▼aDemography
■650  4▼aEpidemiology
■650  4▼aBiostatistics
■650  4▼aPublic  health
■653    ▼aPopulation  heterogeneity
■653    ▼aModeling
■653    ▼aAgent-based  models
■653    ▼aSurvival  analysis
■653    ▼aForecasting
■653    ▼aSurveillance
■690    ▼a0938
■690    ▼a0766
■690    ▼a0308
■690    ▼a0573
■71020▼aThe  Ohio  State  University▼bBiostatistics.
■7730  ▼tDissertations  Abstracts  International▼g87-05A.
■790    ▼a0168
■791    ▼aPh.D.
■792    ▼a2025
■793    ▼aEnglish
■85640▼uhttp://www.riss.kr/pdu/ddodLink.do?id=T17360888▼nKERIS▼z이  자료의  원문은  한국교육학술정보원에서  제공합니다.

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